Algorithms
Y. Guan, Myers, C. L., Hess, D. C., Barutcuoglu, Z., Caudy, A. A., and Troyanskaya, O. G.,
“Predicting gene function in a hierarchical context with an ensemble of classifiers.”,
Genome Biol, vol. 9 Suppl 1, p. S3, 2008.
E. M. Airoldi, Huttenhower, C., Gresham, D., Lu, C., Caudy, A. A., Dunham, M. J., Broach, J. R., Botstein, D., and Troyanskaya, O. G.,
“Predicting cellular growth from gene expression signatures.”,
PLoS Comput Biol, vol. 5, no. 1, p. e1000257, 2009.
J. S. Bloom, Khan, Z., Kruglyak, L., Singh, M., and Caudy, A. A.,
“Measuring differential gene expression by short read sequencing: quantitative comparison to 2-channel gene expression microarrays.”,
BMC Genomics, vol. 10, p. 221, 2009.
Z. Khan, Amini, S., Bloom, J. S., Ruse, C., Caudy, A. A., Kruglyak, L., Singh, M., Perlman, D. H., and Tavazoie, S.,
“Accurate proteome-wide protein quantification from high-resolution 15N mass spectra.”,
Genome Biol, vol. 12, no. 12, p. R122, 2011.
C. Huttenhower, Hibbs, M. A., Myers, C. L., Caudy, A. A., Hess, D. C., and Troyanskaya, O. G.,
“The impact of incomplete knowledge on evaluation: an experimental benchmark for protein function prediction.”,
Bioinformatics, vol. 25, no. 18, pp. 2404-10, 2009.
Alleles
Z. Khan, Bloom, J. S., Amini, S., Singh, M., Perlman, D. H., Caudy, A. A., and Kruglyak, L.,
“Quantitative measurement of allele-specific protein expression in a diploid yeast hybrid by LC-MS.”,
Mol Syst Biol, vol. 8, p. 602, 2012.
Amino Acid Sequence
Z. Khan, Amini, S., Bloom, J. S., Ruse, C., Caudy, A. A., Kruglyak, L., Singh, M., Perlman, D. H., and Tavazoie, S.,
“Accurate proteome-wide protein quantification from high-resolution 15N mass spectra.”,
Genome Biol, vol. 12, no. 12, p. R122, 2011.
AMP-Activated Protein Kinases
Y. - F. Xu, Létisse, F., Absalan, F., Lu, W., Kuznetsova, E., Brown, G., Caudy, A. A., Yakunin, A. F., Broach, J. R., and Rabinowitz, J. D.,
“Nucleotide degradation and ribose salvage in yeast.”,
Mol Syst Biol, vol. 9, p. 665, 2013.
Animals
Y. Guan, Myers, C. L., Hess, D. C., Barutcuoglu, Z., Caudy, A. A., and Troyanskaya, O. G.,
“Predicting gene function in a hierarchical context with an ensemble of classifiers.”,
Genome Biol, vol. 9 Suppl 1, p. S3, 2008.
Bacterial Proteins
Z. Khan, Amini, S., Bloom, J. S., Ruse, C., Caudy, A. A., Kruglyak, L., Singh, M., Perlman, D. H., and Tavazoie, S.,
“Accurate proteome-wide protein quantification from high-resolution 15N mass spectra.”,
Genome Biol, vol. 12, no. 12, p. R122, 2011.
Bayes Theorem
Y. Guan, Myers, C. L., Hess, D. C., Barutcuoglu, Z., Caudy, A. A., and Troyanskaya, O. G.,
“Predicting gene function in a hierarchical context with an ensemble of classifiers.”,
Genome Biol, vol. 9 Suppl 1, p. S3, 2008.
Biology
M. A. Hibbs, Myers, C. L., Huttenhower, C., Hess, D. C., Li, K., Caudy, A. A., and Troyanskaya, O. G.,
“Directing experimental biology: a case study in mitochondrial biogenesis.”,
PLoS Comput Biol, vol. 5, no. 3, p. e1000322, 2009.
Biosynthetic Pathways
M. F. Clasquin, Melamud, E., Singer, A., Gooding, J. R., Xu, X., Dong, A., Cui, H., Campagna, S. R., Savchenko, A., Yakunin, A. F., Rabinowitz, J. D., and Caudy, A. A.,
“Riboneogenesis in yeast.”,
Cell, vol. 145, no. 6, pp. 969-80, 2011.
Cell Proliferation
E. M. Airoldi, Huttenhower, C., Gresham, D., Lu, C., Caudy, A. A., Dunham, M. J., Broach, J. R., Botstein, D., and Troyanskaya, O. G.,
“Predicting cellular growth from gene expression signatures.”,
PLoS Comput Biol, vol. 5, no. 1, p. e1000257, 2009.
Cell Respiration
D. C. Hess, Myers, C. L., Huttenhower, C., Hibbs, M. A., Hayes, A. P., Paw, J., Clore, J. J., Mendoza, R. M., San Luis, B., Nislow, C., Giaever, G., Costanzo, M., Troyanskaya, O. G., and Caudy, A. A.,
“Computationally driven, quantitative experiments discover genes required for mitochondrial biogenesis.”,
PLoS Genet, vol. 5, no. 3, p. e1000407, 2009.
Chromatography, High Pressure Liquid
W. Lu, Clasquin, M. F., Melamud, E., Amador-Noguez, D., Caudy, A. A., and Rabinowitz, J. D.,
“Metabolomic analysis via reversed-phase ion-pairing liquid chromatography coupled to a stand alone orbitrap mass spectrometer.”,
Anal Chem, vol. 82, no. 8, pp. 3212-21, 2010.
Chromatography, Liquid
Z. Khan, Bloom, J. S., Amini, S., Singh, M., Perlman, D. H., Caudy, A. A., and Kruglyak, L.,
“Quantitative measurement of allele-specific protein expression in a diploid yeast hybrid by LC-MS.”,
Mol Syst Biol, vol. 8, p. 602, 2012.
Chromatography, Reverse-Phase
W. Lu, Clasquin, M. F., Melamud, E., Amador-Noguez, D., Caudy, A. A., and Rabinowitz, J. D.,
“Metabolomic analysis via reversed-phase ion-pairing liquid chromatography coupled to a stand alone orbitrap mass spectrometer.”,
Anal Chem, vol. 82, no. 8, pp. 3212-21, 2010.
Computational Biology
C. Huttenhower, Hibbs, M. A., Myers, C. L., Caudy, A. A., Hess, D. C., and Troyanskaya, O. G.,
“The impact of incomplete knowledge on evaluation: an experimental benchmark for protein function prediction.”,
Bioinformatics, vol. 25, no. 18, pp. 2404-10, 2009.
Computer Simulation
M. A. Hibbs, Myers, C. L., Huttenhower, C., Hess, D. C., Li, K., Caudy, A. A., and Troyanskaya, O. G.,
“Directing experimental biology: a case study in mitochondrial biogenesis.”,
PLoS Comput Biol, vol. 5, no. 3, p. e1000322, 2009.
E. M. Airoldi, Huttenhower, C., Gresham, D., Lu, C., Caudy, A. A., Dunham, M. J., Broach, J. R., Botstein, D., and Troyanskaya, O. G.,
“Predicting cellular growth from gene expression signatures.”,
PLoS Comput Biol, vol. 5, no. 1, p. e1000257, 2009.
Crystallography, X-Ray
M. F. Clasquin, Melamud, E., Singer, A., Gooding, J. R., Xu, X., Dong, A., Cui, H., Campagna, S. R., Savchenko, A., Yakunin, A. F., Rabinowitz, J. D., and Caudy, A. A.,
“Riboneogenesis in yeast.”,
Cell, vol. 145, no. 6, pp. 969-80, 2011.
Cyclic AMP-Dependent Protein Kinases
Y. - F. Xu, Létisse, F., Absalan, F., Lu, W., Kuznetsova, E., Brown, G., Caudy, A. A., Yakunin, A. F., Broach, J. R., and Rabinowitz, J. D.,
“Nucleotide degradation and ribose salvage in yeast.”,
Mol Syst Biol, vol. 9, p. 665, 2013.
Cytoplasm
D. C. Hess, Myers, C. L., Huttenhower, C., Hibbs, M. A., Hayes, A. P., Paw, J., Clore, J. J., Mendoza, R. M., San Luis, B., Nislow, C., Giaever, G., Costanzo, M., Troyanskaya, O. G., and Caudy, A. A.,
“Computationally driven, quantitative experiments discover genes required for mitochondrial biogenesis.”,
PLoS Genet, vol. 5, no. 3, p. e1000407, 2009.
Databases, Protein
C. Huttenhower, Hibbs, M. A., Myers, C. L., Caudy, A. A., Hess, D. C., and Troyanskaya, O. G.,
“The impact of incomplete knowledge on evaluation: an experimental benchmark for protein function prediction.”,
Bioinformatics, vol. 25, no. 18, pp. 2404-10, 2009.
DNA Barcoding, Taxonomic
P. A. Gibney, Lu, C., Caudy, A. A., Hess, D. C., and Botstein, D.,
“Yeast metabolic and signaling genes are required for heat-shock survival and have little overlap with the heat-induced genes.”,
Proc Natl Acad Sci U S A, vol. 110, no. 46, pp. E4393-402, 2013.
DNA Primers
P. A. Gibney, Lu, C., Caudy, A. A., Hess, D. C., and Botstein, D.,
“Yeast metabolic and signaling genes are required for heat-shock survival and have little overlap with the heat-induced genes.”,
Proc Natl Acad Sci U S A, vol. 110, no. 46, pp. E4393-402, 2013.
DNA, Complementary
J. S. Bloom, Khan, Z., Kruglyak, L., Singh, M., and Caudy, A. A.,
“Measuring differential gene expression by short read sequencing: quantitative comparison to 2-channel gene expression microarrays.”,
BMC Genomics, vol. 10, p. 221, 2009.
DNA, Fungal
J. S. Bloom, Khan, Z., Kruglyak, L., Singh, M., and Caudy, A. A.,
“Measuring differential gene expression by short read sequencing: quantitative comparison to 2-channel gene expression microarrays.”,
BMC Genomics, vol. 10, p. 221, 2009.
Epistasis, Genetic
M. Costanzo, VanderSluis, B., Koch, E. N., Baryshnikova, A., Pons, C., Tan, G., Wang, W., Usaj, M., Hanchard, J., Lee, S. D., Pelechano, V., Styles, E. B., Billmann, M., van Leeuwen, J., van Dyk, N., Lin, Z. - Y., Kuzmin, E., Nelson, J., Piotrowski, J. S., Srikumar, T., Bahr, S., Chen, Y., Deshpande, R., Kurat, C. F., Li, S. C., Li, Z., Usaj, M. Mattiazzi, Okada, H., Pascoe, N., San Luis, B. - J., Sharifpoor, S., Shuteriqi, E., Simpkins, S. W., Snider, J., Suresh, H. Garadi, Tan, Y., Zhu, H., Malod-Dognin, N., Janjic, V., Przulj, N., Troyanskaya, O. G., Stagljar, I., Xia, T., Ohya, Y., Gingras, A. - C., Raught, B., Boutros, M., Steinmetz, L. M., Moore, C. L., Rosebrock, A. P., Caudy, A. A., Myers, C. L., Andrews, B., and Boone, C.,
“A global genetic interaction network maps a wiring diagram of cellular function.”,
Science, vol. 353, no. 6306, 2016.
Escherichia coli
Z. Khan, Amini, S., Bloom, J. S., Ruse, C., Caudy, A. A., Kruglyak, L., Singh, M., Perlman, D. H., and Tavazoie, S.,
“Accurate proteome-wide protein quantification from high-resolution 15N mass spectra.”,
Genome Biol, vol. 12, no. 12, p. R122, 2011.
Evolution, Molecular
Y. Guan, Dunham, M. J., Troyanskaya, O. G., and Caudy, A. A.,
“Comparative gene expression between two yeast species.”,
BMC Genomics, vol. 14, p. 33, 2013.
Fungal Proteins
A. A. Caudy, Guan, Y., Jia, Y., Hansen, C., DeSevo, C., Hayes, A. P., Agee, J., Alvarez-Dominguez, J. R., Arellano, H., Barrett, D., Bauerle, C., Bisaria, N., Bradley, P. H., J Breunig, S., Bush, E., Cappel, D., Capra, E., Chen, W., Clore, J., Combs, P. A., Doucette, C., Demuren, O., Fellowes, P., Freeman, S., Frenkel, E., Gadala-Maria, D., Gawande, R., Glass, D., Grossberg, S., Gupta, A., Hammonds-Odie, L., Hoisos, A., Hsi, J., Hsu, Y. - H. Huang, Inukai, S., Karczewski, K. J., Ke, X., Kojima, M., Leachman, S., Lieber, D., Liebowitz, A., Liu, J., Liu, Y., Martin, T., Mena, J., Mendoza, R., Myhrvold, C., Millian, C., Pfau, S., Raj, S., Rich, M., Rokicki, J., Rounds, W., Salazar, M., Salesi, M., Sharma, R., Silverman, S., Singer, C., Sinha, S., Staller, M., Stern, P., Tang, H., Weeks, S., Weidmann, M., Wolf, A., Young, C., Yuan, J., Crutchfield, C., McClean, M., Murphy, C. T., Llinás, M., Botstein, D., Troyanskaya, O. G., and Dunham, M. J.,
“A new system for comparative functional genomics of Saccharomyces yeasts.”,
Genetics, vol. 195, no. 1, pp. 275-87, 2013.
Z. Khan, Bloom, J. S., Amini, S., Singh, M., Perlman, D. H., Caudy, A. A., and Kruglyak, L.,
“Quantitative measurement of allele-specific protein expression in a diploid yeast hybrid by LC-MS.”,
Mol Syst Biol, vol. 8, p. 602, 2012.
Gene Deletion
P. A. Gibney, Lu, C., Caudy, A. A., Hess, D. C., and Botstein, D.,
“Yeast metabolic and signaling genes are required for heat-shock survival and have little overlap with the heat-induced genes.”,
Proc Natl Acad Sci U S A, vol. 110, no. 46, pp. E4393-402, 2013.
M. F. Clasquin, Melamud, E., Singer, A., Gooding, J. R., Xu, X., Dong, A., Cui, H., Campagna, S. R., Savchenko, A., Yakunin, A. F., Rabinowitz, J. D., and Caudy, A. A.,
“Riboneogenesis in yeast.”,
Cell, vol. 145, no. 6, pp. 969-80, 2011.
Gene Expression Profiling
A. A. Caudy, Guan, Y., Jia, Y., Hansen, C., DeSevo, C., Hayes, A. P., Agee, J., Alvarez-Dominguez, J. R., Arellano, H., Barrett, D., Bauerle, C., Bisaria, N., Bradley, P. H., J Breunig, S., Bush, E., Cappel, D., Capra, E., Chen, W., Clore, J., Combs, P. A., Doucette, C., Demuren, O., Fellowes, P., Freeman, S., Frenkel, E., Gadala-Maria, D., Gawande, R., Glass, D., Grossberg, S., Gupta, A., Hammonds-Odie, L., Hoisos, A., Hsi, J., Hsu, Y. - H. Huang, Inukai, S., Karczewski, K. J., Ke, X., Kojima, M., Leachman, S., Lieber, D., Liebowitz, A., Liu, J., Liu, Y., Martin, T., Mena, J., Mendoza, R., Myhrvold, C., Millian, C., Pfau, S., Raj, S., Rich, M., Rokicki, J., Rounds, W., Salazar, M., Salesi, M., Sharma, R., Silverman, S., Singer, C., Sinha, S., Staller, M., Stern, P., Tang, H., Weeks, S., Weidmann, M., Wolf, A., Young, C., Yuan, J., Crutchfield, C., McClean, M., Murphy, C. T., Llinás, M., Botstein, D., Troyanskaya, O. G., and Dunham, M. J.,
“A new system for comparative functional genomics of Saccharomyces yeasts.”,
Genetics, vol. 195, no. 1, pp. 275-87, 2013.
P. A. Gibney, Lu, C., Caudy, A. A., Hess, D. C., and Botstein, D.,
“Yeast metabolic and signaling genes are required for heat-shock survival and have little overlap with the heat-induced genes.”,
Proc Natl Acad Sci U S A, vol. 110, no. 46, pp. E4393-402, 2013.
E. M. Airoldi, Huttenhower, C., Gresham, D., Lu, C., Caudy, A. A., Dunham, M. J., Broach, J. R., Botstein, D., and Troyanskaya, O. G.,
“Predicting cellular growth from gene expression signatures.”,
PLoS Comput Biol, vol. 5, no. 1, p. e1000257, 2009.
J. S. Bloom, Khan, Z., Kruglyak, L., Singh, M., and Caudy, A. A.,
“Measuring differential gene expression by short read sequencing: quantitative comparison to 2-channel gene expression microarrays.”,
BMC Genomics, vol. 10, p. 221, 2009.
Y. Guan, Dunham, M. J., Troyanskaya, O. G., and Caudy, A. A.,
“Comparative gene expression between two yeast species.”,
BMC Genomics, vol. 14, p. 33, 2013.
Z. Khan, Bloom, J. S., Amini, S., Singh, M., Perlman, D. H., Caudy, A. A., and Kruglyak, L.,
“Quantitative measurement of allele-specific protein expression in a diploid yeast hybrid by LC-MS.”,
Mol Syst Biol, vol. 8, p. 602, 2012.
Gene Expression Regulation, Fungal
P. A. Gibney, Lu, C., Caudy, A. A., Hess, D. C., and Botstein, D.,
“Yeast metabolic and signaling genes are required for heat-shock survival and have little overlap with the heat-induced genes.”,
Proc Natl Acad Sci U S A, vol. 110, no. 46, pp. E4393-402, 2013.
Y. - F. Xu, Létisse, F., Absalan, F., Lu, W., Kuznetsova, E., Brown, G., Caudy, A. A., Yakunin, A. F., Broach, J. R., and Rabinowitz, J. D.,
“Nucleotide degradation and ribose salvage in yeast.”,
Mol Syst Biol, vol. 9, p. 665, 2013.
Y. Guan, Dunham, M. J., Troyanskaya, O. G., and Caudy, A. A.,
“Comparative gene expression between two yeast species.”,
BMC Genomics, vol. 14, p. 33, 2013.
Z. Khan, Bloom, J. S., Amini, S., Singh, M., Perlman, D. H., Caudy, A. A., and Kruglyak, L.,
“Quantitative measurement of allele-specific protein expression in a diploid yeast hybrid by LC-MS.”,
Mol Syst Biol, vol. 8, p. 602, 2012.
Gene Regulatory Networks
M. Costanzo, VanderSluis, B., Koch, E. N., Baryshnikova, A., Pons, C., Tan, G., Wang, W., Usaj, M., Hanchard, J., Lee, S. D., Pelechano, V., Styles, E. B., Billmann, M., van Leeuwen, J., van Dyk, N., Lin, Z. - Y., Kuzmin, E., Nelson, J., Piotrowski, J. S., Srikumar, T., Bahr, S., Chen, Y., Deshpande, R., Kurat, C. F., Li, S. C., Li, Z., Usaj, M. Mattiazzi, Okada, H., Pascoe, N., San Luis, B. - J., Sharifpoor, S., Shuteriqi, E., Simpkins, S. W., Snider, J., Suresh, H. Garadi, Tan, Y., Zhu, H., Malod-Dognin, N., Janjic, V., Przulj, N., Troyanskaya, O. G., Stagljar, I., Xia, T., Ohya, Y., Gingras, A. - C., Raught, B., Boutros, M., Steinmetz, L. M., Moore, C. L., Rosebrock, A. P., Caudy, A. A., Myers, C. L., Andrews, B., and Boone, C.,
“A global genetic interaction network maps a wiring diagram of cellular function.”,
Science, vol. 353, no. 6306, 2016.
Genes, Essential
M. Costanzo, VanderSluis, B., Koch, E. N., Baryshnikova, A., Pons, C., Tan, G., Wang, W., Usaj, M., Hanchard, J., Lee, S. D., Pelechano, V., Styles, E. B., Billmann, M., van Leeuwen, J., van Dyk, N., Lin, Z. - Y., Kuzmin, E., Nelson, J., Piotrowski, J. S., Srikumar, T., Bahr, S., Chen, Y., Deshpande, R., Kurat, C. F., Li, S. C., Li, Z., Usaj, M. Mattiazzi, Okada, H., Pascoe, N., San Luis, B. - J., Sharifpoor, S., Shuteriqi, E., Simpkins, S. W., Snider, J., Suresh, H. Garadi, Tan, Y., Zhu, H., Malod-Dognin, N., Janjic, V., Przulj, N., Troyanskaya, O. G., Stagljar, I., Xia, T., Ohya, Y., Gingras, A. - C., Raught, B., Boutros, M., Steinmetz, L. M., Moore, C. L., Rosebrock, A. P., Caudy, A. A., Myers, C. L., Andrews, B., and Boone, C.,
“A global genetic interaction network maps a wiring diagram of cellular function.”,
Science, vol. 353, no. 6306, 2016.
Genes, Fungal
M. Costanzo, VanderSluis, B., Koch, E. N., Baryshnikova, A., Pons, C., Tan, G., Wang, W., Usaj, M., Hanchard, J., Lee, S. D., Pelechano, V., Styles, E. B., Billmann, M., van Leeuwen, J., van Dyk, N., Lin, Z. - Y., Kuzmin, E., Nelson, J., Piotrowski, J. S., Srikumar, T., Bahr, S., Chen, Y., Deshpande, R., Kurat, C. F., Li, S. C., Li, Z., Usaj, M. Mattiazzi, Okada, H., Pascoe, N., San Luis, B. - J., Sharifpoor, S., Shuteriqi, E., Simpkins, S. W., Snider, J., Suresh, H. Garadi, Tan, Y., Zhu, H., Malod-Dognin, N., Janjic, V., Przulj, N., Troyanskaya, O. G., Stagljar, I., Xia, T., Ohya, Y., Gingras, A. - C., Raught, B., Boutros, M., Steinmetz, L. M., Moore, C. L., Rosebrock, A. P., Caudy, A. A., Myers, C. L., Andrews, B., and Boone, C.,
“A global genetic interaction network maps a wiring diagram of cellular function.”,
Science, vol. 353, no. 6306, 2016.
Genes, Mitochondrial
D. C. Hess, Myers, C. L., Huttenhower, C., Hibbs, M. A., Hayes, A. P., Paw, J., Clore, J. J., Mendoza, R. M., San Luis, B., Nislow, C., Giaever, G., Costanzo, M., Troyanskaya, O. G., and Caudy, A. A.,
“Computationally driven, quantitative experiments discover genes required for mitochondrial biogenesis.”,
PLoS Genet, vol. 5, no. 3, p. e1000407, 2009.
Genetic Markers
P. A. Gibney, Lu, C., Caudy, A. A., Hess, D. C., and Botstein, D.,
“Yeast metabolic and signaling genes are required for heat-shock survival and have little overlap with the heat-induced genes.”,
Proc Natl Acad Sci U S A, vol. 110, no. 46, pp. E4393-402, 2013.
Genetic Pleiotropy
M. Costanzo, VanderSluis, B., Koch, E. N., Baryshnikova, A., Pons, C., Tan, G., Wang, W., Usaj, M., Hanchard, J., Lee, S. D., Pelechano, V., Styles, E. B., Billmann, M., van Leeuwen, J., van Dyk, N., Lin, Z. - Y., Kuzmin, E., Nelson, J., Piotrowski, J. S., Srikumar, T., Bahr, S., Chen, Y., Deshpande, R., Kurat, C. F., Li, S. C., Li, Z., Usaj, M. Mattiazzi, Okada, H., Pascoe, N., San Luis, B. - J., Sharifpoor, S., Shuteriqi, E., Simpkins, S. W., Snider, J., Suresh, H. Garadi, Tan, Y., Zhu, H., Malod-Dognin, N., Janjic, V., Przulj, N., Troyanskaya, O. G., Stagljar, I., Xia, T., Ohya, Y., Gingras, A. - C., Raught, B., Boutros, M., Steinmetz, L. M., Moore, C. L., Rosebrock, A. P., Caudy, A. A., Myers, C. L., Andrews, B., and Boone, C.,
“A global genetic interaction network maps a wiring diagram of cellular function.”,
Science, vol. 353, no. 6306, 2016.
Genetic Variation
Y. Guan, Dunham, M. J., Troyanskaya, O. G., and Caudy, A. A.,
“Comparative gene expression between two yeast species.”,
BMC Genomics, vol. 14, p. 33, 2013.
Genome, Fungal
A. A. Caudy, Guan, Y., Jia, Y., Hansen, C., DeSevo, C., Hayes, A. P., Agee, J., Alvarez-Dominguez, J. R., Arellano, H., Barrett, D., Bauerle, C., Bisaria, N., Bradley, P. H., J Breunig, S., Bush, E., Cappel, D., Capra, E., Chen, W., Clore, J., Combs, P. A., Doucette, C., Demuren, O., Fellowes, P., Freeman, S., Frenkel, E., Gadala-Maria, D., Gawande, R., Glass, D., Grossberg, S., Gupta, A., Hammonds-Odie, L., Hoisos, A., Hsi, J., Hsu, Y. - H. Huang, Inukai, S., Karczewski, K. J., Ke, X., Kojima, M., Leachman, S., Lieber, D., Liebowitz, A., Liu, J., Liu, Y., Martin, T., Mena, J., Mendoza, R., Myhrvold, C., Millian, C., Pfau, S., Raj, S., Rich, M., Rokicki, J., Rounds, W., Salazar, M., Salesi, M., Sharma, R., Silverman, S., Singer, C., Sinha, S., Staller, M., Stern, P., Tang, H., Weeks, S., Weidmann, M., Wolf, A., Young, C., Yuan, J., Crutchfield, C., McClean, M., Murphy, C. T., Llinás, M., Botstein, D., Troyanskaya, O. G., and Dunham, M. J.,
“A new system for comparative functional genomics of Saccharomyces yeasts.”,
Genetics, vol. 195, no. 1, pp. 275-87, 2013.
Glyceraldehyde 3-Phosphate
Y. - F. Xu, Létisse, F., Absalan, F., Lu, W., Kuznetsova, E., Brown, G., Caudy, A. A., Yakunin, A. F., Broach, J. R., and Rabinowitz, J. D.,
“Nucleotide degradation and ribose salvage in yeast.”,
Mol Syst Biol, vol. 9, p. 665, 2013.
Heat-Shock Response
P. A. Gibney, Lu, C., Caudy, A. A., Hess, D. C., and Botstein, D.,
“Yeast metabolic and signaling genes are required for heat-shock survival and have little overlap with the heat-induced genes.”,
Proc Natl Acad Sci U S A, vol. 110, no. 46, pp. E4393-402, 2013.
High-Throughput Nucleotide Sequencing
P. A. Gibney, Lu, C., Caudy, A. A., Hess, D. C., and Botstein, D.,
“Yeast metabolic and signaling genes are required for heat-shock survival and have little overlap with the heat-induced genes.”,
Proc Natl Acad Sci U S A, vol. 110, no. 46, pp. E4393-402, 2013.
Humans
Z. Khan, Bloom, J. S., Amini, S., Singh, M., Perlman, D. H., Caudy, A. A., and Kruglyak, L.,
“Quantitative measurement of allele-specific protein expression in a diploid yeast hybrid by LC-MS.”,
Mol Syst Biol, vol. 8, p. 602, 2012.
Isotope Labeling
Z. Khan, Amini, S., Bloom, J. S., Ruse, C., Caudy, A. A., Kruglyak, L., Singh, M., Perlman, D. H., and Tavazoie, S.,
“Accurate proteome-wide protein quantification from high-resolution 15N mass spectra.”,
Genome Biol, vol. 12, no. 12, p. R122, 2011.
Kinetics
W. Lu, Clasquin, M. F., Melamud, E., Amador-Noguez, D., Caudy, A. A., and Rabinowitz, J. D.,
“Metabolomic analysis via reversed-phase ion-pairing liquid chromatography coupled to a stand alone orbitrap mass spectrometer.”,
Anal Chem, vol. 82, no. 8, pp. 3212-21, 2010.
Mass Spectrometry
Z. Khan, Amini, S., Bloom, J. S., Ruse, C., Caudy, A. A., Kruglyak, L., Singh, M., Perlman, D. H., and Tavazoie, S.,
“Accurate proteome-wide protein quantification from high-resolution 15N mass spectra.”,
Genome Biol, vol. 12, no. 12, p. R122, 2011.
Z. Khan, Bloom, J. S., Amini, S., Singh, M., Perlman, D. H., Caudy, A. A., and Kruglyak, L.,
“Quantitative measurement of allele-specific protein expression in a diploid yeast hybrid by LC-MS.”,
Mol Syst Biol, vol. 8, p. 602, 2012.
Metabolic Networks and Pathways
P. A. Gibney, Lu, C., Caudy, A. A., Hess, D. C., and Botstein, D.,
“Yeast metabolic and signaling genes are required for heat-shock survival and have little overlap with the heat-induced genes.”,
Proc Natl Acad Sci U S A, vol. 110, no. 46, pp. E4393-402, 2013.
Metabolome
W. Lu, Clasquin, M. F., Melamud, E., Amador-Noguez, D., Caudy, A. A., and Rabinowitz, J. D.,
“Metabolomic analysis via reversed-phase ion-pairing liquid chromatography coupled to a stand alone orbitrap mass spectrometer.”,
Anal Chem, vol. 82, no. 8, pp. 3212-21, 2010.
Metabolomics
W. Lu, Clasquin, M. F., Melamud, E., Amador-Noguez, D., Caudy, A. A., and Rabinowitz, J. D.,
“Metabolomic analysis via reversed-phase ion-pairing liquid chromatography coupled to a stand alone orbitrap mass spectrometer.”,
Anal Chem, vol. 82, no. 8, pp. 3212-21, 2010.
Mice
Y. Guan, Myers, C. L., Hess, D. C., Barutcuoglu, Z., Caudy, A. A., and Troyanskaya, O. G.,
“Predicting gene function in a hierarchical context with an ensemble of classifiers.”,
Genome Biol, vol. 9 Suppl 1, p. S3, 2008.
Mitochondria
M. A. Hibbs, Myers, C. L., Huttenhower, C., Hess, D. C., Li, K., Caudy, A. A., and Troyanskaya, O. G.,
“Directing experimental biology: a case study in mitochondrial biogenesis.”,
PLoS Comput Biol, vol. 5, no. 3, p. e1000322, 2009.
D. C. Hess, Myers, C. L., Huttenhower, C., Hibbs, M. A., Hayes, A. P., Paw, J., Clore, J. J., Mendoza, R. M., San Luis, B., Nislow, C., Giaever, G., Costanzo, M., Troyanskaya, O. G., and Caudy, A. A.,
“Computationally driven, quantitative experiments discover genes required for mitochondrial biogenesis.”,
PLoS Genet, vol. 5, no. 3, p. e1000407, 2009.
C. Huttenhower, Hibbs, M. A., Myers, C. L., Caudy, A. A., Hess, D. C., and Troyanskaya, O. G.,
“The impact of incomplete knowledge on evaluation: an experimental benchmark for protein function prediction.”,
Bioinformatics, vol. 25, no. 18, pp. 2404-10, 2009.
Mitochondrial Proteins
M. A. Hibbs, Myers, C. L., Huttenhower, C., Hess, D. C., Li, K., Caudy, A. A., and Troyanskaya, O. G.,
“Directing experimental biology: a case study in mitochondrial biogenesis.”,
PLoS Comput Biol, vol. 5, no. 3, p. e1000322, 2009.
Y. Guan, Myers, C. L., Hess, D. C., Barutcuoglu, Z., Caudy, A. A., and Troyanskaya, O. G.,
“Predicting gene function in a hierarchical context with an ensemble of classifiers.”,
Genome Biol, vol. 9 Suppl 1, p. S3, 2008.
D. C. Hess, Myers, C. L., Huttenhower, C., Hibbs, M. A., Hayes, A. P., Paw, J., Clore, J. J., Mendoza, R. M., San Luis, B., Nislow, C., Giaever, G., Costanzo, M., Troyanskaya, O. G., and Caudy, A. A.,
“Computationally driven, quantitative experiments discover genes required for mitochondrial biogenesis.”,
PLoS Genet, vol. 5, no. 3, p. e1000407, 2009.
Models, Biological
M. A. Hibbs, Myers, C. L., Huttenhower, C., Hess, D. C., Li, K., Caudy, A. A., and Troyanskaya, O. G.,
“Directing experimental biology: a case study in mitochondrial biogenesis.”,
PLoS Comput Biol, vol. 5, no. 3, p. e1000322, 2009.
E. M. Airoldi, Huttenhower, C., Gresham, D., Lu, C., Caudy, A. A., Dunham, M. J., Broach, J. R., Botstein, D., and Troyanskaya, O. G.,
“Predicting cellular growth from gene expression signatures.”,
PLoS Comput Biol, vol. 5, no. 1, p. e1000257, 2009.
Models, Molecular
M. F. Clasquin, Melamud, E., Singer, A., Gooding, J. R., Xu, X., Dong, A., Cui, H., Campagna, S. R., Savchenko, A., Yakunin, A. F., Rabinowitz, J. D., and Caudy, A. A.,
“Riboneogenesis in yeast.”,
Cell, vol. 145, no. 6, pp. 969-80, 2011.
Molecular Sequence Annotation
A. A. Caudy, Guan, Y., Jia, Y., Hansen, C., DeSevo, C., Hayes, A. P., Agee, J., Alvarez-Dominguez, J. R., Arellano, H., Barrett, D., Bauerle, C., Bisaria, N., Bradley, P. H., J Breunig, S., Bush, E., Cappel, D., Capra, E., Chen, W., Clore, J., Combs, P. A., Doucette, C., Demuren, O., Fellowes, P., Freeman, S., Frenkel, E., Gadala-Maria, D., Gawande, R., Glass, D., Grossberg, S., Gupta, A., Hammonds-Odie, L., Hoisos, A., Hsi, J., Hsu, Y. - H. Huang, Inukai, S., Karczewski, K. J., Ke, X., Kojima, M., Leachman, S., Lieber, D., Liebowitz, A., Liu, J., Liu, Y., Martin, T., Mena, J., Mendoza, R., Myhrvold, C., Millian, C., Pfau, S., Raj, S., Rich, M., Rokicki, J., Rounds, W., Salazar, M., Salesi, M., Sharma, R., Silverman, S., Singer, C., Sinha, S., Staller, M., Stern, P., Tang, H., Weeks, S., Weidmann, M., Wolf, A., Young, C., Yuan, J., Crutchfield, C., McClean, M., Murphy, C. T., Llinás, M., Botstein, D., Troyanskaya, O. G., and Dunham, M. J.,
“A new system for comparative functional genomics of Saccharomyces yeasts.”,
Genetics, vol. 195, no. 1, pp. 275-87, 2013.
P. A. Gibney, Lu, C., Caudy, A. A., Hess, D. C., and Botstein, D.,
“Yeast metabolic and signaling genes are required for heat-shock survival and have little overlap with the heat-induced genes.”,
Proc Natl Acad Sci U S A, vol. 110, no. 46, pp. E4393-402, 2013.
Molecular Sequence Data
Z. Khan, Amini, S., Bloom, J. S., Ruse, C., Caudy, A. A., Kruglyak, L., Singh, M., Perlman, D. H., and Tavazoie, S.,
“Accurate proteome-wide protein quantification from high-resolution 15N mass spectra.”,
Genome Biol, vol. 12, no. 12, p. R122, 2011.
Mutant Proteins
D. C. Hess, Myers, C. L., Huttenhower, C., Hibbs, M. A., Hayes, A. P., Paw, J., Clore, J. J., Mendoza, R. M., San Luis, B., Nislow, C., Giaever, G., Costanzo, M., Troyanskaya, O. G., and Caudy, A. A.,
“Computationally driven, quantitative experiments discover genes required for mitochondrial biogenesis.”,
PLoS Genet, vol. 5, no. 3, p. e1000407, 2009.
Mutation
D. C. Hess, Myers, C. L., Huttenhower, C., Hibbs, M. A., Hayes, A. P., Paw, J., Clore, J. J., Mendoza, R. M., San Luis, B., Nislow, C., Giaever, G., Costanzo, M., Troyanskaya, O. G., and Caudy, A. A.,
“Computationally driven, quantitative experiments discover genes required for mitochondrial biogenesis.”,
PLoS Genet, vol. 5, no. 3, p. e1000407, 2009.
N-Glycosyl Hydrolases
Y. - F. Xu, Létisse, F., Absalan, F., Lu, W., Kuznetsova, E., Brown, G., Caudy, A. A., Yakunin, A. F., Broach, J. R., and Rabinowitz, J. D.,
“Nucleotide degradation and ribose salvage in yeast.”,
Mol Syst Biol, vol. 9, p. 665, 2013.
NADP
Y. - F. Xu, Létisse, F., Absalan, F., Lu, W., Kuznetsova, E., Brown, G., Caudy, A. A., Yakunin, A. F., Broach, J. R., and Rabinowitz, J. D.,
“Nucleotide degradation and ribose salvage in yeast.”,
Mol Syst Biol, vol. 9, p. 665, 2013.
Nitrogen Isotopes
Z. Khan, Amini, S., Bloom, J. S., Ruse, C., Caudy, A. A., Kruglyak, L., Singh, M., Perlman, D. H., and Tavazoie, S.,
“Accurate proteome-wide protein quantification from high-resolution 15N mass spectra.”,
Genome Biol, vol. 12, no. 12, p. R122, 2011.
Nucleotides
Y. - F. Xu, Létisse, F., Absalan, F., Lu, W., Kuznetsova, E., Brown, G., Caudy, A. A., Yakunin, A. F., Broach, J. R., and Rabinowitz, J. D.,
“Nucleotide degradation and ribose salvage in yeast.”,
Mol Syst Biol, vol. 9, p. 665, 2013.
Oligonucleotide Array Sequence Analysis
J. S. Bloom, Khan, Z., Kruglyak, L., Singh, M., and Caudy, A. A.,
“Measuring differential gene expression by short read sequencing: quantitative comparison to 2-channel gene expression microarrays.”,
BMC Genomics, vol. 10, p. 221, 2009.
Oxidative Stress
A. A. Caudy, Guan, Y., Jia, Y., Hansen, C., DeSevo, C., Hayes, A. P., Agee, J., Alvarez-Dominguez, J. R., Arellano, H., Barrett, D., Bauerle, C., Bisaria, N., Bradley, P. H., J Breunig, S., Bush, E., Cappel, D., Capra, E., Chen, W., Clore, J., Combs, P. A., Doucette, C., Demuren, O., Fellowes, P., Freeman, S., Frenkel, E., Gadala-Maria, D., Gawande, R., Glass, D., Grossberg, S., Gupta, A., Hammonds-Odie, L., Hoisos, A., Hsi, J., Hsu, Y. - H. Huang, Inukai, S., Karczewski, K. J., Ke, X., Kojima, M., Leachman, S., Lieber, D., Liebowitz, A., Liu, J., Liu, Y., Martin, T., Mena, J., Mendoza, R., Myhrvold, C., Millian, C., Pfau, S., Raj, S., Rich, M., Rokicki, J., Rounds, W., Salazar, M., Salesi, M., Sharma, R., Silverman, S., Singer, C., Sinha, S., Staller, M., Stern, P., Tang, H., Weeks, S., Weidmann, M., Wolf, A., Young, C., Yuan, J., Crutchfield, C., McClean, M., Murphy, C. T., Llinás, M., Botstein, D., Troyanskaya, O. G., and Dunham, M. J.,
“A new system for comparative functional genomics of Saccharomyces yeasts.”,
Genetics, vol. 195, no. 1, pp. 275-87, 2013.
Pentose Phosphate Pathway
M. F. Clasquin, Melamud, E., Singer, A., Gooding, J. R., Xu, X., Dong, A., Cui, H., Campagna, S. R., Savchenko, A., Yakunin, A. F., Rabinowitz, J. D., and Caudy, A. A.,
“Riboneogenesis in yeast.”,
Cell, vol. 145, no. 6, pp. 969-80, 2011.
Y. - F. Xu, Létisse, F., Absalan, F., Lu, W., Kuznetsova, E., Brown, G., Caudy, A. A., Yakunin, A. F., Broach, J. R., and Rabinowitz, J. D.,
“Nucleotide degradation and ribose salvage in yeast.”,
Mol Syst Biol, vol. 9, p. 665, 2013.
Phosphoric Monoester Hydrolases
M. F. Clasquin, Melamud, E., Singer, A., Gooding, J. R., Xu, X., Dong, A., Cui, H., Campagna, S. R., Savchenko, A., Yakunin, A. F., Rabinowitz, J. D., and Caudy, A. A.,
“Riboneogenesis in yeast.”,
Cell, vol. 145, no. 6, pp. 969-80, 2011.
Protein-Serine-Threonine Kinases
Y. - F. Xu, Létisse, F., Absalan, F., Lu, W., Kuznetsova, E., Brown, G., Caudy, A. A., Yakunin, A. F., Broach, J. R., and Rabinowitz, J. D.,
“Nucleotide degradation and ribose salvage in yeast.”,
Mol Syst Biol, vol. 9, p. 665, 2013.
Proteins
Y. Guan, Myers, C. L., Hess, D. C., Barutcuoglu, Z., Caudy, A. A., and Troyanskaya, O. G.,
“Predicting gene function in a hierarchical context with an ensemble of classifiers.”,
Genome Biol, vol. 9 Suppl 1, p. S3, 2008.
D. C. Hess, Myers, C. L., Huttenhower, C., Hibbs, M. A., Hayes, A. P., Paw, J., Clore, J. J., Mendoza, R. M., San Luis, B., Nislow, C., Giaever, G., Costanzo, M., Troyanskaya, O. G., and Caudy, A. A.,
“Computationally driven, quantitative experiments discover genes required for mitochondrial biogenesis.”,
PLoS Genet, vol. 5, no. 3, p. e1000407, 2009.
C. Huttenhower, Hibbs, M. A., Myers, C. L., Caudy, A. A., Hess, D. C., and Troyanskaya, O. G.,
“The impact of incomplete knowledge on evaluation: an experimental benchmark for protein function prediction.”,
Bioinformatics, vol. 25, no. 18, pp. 2404-10, 2009.
Proteome
Z. Khan, Amini, S., Bloom, J. S., Ruse, C., Caudy, A. A., Kruglyak, L., Singh, M., Perlman, D. H., and Tavazoie, S.,
“Accurate proteome-wide protein quantification from high-resolution 15N mass spectra.”,
Genome Biol, vol. 12, no. 12, p. R122, 2011.
E. M. Airoldi, Huttenhower, C., Gresham, D., Lu, C., Caudy, A. A., Dunham, M. J., Broach, J. R., Botstein, D., and Troyanskaya, O. G.,
“Predicting cellular growth from gene expression signatures.”,
PLoS Comput Biol, vol. 5, no. 1, p. e1000257, 2009.
Proteomics
D. C. Hess, Myers, C. L., Huttenhower, C., Hibbs, M. A., Hayes, A. P., Paw, J., Clore, J. J., Mendoza, R. M., San Luis, B., Nislow, C., Giaever, G., Costanzo, M., Troyanskaya, O. G., and Caudy, A. A.,
“Computationally driven, quantitative experiments discover genes required for mitochondrial biogenesis.”,
PLoS Genet, vol. 5, no. 3, p. e1000407, 2009.
Z. Khan, Bloom, J. S., Amini, S., Singh, M., Perlman, D. H., Caudy, A. A., and Kruglyak, L.,
“Quantitative measurement of allele-specific protein expression in a diploid yeast hybrid by LC-MS.”,
Mol Syst Biol, vol. 8, p. 602, 2012.
Z. Khan, Amini, S., Bloom, J. S., Ruse, C., Caudy, A. A., Kruglyak, L., Singh, M., Perlman, D. H., and Tavazoie, S.,
“Accurate proteome-wide protein quantification from high-resolution 15N mass spectra.”,
Genome Biol, vol. 12, no. 12, p. R122, 2011.
Purine-Nucleoside Phosphorylase
Y. - F. Xu, Létisse, F., Absalan, F., Lu, W., Kuznetsova, E., Brown, G., Caudy, A. A., Yakunin, A. F., Broach, J. R., and Rabinowitz, J. D.,
“Nucleotide degradation and ribose salvage in yeast.”,
Mol Syst Biol, vol. 9, p. 665, 2013.
Pyroglutamate Hydrolase
W. Lu, Clasquin, M. F., Melamud, E., Amador-Noguez, D., Caudy, A. A., and Rabinowitz, J. D.,
“Metabolomic analysis via reversed-phase ion-pairing liquid chromatography coupled to a stand alone orbitrap mass spectrometer.”,
Anal Chem, vol. 82, no. 8, pp. 3212-21, 2010.
Regression Analysis
Z. Khan, Bloom, J. S., Amini, S., Singh, M., Perlman, D. H., Caudy, A. A., and Kruglyak, L.,
“Quantitative measurement of allele-specific protein expression in a diploid yeast hybrid by LC-MS.”,
Mol Syst Biol, vol. 8, p. 602, 2012.
Research Design
M. A. Hibbs, Myers, C. L., Huttenhower, C., Hess, D. C., Li, K., Caudy, A. A., and Troyanskaya, O. G.,
“Directing experimental biology: a case study in mitochondrial biogenesis.”,
PLoS Comput Biol, vol. 5, no. 3, p. e1000322, 2009.
Ribose
Y. - F. Xu, Létisse, F., Absalan, F., Lu, W., Kuznetsova, E., Brown, G., Caudy, A. A., Yakunin, A. F., Broach, J. R., and Rabinowitz, J. D.,
“Nucleotide degradation and ribose salvage in yeast.”,
Mol Syst Biol, vol. 9, p. 665, 2013.
Ribosemonophosphates
M. F. Clasquin, Melamud, E., Singer, A., Gooding, J. R., Xu, X., Dong, A., Cui, H., Campagna, S. R., Savchenko, A., Yakunin, A. F., Rabinowitz, J. D., and Caudy, A. A.,
“Riboneogenesis in yeast.”,
Cell, vol. 145, no. 6, pp. 969-80, 2011.
Saccharomyces
Z. Khan, Bloom, J. S., Amini, S., Singh, M., Perlman, D. H., Caudy, A. A., and Kruglyak, L.,
“Quantitative measurement of allele-specific protein expression in a diploid yeast hybrid by LC-MS.”,
Mol Syst Biol, vol. 8, p. 602, 2012.
A. A. Caudy, Guan, Y., Jia, Y., Hansen, C., DeSevo, C., Hayes, A. P., Agee, J., Alvarez-Dominguez, J. R., Arellano, H., Barrett, D., Bauerle, C., Bisaria, N., Bradley, P. H., J Breunig, S., Bush, E., Cappel, D., Capra, E., Chen, W., Clore, J., Combs, P. A., Doucette, C., Demuren, O., Fellowes, P., Freeman, S., Frenkel, E., Gadala-Maria, D., Gawande, R., Glass, D., Grossberg, S., Gupta, A., Hammonds-Odie, L., Hoisos, A., Hsi, J., Hsu, Y. - H. Huang, Inukai, S., Karczewski, K. J., Ke, X., Kojima, M., Leachman, S., Lieber, D., Liebowitz, A., Liu, J., Liu, Y., Martin, T., Mena, J., Mendoza, R., Myhrvold, C., Millian, C., Pfau, S., Raj, S., Rich, M., Rokicki, J., Rounds, W., Salazar, M., Salesi, M., Sharma, R., Silverman, S., Singer, C., Sinha, S., Staller, M., Stern, P., Tang, H., Weeks, S., Weidmann, M., Wolf, A., Young, C., Yuan, J., Crutchfield, C., McClean, M., Murphy, C. T., Llinás, M., Botstein, D., Troyanskaya, O. G., and Dunham, M. J.,
“A new system for comparative functional genomics of Saccharomyces yeasts.”,
Genetics, vol. 195, no. 1, pp. 275-87, 2013.
Saccharomyces cerevisiae
M. A. Hibbs, Myers, C. L., Huttenhower, C., Hess, D. C., Li, K., Caudy, A. A., and Troyanskaya, O. G.,
“Directing experimental biology: a case study in mitochondrial biogenesis.”,
PLoS Comput Biol, vol. 5, no. 3, p. e1000322, 2009.
Y. Guan, Myers, C. L., Hess, D. C., Barutcuoglu, Z., Caudy, A. A., and Troyanskaya, O. G.,
“Predicting gene function in a hierarchical context with an ensemble of classifiers.”,
Genome Biol, vol. 9 Suppl 1, p. S3, 2008.
M. Costanzo, VanderSluis, B., Koch, E. N., Baryshnikova, A., Pons, C., Tan, G., Wang, W., Usaj, M., Hanchard, J., Lee, S. D., Pelechano, V., Styles, E. B., Billmann, M., van Leeuwen, J., van Dyk, N., Lin, Z. - Y., Kuzmin, E., Nelson, J., Piotrowski, J. S., Srikumar, T., Bahr, S., Chen, Y., Deshpande, R., Kurat, C. F., Li, S. C., Li, Z., Usaj, M. Mattiazzi, Okada, H., Pascoe, N., San Luis, B. - J., Sharifpoor, S., Shuteriqi, E., Simpkins, S. W., Snider, J., Suresh, H. Garadi, Tan, Y., Zhu, H., Malod-Dognin, N., Janjic, V., Przulj, N., Troyanskaya, O. G., Stagljar, I., Xia, T., Ohya, Y., Gingras, A. - C., Raught, B., Boutros, M., Steinmetz, L. M., Moore, C. L., Rosebrock, A. P., Caudy, A. A., Myers, C. L., Andrews, B., and Boone, C.,
“A global genetic interaction network maps a wiring diagram of cellular function.”,
Science, vol. 353, no. 6306, 2016.
D. C. Hess, Myers, C. L., Huttenhower, C., Hibbs, M. A., Hayes, A. P., Paw, J., Clore, J. J., Mendoza, R. M., San Luis, B., Nislow, C., Giaever, G., Costanzo, M., Troyanskaya, O. G., and Caudy, A. A.,
“Computationally driven, quantitative experiments discover genes required for mitochondrial biogenesis.”,
PLoS Genet, vol. 5, no. 3, p. e1000407, 2009.
W. Lu, Clasquin, M. F., Melamud, E., Amador-Noguez, D., Caudy, A. A., and Rabinowitz, J. D.,
“Metabolomic analysis via reversed-phase ion-pairing liquid chromatography coupled to a stand alone orbitrap mass spectrometer.”,
Anal Chem, vol. 82, no. 8, pp. 3212-21, 2010.
E. M. Airoldi, Huttenhower, C., Gresham, D., Lu, C., Caudy, A. A., Dunham, M. J., Broach, J. R., Botstein, D., and Troyanskaya, O. G.,
“Predicting cellular growth from gene expression signatures.”,
PLoS Comput Biol, vol. 5, no. 1, p. e1000257, 2009.
P. A. Gibney, Lu, C., Caudy, A. A., Hess, D. C., and Botstein, D.,
“Yeast metabolic and signaling genes are required for heat-shock survival and have little overlap with the heat-induced genes.”,
Proc Natl Acad Sci U S A, vol. 110, no. 46, pp. E4393-402, 2013.
M. F. Clasquin, Melamud, E., Singer, A., Gooding, J. R., Xu, X., Dong, A., Cui, H., Campagna, S. R., Savchenko, A., Yakunin, A. F., Rabinowitz, J. D., and Caudy, A. A.,
“Riboneogenesis in yeast.”,
Cell, vol. 145, no. 6, pp. 969-80, 2011.
J. S. Bloom, Khan, Z., Kruglyak, L., Singh, M., and Caudy, A. A.,
“Measuring differential gene expression by short read sequencing: quantitative comparison to 2-channel gene expression microarrays.”,
BMC Genomics, vol. 10, p. 221, 2009.
Y. - F. Xu, Létisse, F., Absalan, F., Lu, W., Kuznetsova, E., Brown, G., Caudy, A. A., Yakunin, A. F., Broach, J. R., and Rabinowitz, J. D.,
“Nucleotide degradation and ribose salvage in yeast.”,
Mol Syst Biol, vol. 9, p. 665, 2013.
Y. Guan, Dunham, M. J., Troyanskaya, O. G., and Caudy, A. A.,
“Comparative gene expression between two yeast species.”,
BMC Genomics, vol. 14, p. 33, 2013.
Z. Khan, Bloom, J. S., Amini, S., Singh, M., Perlman, D. H., Caudy, A. A., and Kruglyak, L.,
“Quantitative measurement of allele-specific protein expression in a diploid yeast hybrid by LC-MS.”,
Mol Syst Biol, vol. 8, p. 602, 2012.
C. Huttenhower, Hibbs, M. A., Myers, C. L., Caudy, A. A., Hess, D. C., and Troyanskaya, O. G.,
“The impact of incomplete knowledge on evaluation: an experimental benchmark for protein function prediction.”,
Bioinformatics, vol. 25, no. 18, pp. 2404-10, 2009.
Saccharomyces cerevisiae Proteins
M. A. Hibbs, Myers, C. L., Huttenhower, C., Hess, D. C., Li, K., Caudy, A. A., and Troyanskaya, O. G.,
“Directing experimental biology: a case study in mitochondrial biogenesis.”,
PLoS Comput Biol, vol. 5, no. 3, p. e1000322, 2009.
M. Costanzo, VanderSluis, B., Koch, E. N., Baryshnikova, A., Pons, C., Tan, G., Wang, W., Usaj, M., Hanchard, J., Lee, S. D., Pelechano, V., Styles, E. B., Billmann, M., van Leeuwen, J., van Dyk, N., Lin, Z. - Y., Kuzmin, E., Nelson, J., Piotrowski, J. S., Srikumar, T., Bahr, S., Chen, Y., Deshpande, R., Kurat, C. F., Li, S. C., Li, Z., Usaj, M. Mattiazzi, Okada, H., Pascoe, N., San Luis, B. - J., Sharifpoor, S., Shuteriqi, E., Simpkins, S. W., Snider, J., Suresh, H. Garadi, Tan, Y., Zhu, H., Malod-Dognin, N., Janjic, V., Przulj, N., Troyanskaya, O. G., Stagljar, I., Xia, T., Ohya, Y., Gingras, A. - C., Raught, B., Boutros, M., Steinmetz, L. M., Moore, C. L., Rosebrock, A. P., Caudy, A. A., Myers, C. L., Andrews, B., and Boone, C.,
“A global genetic interaction network maps a wiring diagram of cellular function.”,
Science, vol. 353, no. 6306, 2016.
Y. Guan, Myers, C. L., Hess, D. C., Barutcuoglu, Z., Caudy, A. A., and Troyanskaya, O. G.,
“Predicting gene function in a hierarchical context with an ensemble of classifiers.”,
Genome Biol, vol. 9 Suppl 1, p. S3, 2008.
E. M. Airoldi, Huttenhower, C., Gresham, D., Lu, C., Caudy, A. A., Dunham, M. J., Broach, J. R., Botstein, D., and Troyanskaya, O. G.,
“Predicting cellular growth from gene expression signatures.”,
PLoS Comput Biol, vol. 5, no. 1, p. e1000257, 2009.
Y. - F. Xu, Létisse, F., Absalan, F., Lu, W., Kuznetsova, E., Brown, G., Caudy, A. A., Yakunin, A. F., Broach, J. R., and Rabinowitz, J. D.,
“Nucleotide degradation and ribose salvage in yeast.”,
Mol Syst Biol, vol. 9, p. 665, 2013.
Z. Khan, Bloom, J. S., Amini, S., Singh, M., Perlman, D. H., Caudy, A. A., and Kruglyak, L.,
“Quantitative measurement of allele-specific protein expression in a diploid yeast hybrid by LC-MS.”,
Mol Syst Biol, vol. 8, p. 602, 2012.
Sensitivity and Specificity
Z. Khan, Amini, S., Bloom, J. S., Ruse, C., Caudy, A. A., Kruglyak, L., Singh, M., Perlman, D. H., and Tavazoie, S.,
“Accurate proteome-wide protein quantification from high-resolution 15N mass spectra.”,
Genome Biol, vol. 12, no. 12, p. R122, 2011.
Sequence Alignment
J. S. Bloom, Khan, Z., Kruglyak, L., Singh, M., and Caudy, A. A.,
“Measuring differential gene expression by short read sequencing: quantitative comparison to 2-channel gene expression microarrays.”,
BMC Genomics, vol. 10, p. 221, 2009.
Sequence Analysis, DNA
J. S. Bloom, Khan, Z., Kruglyak, L., Singh, M., and Caudy, A. A.,
“Measuring differential gene expression by short read sequencing: quantitative comparison to 2-channel gene expression microarrays.”,
BMC Genomics, vol. 10, p. 221, 2009.
Signal Transduction
M. A. Hibbs, Myers, C. L., Huttenhower, C., Hess, D. C., Li, K., Caudy, A. A., and Troyanskaya, O. G.,
“Directing experimental biology: a case study in mitochondrial biogenesis.”,
PLoS Comput Biol, vol. 5, no. 3, p. e1000322, 2009.
P. A. Gibney, Lu, C., Caudy, A. A., Hess, D. C., and Botstein, D.,
“Yeast metabolic and signaling genes are required for heat-shock survival and have little overlap with the heat-induced genes.”,
Proc Natl Acad Sci U S A, vol. 110, no. 46, pp. E4393-402, 2013.
Y. - F. Xu, Létisse, F., Absalan, F., Lu, W., Kuznetsova, E., Brown, G., Caudy, A. A., Yakunin, A. F., Broach, J. R., and Rabinowitz, J. D.,
“Nucleotide degradation and ribose salvage in yeast.”,
Mol Syst Biol, vol. 9, p. 665, 2013.
Software
Z. Khan, Amini, S., Bloom, J. S., Ruse, C., Caudy, A. A., Kruglyak, L., Singh, M., Perlman, D. H., and Tavazoie, S.,
“Accurate proteome-wide protein quantification from high-resolution 15N mass spectra.”,
Genome Biol, vol. 12, no. 12, p. R122, 2011.
Species Specificity
Y. Guan, Dunham, M. J., Troyanskaya, O. G., and Caudy, A. A.,
“Comparative gene expression between two yeast species.”,
BMC Genomics, vol. 14, p. 33, 2013.
Z. Khan, Bloom, J. S., Amini, S., Singh, M., Perlman, D. H., Caudy, A. A., and Kruglyak, L.,
“Quantitative measurement of allele-specific protein expression in a diploid yeast hybrid by LC-MS.”,
Mol Syst Biol, vol. 8, p. 602, 2012.
Spectrometry, Mass, Electrospray Ionization
W. Lu, Clasquin, M. F., Melamud, E., Amador-Noguez, D., Caudy, A. A., and Rabinowitz, J. D.,
“Metabolomic analysis via reversed-phase ion-pairing liquid chromatography coupled to a stand alone orbitrap mass spectrometer.”,
Anal Chem, vol. 82, no. 8, pp. 3212-21, 2010.
Statistics as Topic
Y. Guan, Dunham, M. J., Troyanskaya, O. G., and Caudy, A. A.,
“Comparative gene expression between two yeast species.”,
BMC Genomics, vol. 14, p. 33, 2013.
Stress, Physiological
Y. - F. Xu, Létisse, F., Absalan, F., Lu, W., Kuznetsova, E., Brown, G., Caudy, A. A., Yakunin, A. F., Broach, J. R., and Rabinowitz, J. D.,
“Nucleotide degradation and ribose salvage in yeast.”,
Mol Syst Biol, vol. 9, p. 665, 2013.
Sugar Phosphates
Y. - F. Xu, Létisse, F., Absalan, F., Lu, W., Kuznetsova, E., Brown, G., Caudy, A. A., Yakunin, A. F., Broach, J. R., and Rabinowitz, J. D.,
“Nucleotide degradation and ribose salvage in yeast.”,
Mol Syst Biol, vol. 9, p. 665, 2013.
Systems Biology
P. A. Gibney, Lu, C., Caudy, A. A., Hess, D. C., and Botstein, D.,
“Yeast metabolic and signaling genes are required for heat-shock survival and have little overlap with the heat-induced genes.”,
Proc Natl Acad Sci U S A, vol. 110, no. 46, pp. E4393-402, 2013.
Transaldolase
Y. - F. Xu, Létisse, F., Absalan, F., Lu, W., Kuznetsova, E., Brown, G., Caudy, A. A., Yakunin, A. F., Broach, J. R., and Rabinowitz, J. D.,
“Nucleotide degradation and ribose salvage in yeast.”,
Mol Syst Biol, vol. 9, p. 665, 2013.