Transaldolase
Y. - F. Xu, Létisse, F., Absalan, F., Lu, W., Kuznetsova, E., Brown, G., Caudy, A. A., Yakunin, A. F., Broach, J. R., and Rabinowitz, J. D.,
“Nucleotide degradation and ribose salvage in yeast.”,
Mol Syst Biol, vol. 9, p. 665, 2013.
Systems Biology
P. A. Gibney, Lu, C., Caudy, A. A., Hess, D. C., and Botstein, D.,
“Yeast metabolic and signaling genes are required for heat-shock survival and have little overlap with the heat-induced genes.”,
Proc Natl Acad Sci U S A, vol. 110, no. 46, pp. E4393-402, 2013.
Sugar Phosphates
Y. - F. Xu, Létisse, F., Absalan, F., Lu, W., Kuznetsova, E., Brown, G., Caudy, A. A., Yakunin, A. F., Broach, J. R., and Rabinowitz, J. D.,
“Nucleotide degradation and ribose salvage in yeast.”,
Mol Syst Biol, vol. 9, p. 665, 2013.
Stress, Physiological
Y. - F. Xu, Létisse, F., Absalan, F., Lu, W., Kuznetsova, E., Brown, G., Caudy, A. A., Yakunin, A. F., Broach, J. R., and Rabinowitz, J. D.,
“Nucleotide degradation and ribose salvage in yeast.”,
Mol Syst Biol, vol. 9, p. 665, 2013.
Statistics as Topic
Y. Guan, Dunham, M. J., Troyanskaya, O. G., and Caudy, A. A.,
“Comparative gene expression between two yeast species.”,
BMC Genomics, vol. 14, p. 33, 2013.
Spectrometry, Mass, Electrospray Ionization
W. Lu, Clasquin, M. F., Melamud, E., Amador-Noguez, D., Caudy, A. A., and Rabinowitz, J. D.,
“Metabolomic analysis via reversed-phase ion-pairing liquid chromatography coupled to a stand alone orbitrap mass spectrometer.”,
Anal Chem, vol. 82, no. 8, pp. 3212-21, 2010.
Species Specificity
Y. Guan, Dunham, M. J., Troyanskaya, O. G., and Caudy, A. A.,
“Comparative gene expression between two yeast species.”,
BMC Genomics, vol. 14, p. 33, 2013.
Z. Khan, Bloom, J. S., Amini, S., Singh, M., Perlman, D. H., Caudy, A. A., and Kruglyak, L.,
“Quantitative measurement of allele-specific protein expression in a diploid yeast hybrid by LC-MS.”,
Mol Syst Biol, vol. 8, p. 602, 2012.
Software
Z. Khan, Amini, S., Bloom, J. S., Ruse, C., Caudy, A. A., Kruglyak, L., Singh, M., Perlman, D. H., and Tavazoie, S.,
“Accurate proteome-wide protein quantification from high-resolution 15N mass spectra.”,
Genome Biol, vol. 12, no. 12, p. R122, 2011.
Signal Transduction
M. A. Hibbs, Myers, C. L., Huttenhower, C., Hess, D. C., Li, K., Caudy, A. A., and Troyanskaya, O. G.,
“Directing experimental biology: a case study in mitochondrial biogenesis.”,
PLoS Comput Biol, vol. 5, no. 3, p. e1000322, 2009.
P. A. Gibney, Lu, C., Caudy, A. A., Hess, D. C., and Botstein, D.,
“Yeast metabolic and signaling genes are required for heat-shock survival and have little overlap with the heat-induced genes.”,
Proc Natl Acad Sci U S A, vol. 110, no. 46, pp. E4393-402, 2013.
Y. - F. Xu, Létisse, F., Absalan, F., Lu, W., Kuznetsova, E., Brown, G., Caudy, A. A., Yakunin, A. F., Broach, J. R., and Rabinowitz, J. D.,
“Nucleotide degradation and ribose salvage in yeast.”,
Mol Syst Biol, vol. 9, p. 665, 2013.
Sequence Analysis, DNA
J. S. Bloom, Khan, Z., Kruglyak, L., Singh, M., and Caudy, A. A.,
“Measuring differential gene expression by short read sequencing: quantitative comparison to 2-channel gene expression microarrays.”,
BMC Genomics, vol. 10, p. 221, 2009.
Sequence Alignment
J. S. Bloom, Khan, Z., Kruglyak, L., Singh, M., and Caudy, A. A.,
“Measuring differential gene expression by short read sequencing: quantitative comparison to 2-channel gene expression microarrays.”,
BMC Genomics, vol. 10, p. 221, 2009.
Sensitivity and Specificity
Z. Khan, Amini, S., Bloom, J. S., Ruse, C., Caudy, A. A., Kruglyak, L., Singh, M., Perlman, D. H., and Tavazoie, S.,
“Accurate proteome-wide protein quantification from high-resolution 15N mass spectra.”,
Genome Biol, vol. 12, no. 12, p. R122, 2011.
Saccharomyces cerevisiae Proteins
Z. Khan, Bloom, J. S., Amini, S., Singh, M., Perlman, D. H., Caudy, A. A., and Kruglyak, L.,
“Quantitative measurement of allele-specific protein expression in a diploid yeast hybrid by LC-MS.”,
Mol Syst Biol, vol. 8, p. 602, 2012.
M. A. Hibbs, Myers, C. L., Huttenhower, C., Hess, D. C., Li, K., Caudy, A. A., and Troyanskaya, O. G.,
“Directing experimental biology: a case study in mitochondrial biogenesis.”,
PLoS Comput Biol, vol. 5, no. 3, p. e1000322, 2009.
M. Costanzo, VanderSluis, B., Koch, E. N., Baryshnikova, A., Pons, C., Tan, G., Wang, W., Usaj, M., Hanchard, J., Lee, S. D., Pelechano, V., Styles, E. B., Billmann, M., van Leeuwen, J., van Dyk, N., Lin, Z. - Y., Kuzmin, E., Nelson, J., Piotrowski, J. S., Srikumar, T., Bahr, S., Chen, Y., Deshpande, R., Kurat, C. F., Li, S. C., Li, Z., Usaj, M. Mattiazzi, Okada, H., Pascoe, N., San Luis, B. - J., Sharifpoor, S., Shuteriqi, E., Simpkins, S. W., Snider, J., Suresh, H. Garadi, Tan, Y., Zhu, H., Malod-Dognin, N., Janjic, V., Przulj, N., Troyanskaya, O. G., Stagljar, I., Xia, T., Ohya, Y., Gingras, A. - C., Raught, B., Boutros, M., Steinmetz, L. M., Moore, C. L., Rosebrock, A. P., Caudy, A. A., Myers, C. L., Andrews, B., and Boone, C.,
“A global genetic interaction network maps a wiring diagram of cellular function.”,
Science, vol. 353, no. 6306, 2016.
Y. Guan, Myers, C. L., Hess, D. C., Barutcuoglu, Z., Caudy, A. A., and Troyanskaya, O. G.,
“Predicting gene function in a hierarchical context with an ensemble of classifiers.”,
Genome Biol, vol. 9 Suppl 1, p. S3, 2008.
E. M. Airoldi, Huttenhower, C., Gresham, D., Lu, C., Caudy, A. A., Dunham, M. J., Broach, J. R., Botstein, D., and Troyanskaya, O. G.,
“Predicting cellular growth from gene expression signatures.”,
PLoS Comput Biol, vol. 5, no. 1, p. e1000257, 2009.
Y. - F. Xu, Létisse, F., Absalan, F., Lu, W., Kuznetsova, E., Brown, G., Caudy, A. A., Yakunin, A. F., Broach, J. R., and Rabinowitz, J. D.,
“Nucleotide degradation and ribose salvage in yeast.”,
Mol Syst Biol, vol. 9, p. 665, 2013.
Saccharomyces cerevisiae
M. A. Hibbs, Myers, C. L., Huttenhower, C., Hess, D. C., Li, K., Caudy, A. A., and Troyanskaya, O. G.,
“Directing experimental biology: a case study in mitochondrial biogenesis.”,
PLoS Comput Biol, vol. 5, no. 3, p. e1000322, 2009.
Y. Guan, Myers, C. L., Hess, D. C., Barutcuoglu, Z., Caudy, A. A., and Troyanskaya, O. G.,
“Predicting gene function in a hierarchical context with an ensemble of classifiers.”,
Genome Biol, vol. 9 Suppl 1, p. S3, 2008.
M. Costanzo, VanderSluis, B., Koch, E. N., Baryshnikova, A., Pons, C., Tan, G., Wang, W., Usaj, M., Hanchard, J., Lee, S. D., Pelechano, V., Styles, E. B., Billmann, M., van Leeuwen, J., van Dyk, N., Lin, Z. - Y., Kuzmin, E., Nelson, J., Piotrowski, J. S., Srikumar, T., Bahr, S., Chen, Y., Deshpande, R., Kurat, C. F., Li, S. C., Li, Z., Usaj, M. Mattiazzi, Okada, H., Pascoe, N., San Luis, B. - J., Sharifpoor, S., Shuteriqi, E., Simpkins, S. W., Snider, J., Suresh, H. Garadi, Tan, Y., Zhu, H., Malod-Dognin, N., Janjic, V., Przulj, N., Troyanskaya, O. G., Stagljar, I., Xia, T., Ohya, Y., Gingras, A. - C., Raught, B., Boutros, M., Steinmetz, L. M., Moore, C. L., Rosebrock, A. P., Caudy, A. A., Myers, C. L., Andrews, B., and Boone, C.,
“A global genetic interaction network maps a wiring diagram of cellular function.”,
Science, vol. 353, no. 6306, 2016.
D. C. Hess, Myers, C. L., Huttenhower, C., Hibbs, M. A., Hayes, A. P., Paw, J., Clore, J. J., Mendoza, R. M., San Luis, B., Nislow, C., Giaever, G., Costanzo, M., Troyanskaya, O. G., and Caudy, A. A.,
“Computationally driven, quantitative experiments discover genes required for mitochondrial biogenesis.”,
PLoS Genet, vol. 5, no. 3, p. e1000407, 2009.
W. Lu, Clasquin, M. F., Melamud, E., Amador-Noguez, D., Caudy, A. A., and Rabinowitz, J. D.,
“Metabolomic analysis via reversed-phase ion-pairing liquid chromatography coupled to a stand alone orbitrap mass spectrometer.”,
Anal Chem, vol. 82, no. 8, pp. 3212-21, 2010.
P. A. Gibney, Lu, C., Caudy, A. A., Hess, D. C., and Botstein, D.,
“Yeast metabolic and signaling genes are required for heat-shock survival and have little overlap with the heat-induced genes.”,
Proc Natl Acad Sci U S A, vol. 110, no. 46, pp. E4393-402, 2013.
E. M. Airoldi, Huttenhower, C., Gresham, D., Lu, C., Caudy, A. A., Dunham, M. J., Broach, J. R., Botstein, D., and Troyanskaya, O. G.,
“Predicting cellular growth from gene expression signatures.”,
PLoS Comput Biol, vol. 5, no. 1, p. e1000257, 2009.
M. F. Clasquin, Melamud, E., Singer, A., Gooding, J. R., Xu, X., Dong, A., Cui, H., Campagna, S. R., Savchenko, A., Yakunin, A. F., Rabinowitz, J. D., and Caudy, A. A.,
“Riboneogenesis in yeast.”,
Cell, vol. 145, no. 6, pp. 969-80, 2011.
J. S. Bloom, Khan, Z., Kruglyak, L., Singh, M., and Caudy, A. A.,
“Measuring differential gene expression by short read sequencing: quantitative comparison to 2-channel gene expression microarrays.”,
BMC Genomics, vol. 10, p. 221, 2009.
Y. Guan, Dunham, M. J., Troyanskaya, O. G., and Caudy, A. A.,
“Comparative gene expression between two yeast species.”,
BMC Genomics, vol. 14, p. 33, 2013.
Y. - F. Xu, Létisse, F., Absalan, F., Lu, W., Kuznetsova, E., Brown, G., Caudy, A. A., Yakunin, A. F., Broach, J. R., and Rabinowitz, J. D.,
“Nucleotide degradation and ribose salvage in yeast.”,
Mol Syst Biol, vol. 9, p. 665, 2013.
Z. Khan, Bloom, J. S., Amini, S., Singh, M., Perlman, D. H., Caudy, A. A., and Kruglyak, L.,
“Quantitative measurement of allele-specific protein expression in a diploid yeast hybrid by LC-MS.”,
Mol Syst Biol, vol. 8, p. 602, 2012.
C. Huttenhower, Hibbs, M. A., Myers, C. L., Caudy, A. A., Hess, D. C., and Troyanskaya, O. G.,
“The impact of incomplete knowledge on evaluation: an experimental benchmark for protein function prediction.”,
Bioinformatics, vol. 25, no. 18, pp. 2404-10, 2009.
Saccharomyces
Z. Khan, Bloom, J. S., Amini, S., Singh, M., Perlman, D. H., Caudy, A. A., and Kruglyak, L.,
“Quantitative measurement of allele-specific protein expression in a diploid yeast hybrid by LC-MS.”,
Mol Syst Biol, vol. 8, p. 602, 2012.
A. A. Caudy, Guan, Y., Jia, Y., Hansen, C., DeSevo, C., Hayes, A. P., Agee, J., Alvarez-Dominguez, J. R., Arellano, H., Barrett, D., Bauerle, C., Bisaria, N., Bradley, P. H., J Breunig, S., Bush, E., Cappel, D., Capra, E., Chen, W., Clore, J., Combs, P. A., Doucette, C., Demuren, O., Fellowes, P., Freeman, S., Frenkel, E., Gadala-Maria, D., Gawande, R., Glass, D., Grossberg, S., Gupta, A., Hammonds-Odie, L., Hoisos, A., Hsi, J., Hsu, Y. - H. Huang, Inukai, S., Karczewski, K. J., Ke, X., Kojima, M., Leachman, S., Lieber, D., Liebowitz, A., Liu, J., Liu, Y., Martin, T., Mena, J., Mendoza, R., Myhrvold, C., Millian, C., Pfau, S., Raj, S., Rich, M., Rokicki, J., Rounds, W., Salazar, M., Salesi, M., Sharma, R., Silverman, S., Singer, C., Sinha, S., Staller, M., Stern, P., Tang, H., Weeks, S., Weidmann, M., Wolf, A., Young, C., Yuan, J., Crutchfield, C., McClean, M., Murphy, C. T., Llinás, M., Botstein, D., Troyanskaya, O. G., and Dunham, M. J.,
“A new system for comparative functional genomics of Saccharomyces yeasts.”,
Genetics, vol. 195, no. 1, pp. 275-87, 2013.
Ribosemonophosphates
M. F. Clasquin, Melamud, E., Singer, A., Gooding, J. R., Xu, X., Dong, A., Cui, H., Campagna, S. R., Savchenko, A., Yakunin, A. F., Rabinowitz, J. D., and Caudy, A. A.,
“Riboneogenesis in yeast.”,
Cell, vol. 145, no. 6, pp. 969-80, 2011.
Ribose
Y. - F. Xu, Létisse, F., Absalan, F., Lu, W., Kuznetsova, E., Brown, G., Caudy, A. A., Yakunin, A. F., Broach, J. R., and Rabinowitz, J. D.,
“Nucleotide degradation and ribose salvage in yeast.”,
Mol Syst Biol, vol. 9, p. 665, 2013.
Research Design
M. A. Hibbs, Myers, C. L., Huttenhower, C., Hess, D. C., Li, K., Caudy, A. A., and Troyanskaya, O. G.,
“Directing experimental biology: a case study in mitochondrial biogenesis.”,
PLoS Comput Biol, vol. 5, no. 3, p. e1000322, 2009.
Regression Analysis
Z. Khan, Bloom, J. S., Amini, S., Singh, M., Perlman, D. H., Caudy, A. A., and Kruglyak, L.,
“Quantitative measurement of allele-specific protein expression in a diploid yeast hybrid by LC-MS.”,
Mol Syst Biol, vol. 8, p. 602, 2012.
Pyroglutamate Hydrolase
W. Lu, Clasquin, M. F., Melamud, E., Amador-Noguez, D., Caudy, A. A., and Rabinowitz, J. D.,
“Metabolomic analysis via reversed-phase ion-pairing liquid chromatography coupled to a stand alone orbitrap mass spectrometer.”,
Anal Chem, vol. 82, no. 8, pp. 3212-21, 2010.
Purine-Nucleoside Phosphorylase
Y. - F. Xu, Létisse, F., Absalan, F., Lu, W., Kuznetsova, E., Brown, G., Caudy, A. A., Yakunin, A. F., Broach, J. R., and Rabinowitz, J. D.,
“Nucleotide degradation and ribose salvage in yeast.”,
Mol Syst Biol, vol. 9, p. 665, 2013.
Proteomics
Z. Khan, Amini, S., Bloom, J. S., Ruse, C., Caudy, A. A., Kruglyak, L., Singh, M., Perlman, D. H., and Tavazoie, S.,
“Accurate proteome-wide protein quantification from high-resolution 15N mass spectra.”,
Genome Biol, vol. 12, no. 12, p. R122, 2011.
D. C. Hess, Myers, C. L., Huttenhower, C., Hibbs, M. A., Hayes, A. P., Paw, J., Clore, J. J., Mendoza, R. M., San Luis, B., Nislow, C., Giaever, G., Costanzo, M., Troyanskaya, O. G., and Caudy, A. A.,
“Computationally driven, quantitative experiments discover genes required for mitochondrial biogenesis.”,
PLoS Genet, vol. 5, no. 3, p. e1000407, 2009.
Z. Khan, Bloom, J. S., Amini, S., Singh, M., Perlman, D. H., Caudy, A. A., and Kruglyak, L.,
“Quantitative measurement of allele-specific protein expression in a diploid yeast hybrid by LC-MS.”,
Mol Syst Biol, vol. 8, p. 602, 2012.
Proteome
Z. Khan, Amini, S., Bloom, J. S., Ruse, C., Caudy, A. A., Kruglyak, L., Singh, M., Perlman, D. H., and Tavazoie, S.,
“Accurate proteome-wide protein quantification from high-resolution 15N mass spectra.”,
Genome Biol, vol. 12, no. 12, p. R122, 2011.
E. M. Airoldi, Huttenhower, C., Gresham, D., Lu, C., Caudy, A. A., Dunham, M. J., Broach, J. R., Botstein, D., and Troyanskaya, O. G.,
“Predicting cellular growth from gene expression signatures.”,
PLoS Comput Biol, vol. 5, no. 1, p. e1000257, 2009.
Proteins
Y. Guan, Myers, C. L., Hess, D. C., Barutcuoglu, Z., Caudy, A. A., and Troyanskaya, O. G.,
“Predicting gene function in a hierarchical context with an ensemble of classifiers.”,
Genome Biol, vol. 9 Suppl 1, p. S3, 2008.
D. C. Hess, Myers, C. L., Huttenhower, C., Hibbs, M. A., Hayes, A. P., Paw, J., Clore, J. J., Mendoza, R. M., San Luis, B., Nislow, C., Giaever, G., Costanzo, M., Troyanskaya, O. G., and Caudy, A. A.,
“Computationally driven, quantitative experiments discover genes required for mitochondrial biogenesis.”,
PLoS Genet, vol. 5, no. 3, p. e1000407, 2009.
C. Huttenhower, Hibbs, M. A., Myers, C. L., Caudy, A. A., Hess, D. C., and Troyanskaya, O. G.,
“The impact of incomplete knowledge on evaluation: an experimental benchmark for protein function prediction.”,
Bioinformatics, vol. 25, no. 18, pp. 2404-10, 2009.
Protein-Serine-Threonine Kinases
Y. - F. Xu, Létisse, F., Absalan, F., Lu, W., Kuznetsova, E., Brown, G., Caudy, A. A., Yakunin, A. F., Broach, J. R., and Rabinowitz, J. D.,
“Nucleotide degradation and ribose salvage in yeast.”,
Mol Syst Biol, vol. 9, p. 665, 2013.
Phosphoric Monoester Hydrolases
M. F. Clasquin, Melamud, E., Singer, A., Gooding, J. R., Xu, X., Dong, A., Cui, H., Campagna, S. R., Savchenko, A., Yakunin, A. F., Rabinowitz, J. D., and Caudy, A. A.,
“Riboneogenesis in yeast.”,
Cell, vol. 145, no. 6, pp. 969-80, 2011.
Pentose Phosphate Pathway
M. F. Clasquin, Melamud, E., Singer, A., Gooding, J. R., Xu, X., Dong, A., Cui, H., Campagna, S. R., Savchenko, A., Yakunin, A. F., Rabinowitz, J. D., and Caudy, A. A.,
“Riboneogenesis in yeast.”,
Cell, vol. 145, no. 6, pp. 969-80, 2011.
Y. - F. Xu, Létisse, F., Absalan, F., Lu, W., Kuznetsova, E., Brown, G., Caudy, A. A., Yakunin, A. F., Broach, J. R., and Rabinowitz, J. D.,
“Nucleotide degradation and ribose salvage in yeast.”,
Mol Syst Biol, vol. 9, p. 665, 2013.
Oxidative Stress
A. A. Caudy, Guan, Y., Jia, Y., Hansen, C., DeSevo, C., Hayes, A. P., Agee, J., Alvarez-Dominguez, J. R., Arellano, H., Barrett, D., Bauerle, C., Bisaria, N., Bradley, P. H., J Breunig, S., Bush, E., Cappel, D., Capra, E., Chen, W., Clore, J., Combs, P. A., Doucette, C., Demuren, O., Fellowes, P., Freeman, S., Frenkel, E., Gadala-Maria, D., Gawande, R., Glass, D., Grossberg, S., Gupta, A., Hammonds-Odie, L., Hoisos, A., Hsi, J., Hsu, Y. - H. Huang, Inukai, S., Karczewski, K. J., Ke, X., Kojima, M., Leachman, S., Lieber, D., Liebowitz, A., Liu, J., Liu, Y., Martin, T., Mena, J., Mendoza, R., Myhrvold, C., Millian, C., Pfau, S., Raj, S., Rich, M., Rokicki, J., Rounds, W., Salazar, M., Salesi, M., Sharma, R., Silverman, S., Singer, C., Sinha, S., Staller, M., Stern, P., Tang, H., Weeks, S., Weidmann, M., Wolf, A., Young, C., Yuan, J., Crutchfield, C., McClean, M., Murphy, C. T., Llinás, M., Botstein, D., Troyanskaya, O. G., and Dunham, M. J.,
“A new system for comparative functional genomics of Saccharomyces yeasts.”,
Genetics, vol. 195, no. 1, pp. 275-87, 2013.
Oligonucleotide Array Sequence Analysis
J. S. Bloom, Khan, Z., Kruglyak, L., Singh, M., and Caudy, A. A.,
“Measuring differential gene expression by short read sequencing: quantitative comparison to 2-channel gene expression microarrays.”,
BMC Genomics, vol. 10, p. 221, 2009.
Nucleotides
Y. - F. Xu, Létisse, F., Absalan, F., Lu, W., Kuznetsova, E., Brown, G., Caudy, A. A., Yakunin, A. F., Broach, J. R., and Rabinowitz, J. D.,
“Nucleotide degradation and ribose salvage in yeast.”,
Mol Syst Biol, vol. 9, p. 665, 2013.
Nitrogen Isotopes
Z. Khan, Amini, S., Bloom, J. S., Ruse, C., Caudy, A. A., Kruglyak, L., Singh, M., Perlman, D. H., and Tavazoie, S.,
“Accurate proteome-wide protein quantification from high-resolution 15N mass spectra.”,
Genome Biol, vol. 12, no. 12, p. R122, 2011.
NADP
Y. - F. Xu, Létisse, F., Absalan, F., Lu, W., Kuznetsova, E., Brown, G., Caudy, A. A., Yakunin, A. F., Broach, J. R., and Rabinowitz, J. D.,
“Nucleotide degradation and ribose salvage in yeast.”,
Mol Syst Biol, vol. 9, p. 665, 2013.
N-Glycosyl Hydrolases
Y. - F. Xu, Létisse, F., Absalan, F., Lu, W., Kuznetsova, E., Brown, G., Caudy, A. A., Yakunin, A. F., Broach, J. R., and Rabinowitz, J. D.,
“Nucleotide degradation and ribose salvage in yeast.”,
Mol Syst Biol, vol. 9, p. 665, 2013.
Mutation
D. C. Hess, Myers, C. L., Huttenhower, C., Hibbs, M. A., Hayes, A. P., Paw, J., Clore, J. J., Mendoza, R. M., San Luis, B., Nislow, C., Giaever, G., Costanzo, M., Troyanskaya, O. G., and Caudy, A. A.,
“Computationally driven, quantitative experiments discover genes required for mitochondrial biogenesis.”,
PLoS Genet, vol. 5, no. 3, p. e1000407, 2009.
Mutant Proteins
D. C. Hess, Myers, C. L., Huttenhower, C., Hibbs, M. A., Hayes, A. P., Paw, J., Clore, J. J., Mendoza, R. M., San Luis, B., Nislow, C., Giaever, G., Costanzo, M., Troyanskaya, O. G., and Caudy, A. A.,
“Computationally driven, quantitative experiments discover genes required for mitochondrial biogenesis.”,
PLoS Genet, vol. 5, no. 3, p. e1000407, 2009.
Molecular Sequence Data
Z. Khan, Amini, S., Bloom, J. S., Ruse, C., Caudy, A. A., Kruglyak, L., Singh, M., Perlman, D. H., and Tavazoie, S.,
“Accurate proteome-wide protein quantification from high-resolution 15N mass spectra.”,
Genome Biol, vol. 12, no. 12, p. R122, 2011.
Molecular Sequence Annotation
A. A. Caudy, Guan, Y., Jia, Y., Hansen, C., DeSevo, C., Hayes, A. P., Agee, J., Alvarez-Dominguez, J. R., Arellano, H., Barrett, D., Bauerle, C., Bisaria, N., Bradley, P. H., J Breunig, S., Bush, E., Cappel, D., Capra, E., Chen, W., Clore, J., Combs, P. A., Doucette, C., Demuren, O., Fellowes, P., Freeman, S., Frenkel, E., Gadala-Maria, D., Gawande, R., Glass, D., Grossberg, S., Gupta, A., Hammonds-Odie, L., Hoisos, A., Hsi, J., Hsu, Y. - H. Huang, Inukai, S., Karczewski, K. J., Ke, X., Kojima, M., Leachman, S., Lieber, D., Liebowitz, A., Liu, J., Liu, Y., Martin, T., Mena, J., Mendoza, R., Myhrvold, C., Millian, C., Pfau, S., Raj, S., Rich, M., Rokicki, J., Rounds, W., Salazar, M., Salesi, M., Sharma, R., Silverman, S., Singer, C., Sinha, S., Staller, M., Stern, P., Tang, H., Weeks, S., Weidmann, M., Wolf, A., Young, C., Yuan, J., Crutchfield, C., McClean, M., Murphy, C. T., Llinás, M., Botstein, D., Troyanskaya, O. G., and Dunham, M. J.,
“A new system for comparative functional genomics of Saccharomyces yeasts.”,
Genetics, vol. 195, no. 1, pp. 275-87, 2013.
P. A. Gibney, Lu, C., Caudy, A. A., Hess, D. C., and Botstein, D.,
“Yeast metabolic and signaling genes are required for heat-shock survival and have little overlap with the heat-induced genes.”,
Proc Natl Acad Sci U S A, vol. 110, no. 46, pp. E4393-402, 2013.
Models, Molecular
M. F. Clasquin, Melamud, E., Singer, A., Gooding, J. R., Xu, X., Dong, A., Cui, H., Campagna, S. R., Savchenko, A., Yakunin, A. F., Rabinowitz, J. D., and Caudy, A. A.,
“Riboneogenesis in yeast.”,
Cell, vol. 145, no. 6, pp. 969-80, 2011.
Models, Biological
M. A. Hibbs, Myers, C. L., Huttenhower, C., Hess, D. C., Li, K., Caudy, A. A., and Troyanskaya, O. G.,
“Directing experimental biology: a case study in mitochondrial biogenesis.”,
PLoS Comput Biol, vol. 5, no. 3, p. e1000322, 2009.
E. M. Airoldi, Huttenhower, C., Gresham, D., Lu, C., Caudy, A. A., Dunham, M. J., Broach, J. R., Botstein, D., and Troyanskaya, O. G.,
“Predicting cellular growth from gene expression signatures.”,
PLoS Comput Biol, vol. 5, no. 1, p. e1000257, 2009.
Mitochondrial Proteins
M. A. Hibbs, Myers, C. L., Huttenhower, C., Hess, D. C., Li, K., Caudy, A. A., and Troyanskaya, O. G.,
“Directing experimental biology: a case study in mitochondrial biogenesis.”,
PLoS Comput Biol, vol. 5, no. 3, p. e1000322, 2009.
Y. Guan, Myers, C. L., Hess, D. C., Barutcuoglu, Z., Caudy, A. A., and Troyanskaya, O. G.,
“Predicting gene function in a hierarchical context with an ensemble of classifiers.”,
Genome Biol, vol. 9 Suppl 1, p. S3, 2008.
D. C. Hess, Myers, C. L., Huttenhower, C., Hibbs, M. A., Hayes, A. P., Paw, J., Clore, J. J., Mendoza, R. M., San Luis, B., Nislow, C., Giaever, G., Costanzo, M., Troyanskaya, O. G., and Caudy, A. A.,
“Computationally driven, quantitative experiments discover genes required for mitochondrial biogenesis.”,
PLoS Genet, vol. 5, no. 3, p. e1000407, 2009.
Mitochondria
C. Huttenhower, Hibbs, M. A., Myers, C. L., Caudy, A. A., Hess, D. C., and Troyanskaya, O. G.,
“The impact of incomplete knowledge on evaluation: an experimental benchmark for protein function prediction.”,
Bioinformatics, vol. 25, no. 18, pp. 2404-10, 2009.
M. A. Hibbs, Myers, C. L., Huttenhower, C., Hess, D. C., Li, K., Caudy, A. A., and Troyanskaya, O. G.,
“Directing experimental biology: a case study in mitochondrial biogenesis.”,
PLoS Comput Biol, vol. 5, no. 3, p. e1000322, 2009.
D. C. Hess, Myers, C. L., Huttenhower, C., Hibbs, M. A., Hayes, A. P., Paw, J., Clore, J. J., Mendoza, R. M., San Luis, B., Nislow, C., Giaever, G., Costanzo, M., Troyanskaya, O. G., and Caudy, A. A.,
“Computationally driven, quantitative experiments discover genes required for mitochondrial biogenesis.”,
PLoS Genet, vol. 5, no. 3, p. e1000407, 2009.
Mice
Y. Guan, Myers, C. L., Hess, D. C., Barutcuoglu, Z., Caudy, A. A., and Troyanskaya, O. G.,
“Predicting gene function in a hierarchical context with an ensemble of classifiers.”,
Genome Biol, vol. 9 Suppl 1, p. S3, 2008.
Metabolomics
W. Lu, Clasquin, M. F., Melamud, E., Amador-Noguez, D., Caudy, A. A., and Rabinowitz, J. D.,
“Metabolomic analysis via reversed-phase ion-pairing liquid chromatography coupled to a stand alone orbitrap mass spectrometer.”,
Anal Chem, vol. 82, no. 8, pp. 3212-21, 2010.
Metabolome
W. Lu, Clasquin, M. F., Melamud, E., Amador-Noguez, D., Caudy, A. A., and Rabinowitz, J. D.,
“Metabolomic analysis via reversed-phase ion-pairing liquid chromatography coupled to a stand alone orbitrap mass spectrometer.”,
Anal Chem, vol. 82, no. 8, pp. 3212-21, 2010.
Metabolic Networks and Pathways
P. A. Gibney, Lu, C., Caudy, A. A., Hess, D. C., and Botstein, D.,
“Yeast metabolic and signaling genes are required for heat-shock survival and have little overlap with the heat-induced genes.”,
Proc Natl Acad Sci U S A, vol. 110, no. 46, pp. E4393-402, 2013.
Mass Spectrometry
Z. Khan, Bloom, J. S., Amini, S., Singh, M., Perlman, D. H., Caudy, A. A., and Kruglyak, L.,
“Quantitative measurement of allele-specific protein expression in a diploid yeast hybrid by LC-MS.”,
Mol Syst Biol, vol. 8, p. 602, 2012.
Z. Khan, Amini, S., Bloom, J. S., Ruse, C., Caudy, A. A., Kruglyak, L., Singh, M., Perlman, D. H., and Tavazoie, S.,
“Accurate proteome-wide protein quantification from high-resolution 15N mass spectra.”,
Genome Biol, vol. 12, no. 12, p. R122, 2011.
Kinetics
W. Lu, Clasquin, M. F., Melamud, E., Amador-Noguez, D., Caudy, A. A., and Rabinowitz, J. D.,
“Metabolomic analysis via reversed-phase ion-pairing liquid chromatography coupled to a stand alone orbitrap mass spectrometer.”,
Anal Chem, vol. 82, no. 8, pp. 3212-21, 2010.
Isotope Labeling
Z. Khan, Amini, S., Bloom, J. S., Ruse, C., Caudy, A. A., Kruglyak, L., Singh, M., Perlman, D. H., and Tavazoie, S.,
“Accurate proteome-wide protein quantification from high-resolution 15N mass spectra.”,
Genome Biol, vol. 12, no. 12, p. R122, 2011.
Humans
Z. Khan, Bloom, J. S., Amini, S., Singh, M., Perlman, D. H., Caudy, A. A., and Kruglyak, L.,
“Quantitative measurement of allele-specific protein expression in a diploid yeast hybrid by LC-MS.”,
Mol Syst Biol, vol. 8, p. 602, 2012.
High-Throughput Nucleotide Sequencing
P. A. Gibney, Lu, C., Caudy, A. A., Hess, D. C., and Botstein, D.,
“Yeast metabolic and signaling genes are required for heat-shock survival and have little overlap with the heat-induced genes.”,
Proc Natl Acad Sci U S A, vol. 110, no. 46, pp. E4393-402, 2013.
Heat-Shock Response
P. A. Gibney, Lu, C., Caudy, A. A., Hess, D. C., and Botstein, D.,
“Yeast metabolic and signaling genes are required for heat-shock survival and have little overlap with the heat-induced genes.”,
Proc Natl Acad Sci U S A, vol. 110, no. 46, pp. E4393-402, 2013.
Glyceraldehyde 3-Phosphate
Y. - F. Xu, Létisse, F., Absalan, F., Lu, W., Kuznetsova, E., Brown, G., Caudy, A. A., Yakunin, A. F., Broach, J. R., and Rabinowitz, J. D.,
“Nucleotide degradation and ribose salvage in yeast.”,
Mol Syst Biol, vol. 9, p. 665, 2013.
Genome, Fungal
A. A. Caudy, Guan, Y., Jia, Y., Hansen, C., DeSevo, C., Hayes, A. P., Agee, J., Alvarez-Dominguez, J. R., Arellano, H., Barrett, D., Bauerle, C., Bisaria, N., Bradley, P. H., J Breunig, S., Bush, E., Cappel, D., Capra, E., Chen, W., Clore, J., Combs, P. A., Doucette, C., Demuren, O., Fellowes, P., Freeman, S., Frenkel, E., Gadala-Maria, D., Gawande, R., Glass, D., Grossberg, S., Gupta, A., Hammonds-Odie, L., Hoisos, A., Hsi, J., Hsu, Y. - H. Huang, Inukai, S., Karczewski, K. J., Ke, X., Kojima, M., Leachman, S., Lieber, D., Liebowitz, A., Liu, J., Liu, Y., Martin, T., Mena, J., Mendoza, R., Myhrvold, C., Millian, C., Pfau, S., Raj, S., Rich, M., Rokicki, J., Rounds, W., Salazar, M., Salesi, M., Sharma, R., Silverman, S., Singer, C., Sinha, S., Staller, M., Stern, P., Tang, H., Weeks, S., Weidmann, M., Wolf, A., Young, C., Yuan, J., Crutchfield, C., McClean, M., Murphy, C. T., Llinás, M., Botstein, D., Troyanskaya, O. G., and Dunham, M. J.,
“A new system for comparative functional genomics of Saccharomyces yeasts.”,
Genetics, vol. 195, no. 1, pp. 275-87, 2013.
Genetic Variation
Y. Guan, Dunham, M. J., Troyanskaya, O. G., and Caudy, A. A.,
“Comparative gene expression between two yeast species.”,
BMC Genomics, vol. 14, p. 33, 2013.
Genetic Pleiotropy
M. Costanzo, VanderSluis, B., Koch, E. N., Baryshnikova, A., Pons, C., Tan, G., Wang, W., Usaj, M., Hanchard, J., Lee, S. D., Pelechano, V., Styles, E. B., Billmann, M., van Leeuwen, J., van Dyk, N., Lin, Z. - Y., Kuzmin, E., Nelson, J., Piotrowski, J. S., Srikumar, T., Bahr, S., Chen, Y., Deshpande, R., Kurat, C. F., Li, S. C., Li, Z., Usaj, M. Mattiazzi, Okada, H., Pascoe, N., San Luis, B. - J., Sharifpoor, S., Shuteriqi, E., Simpkins, S. W., Snider, J., Suresh, H. Garadi, Tan, Y., Zhu, H., Malod-Dognin, N., Janjic, V., Przulj, N., Troyanskaya, O. G., Stagljar, I., Xia, T., Ohya, Y., Gingras, A. - C., Raught, B., Boutros, M., Steinmetz, L. M., Moore, C. L., Rosebrock, A. P., Caudy, A. A., Myers, C. L., Andrews, B., and Boone, C.,
“A global genetic interaction network maps a wiring diagram of cellular function.”,
Science, vol. 353, no. 6306, 2016.
Genetic Markers
P. A. Gibney, Lu, C., Caudy, A. A., Hess, D. C., and Botstein, D.,
“Yeast metabolic and signaling genes are required for heat-shock survival and have little overlap with the heat-induced genes.”,
Proc Natl Acad Sci U S A, vol. 110, no. 46, pp. E4393-402, 2013.
Genes, Mitochondrial
D. C. Hess, Myers, C. L., Huttenhower, C., Hibbs, M. A., Hayes, A. P., Paw, J., Clore, J. J., Mendoza, R. M., San Luis, B., Nislow, C., Giaever, G., Costanzo, M., Troyanskaya, O. G., and Caudy, A. A.,
“Computationally driven, quantitative experiments discover genes required for mitochondrial biogenesis.”,
PLoS Genet, vol. 5, no. 3, p. e1000407, 2009.
Genes, Fungal
M. Costanzo, VanderSluis, B., Koch, E. N., Baryshnikova, A., Pons, C., Tan, G., Wang, W., Usaj, M., Hanchard, J., Lee, S. D., Pelechano, V., Styles, E. B., Billmann, M., van Leeuwen, J., van Dyk, N., Lin, Z. - Y., Kuzmin, E., Nelson, J., Piotrowski, J. S., Srikumar, T., Bahr, S., Chen, Y., Deshpande, R., Kurat, C. F., Li, S. C., Li, Z., Usaj, M. Mattiazzi, Okada, H., Pascoe, N., San Luis, B. - J., Sharifpoor, S., Shuteriqi, E., Simpkins, S. W., Snider, J., Suresh, H. Garadi, Tan, Y., Zhu, H., Malod-Dognin, N., Janjic, V., Przulj, N., Troyanskaya, O. G., Stagljar, I., Xia, T., Ohya, Y., Gingras, A. - C., Raught, B., Boutros, M., Steinmetz, L. M., Moore, C. L., Rosebrock, A. P., Caudy, A. A., Myers, C. L., Andrews, B., and Boone, C.,
“A global genetic interaction network maps a wiring diagram of cellular function.”,
Science, vol. 353, no. 6306, 2016.
Genes, Essential
M. Costanzo, VanderSluis, B., Koch, E. N., Baryshnikova, A., Pons, C., Tan, G., Wang, W., Usaj, M., Hanchard, J., Lee, S. D., Pelechano, V., Styles, E. B., Billmann, M., van Leeuwen, J., van Dyk, N., Lin, Z. - Y., Kuzmin, E., Nelson, J., Piotrowski, J. S., Srikumar, T., Bahr, S., Chen, Y., Deshpande, R., Kurat, C. F., Li, S. C., Li, Z., Usaj, M. Mattiazzi, Okada, H., Pascoe, N., San Luis, B. - J., Sharifpoor, S., Shuteriqi, E., Simpkins, S. W., Snider, J., Suresh, H. Garadi, Tan, Y., Zhu, H., Malod-Dognin, N., Janjic, V., Przulj, N., Troyanskaya, O. G., Stagljar, I., Xia, T., Ohya, Y., Gingras, A. - C., Raught, B., Boutros, M., Steinmetz, L. M., Moore, C. L., Rosebrock, A. P., Caudy, A. A., Myers, C. L., Andrews, B., and Boone, C.,
“A global genetic interaction network maps a wiring diagram of cellular function.”,
Science, vol. 353, no. 6306, 2016.
Gene Regulatory Networks
M. Costanzo, VanderSluis, B., Koch, E. N., Baryshnikova, A., Pons, C., Tan, G., Wang, W., Usaj, M., Hanchard, J., Lee, S. D., Pelechano, V., Styles, E. B., Billmann, M., van Leeuwen, J., van Dyk, N., Lin, Z. - Y., Kuzmin, E., Nelson, J., Piotrowski, J. S., Srikumar, T., Bahr, S., Chen, Y., Deshpande, R., Kurat, C. F., Li, S. C., Li, Z., Usaj, M. Mattiazzi, Okada, H., Pascoe, N., San Luis, B. - J., Sharifpoor, S., Shuteriqi, E., Simpkins, S. W., Snider, J., Suresh, H. Garadi, Tan, Y., Zhu, H., Malod-Dognin, N., Janjic, V., Przulj, N., Troyanskaya, O. G., Stagljar, I., Xia, T., Ohya, Y., Gingras, A. - C., Raught, B., Boutros, M., Steinmetz, L. M., Moore, C. L., Rosebrock, A. P., Caudy, A. A., Myers, C. L., Andrews, B., and Boone, C.,
“A global genetic interaction network maps a wiring diagram of cellular function.”,
Science, vol. 353, no. 6306, 2016.
Gene Expression Regulation, Fungal
P. A. Gibney, Lu, C., Caudy, A. A., Hess, D. C., and Botstein, D.,
“Yeast metabolic and signaling genes are required for heat-shock survival and have little overlap with the heat-induced genes.”,
Proc Natl Acad Sci U S A, vol. 110, no. 46, pp. E4393-402, 2013.
Y. Guan, Dunham, M. J., Troyanskaya, O. G., and Caudy, A. A.,
“Comparative gene expression between two yeast species.”,
BMC Genomics, vol. 14, p. 33, 2013.
Y. - F. Xu, Létisse, F., Absalan, F., Lu, W., Kuznetsova, E., Brown, G., Caudy, A. A., Yakunin, A. F., Broach, J. R., and Rabinowitz, J. D.,
“Nucleotide degradation and ribose salvage in yeast.”,
Mol Syst Biol, vol. 9, p. 665, 2013.
Z. Khan, Bloom, J. S., Amini, S., Singh, M., Perlman, D. H., Caudy, A. A., and Kruglyak, L.,
“Quantitative measurement of allele-specific protein expression in a diploid yeast hybrid by LC-MS.”,
Mol Syst Biol, vol. 8, p. 602, 2012.
Gene Expression Profiling
A. A. Caudy, Guan, Y., Jia, Y., Hansen, C., DeSevo, C., Hayes, A. P., Agee, J., Alvarez-Dominguez, J. R., Arellano, H., Barrett, D., Bauerle, C., Bisaria, N., Bradley, P. H., J Breunig, S., Bush, E., Cappel, D., Capra, E., Chen, W., Clore, J., Combs, P. A., Doucette, C., Demuren, O., Fellowes, P., Freeman, S., Frenkel, E., Gadala-Maria, D., Gawande, R., Glass, D., Grossberg, S., Gupta, A., Hammonds-Odie, L., Hoisos, A., Hsi, J., Hsu, Y. - H. Huang, Inukai, S., Karczewski, K. J., Ke, X., Kojima, M., Leachman, S., Lieber, D., Liebowitz, A., Liu, J., Liu, Y., Martin, T., Mena, J., Mendoza, R., Myhrvold, C., Millian, C., Pfau, S., Raj, S., Rich, M., Rokicki, J., Rounds, W., Salazar, M., Salesi, M., Sharma, R., Silverman, S., Singer, C., Sinha, S., Staller, M., Stern, P., Tang, H., Weeks, S., Weidmann, M., Wolf, A., Young, C., Yuan, J., Crutchfield, C., McClean, M., Murphy, C. T., Llinás, M., Botstein, D., Troyanskaya, O. G., and Dunham, M. J.,
“A new system for comparative functional genomics of Saccharomyces yeasts.”,
Genetics, vol. 195, no. 1, pp. 275-87, 2013.
P. A. Gibney, Lu, C., Caudy, A. A., Hess, D. C., and Botstein, D.,
“Yeast metabolic and signaling genes are required for heat-shock survival and have little overlap with the heat-induced genes.”,
Proc Natl Acad Sci U S A, vol. 110, no. 46, pp. E4393-402, 2013.
E. M. Airoldi, Huttenhower, C., Gresham, D., Lu, C., Caudy, A. A., Dunham, M. J., Broach, J. R., Botstein, D., and Troyanskaya, O. G.,
“Predicting cellular growth from gene expression signatures.”,
PLoS Comput Biol, vol. 5, no. 1, p. e1000257, 2009.
J. S. Bloom, Khan, Z., Kruglyak, L., Singh, M., and Caudy, A. A.,
“Measuring differential gene expression by short read sequencing: quantitative comparison to 2-channel gene expression microarrays.”,
BMC Genomics, vol. 10, p. 221, 2009.
Y. Guan, Dunham, M. J., Troyanskaya, O. G., and Caudy, A. A.,
“Comparative gene expression between two yeast species.”,
BMC Genomics, vol. 14, p. 33, 2013.
Z. Khan, Bloom, J. S., Amini, S., Singh, M., Perlman, D. H., Caudy, A. A., and Kruglyak, L.,
“Quantitative measurement of allele-specific protein expression in a diploid yeast hybrid by LC-MS.”,
Mol Syst Biol, vol. 8, p. 602, 2012.
Gene Deletion
P. A. Gibney, Lu, C., Caudy, A. A., Hess, D. C., and Botstein, D.,
“Yeast metabolic and signaling genes are required for heat-shock survival and have little overlap with the heat-induced genes.”,
Proc Natl Acad Sci U S A, vol. 110, no. 46, pp. E4393-402, 2013.
M. F. Clasquin, Melamud, E., Singer, A., Gooding, J. R., Xu, X., Dong, A., Cui, H., Campagna, S. R., Savchenko, A., Yakunin, A. F., Rabinowitz, J. D., and Caudy, A. A.,
“Riboneogenesis in yeast.”,
Cell, vol. 145, no. 6, pp. 969-80, 2011.
Fungal Proteins
A. A. Caudy, Guan, Y., Jia, Y., Hansen, C., DeSevo, C., Hayes, A. P., Agee, J., Alvarez-Dominguez, J. R., Arellano, H., Barrett, D., Bauerle, C., Bisaria, N., Bradley, P. H., J Breunig, S., Bush, E., Cappel, D., Capra, E., Chen, W., Clore, J., Combs, P. A., Doucette, C., Demuren, O., Fellowes, P., Freeman, S., Frenkel, E., Gadala-Maria, D., Gawande, R., Glass, D., Grossberg, S., Gupta, A., Hammonds-Odie, L., Hoisos, A., Hsi, J., Hsu, Y. - H. Huang, Inukai, S., Karczewski, K. J., Ke, X., Kojima, M., Leachman, S., Lieber, D., Liebowitz, A., Liu, J., Liu, Y., Martin, T., Mena, J., Mendoza, R., Myhrvold, C., Millian, C., Pfau, S., Raj, S., Rich, M., Rokicki, J., Rounds, W., Salazar, M., Salesi, M., Sharma, R., Silverman, S., Singer, C., Sinha, S., Staller, M., Stern, P., Tang, H., Weeks, S., Weidmann, M., Wolf, A., Young, C., Yuan, J., Crutchfield, C., McClean, M., Murphy, C. T., Llinás, M., Botstein, D., Troyanskaya, O. G., and Dunham, M. J.,
“A new system for comparative functional genomics of Saccharomyces yeasts.”,
Genetics, vol. 195, no. 1, pp. 275-87, 2013.
Z. Khan, Bloom, J. S., Amini, S., Singh, M., Perlman, D. H., Caudy, A. A., and Kruglyak, L.,
“Quantitative measurement of allele-specific protein expression in a diploid yeast hybrid by LC-MS.”,
Mol Syst Biol, vol. 8, p. 602, 2012.
Evolution, Molecular
Y. Guan, Dunham, M. J., Troyanskaya, O. G., and Caudy, A. A.,
“Comparative gene expression between two yeast species.”,
BMC Genomics, vol. 14, p. 33, 2013.
Escherichia coli
Z. Khan, Amini, S., Bloom, J. S., Ruse, C., Caudy, A. A., Kruglyak, L., Singh, M., Perlman, D. H., and Tavazoie, S.,
“Accurate proteome-wide protein quantification from high-resolution 15N mass spectra.”,
Genome Biol, vol. 12, no. 12, p. R122, 2011.
Epistasis, Genetic
M. Costanzo, VanderSluis, B., Koch, E. N., Baryshnikova, A., Pons, C., Tan, G., Wang, W., Usaj, M., Hanchard, J., Lee, S. D., Pelechano, V., Styles, E. B., Billmann, M., van Leeuwen, J., van Dyk, N., Lin, Z. - Y., Kuzmin, E., Nelson, J., Piotrowski, J. S., Srikumar, T., Bahr, S., Chen, Y., Deshpande, R., Kurat, C. F., Li, S. C., Li, Z., Usaj, M. Mattiazzi, Okada, H., Pascoe, N., San Luis, B. - J., Sharifpoor, S., Shuteriqi, E., Simpkins, S. W., Snider, J., Suresh, H. Garadi, Tan, Y., Zhu, H., Malod-Dognin, N., Janjic, V., Przulj, N., Troyanskaya, O. G., Stagljar, I., Xia, T., Ohya, Y., Gingras, A. - C., Raught, B., Boutros, M., Steinmetz, L. M., Moore, C. L., Rosebrock, A. P., Caudy, A. A., Myers, C. L., Andrews, B., and Boone, C.,
“A global genetic interaction network maps a wiring diagram of cellular function.”,
Science, vol. 353, no. 6306, 2016.
DNA, Fungal
J. S. Bloom, Khan, Z., Kruglyak, L., Singh, M., and Caudy, A. A.,
“Measuring differential gene expression by short read sequencing: quantitative comparison to 2-channel gene expression microarrays.”,
BMC Genomics, vol. 10, p. 221, 2009.
DNA, Complementary
J. S. Bloom, Khan, Z., Kruglyak, L., Singh, M., and Caudy, A. A.,
“Measuring differential gene expression by short read sequencing: quantitative comparison to 2-channel gene expression microarrays.”,
BMC Genomics, vol. 10, p. 221, 2009.
DNA Primers
P. A. Gibney, Lu, C., Caudy, A. A., Hess, D. C., and Botstein, D.,
“Yeast metabolic and signaling genes are required for heat-shock survival and have little overlap with the heat-induced genes.”,
Proc Natl Acad Sci U S A, vol. 110, no. 46, pp. E4393-402, 2013.
DNA Barcoding, Taxonomic
P. A. Gibney, Lu, C., Caudy, A. A., Hess, D. C., and Botstein, D.,
“Yeast metabolic and signaling genes are required for heat-shock survival and have little overlap with the heat-induced genes.”,
Proc Natl Acad Sci U S A, vol. 110, no. 46, pp. E4393-402, 2013.
Databases, Protein
C. Huttenhower, Hibbs, M. A., Myers, C. L., Caudy, A. A., Hess, D. C., and Troyanskaya, O. G.,
“The impact of incomplete knowledge on evaluation: an experimental benchmark for protein function prediction.”,
Bioinformatics, vol. 25, no. 18, pp. 2404-10, 2009.
Cytoplasm
D. C. Hess, Myers, C. L., Huttenhower, C., Hibbs, M. A., Hayes, A. P., Paw, J., Clore, J. J., Mendoza, R. M., San Luis, B., Nislow, C., Giaever, G., Costanzo, M., Troyanskaya, O. G., and Caudy, A. A.,
“Computationally driven, quantitative experiments discover genes required for mitochondrial biogenesis.”,
PLoS Genet, vol. 5, no. 3, p. e1000407, 2009.
Cyclic AMP-Dependent Protein Kinases
Y. - F. Xu, Létisse, F., Absalan, F., Lu, W., Kuznetsova, E., Brown, G., Caudy, A. A., Yakunin, A. F., Broach, J. R., and Rabinowitz, J. D.,
“Nucleotide degradation and ribose salvage in yeast.”,
Mol Syst Biol, vol. 9, p. 665, 2013.
Crystallography, X-Ray
M. F. Clasquin, Melamud, E., Singer, A., Gooding, J. R., Xu, X., Dong, A., Cui, H., Campagna, S. R., Savchenko, A., Yakunin, A. F., Rabinowitz, J. D., and Caudy, A. A.,
“Riboneogenesis in yeast.”,
Cell, vol. 145, no. 6, pp. 969-80, 2011.
Computer Simulation
M. A. Hibbs, Myers, C. L., Huttenhower, C., Hess, D. C., Li, K., Caudy, A. A., and Troyanskaya, O. G.,
“Directing experimental biology: a case study in mitochondrial biogenesis.”,
PLoS Comput Biol, vol. 5, no. 3, p. e1000322, 2009.
E. M. Airoldi, Huttenhower, C., Gresham, D., Lu, C., Caudy, A. A., Dunham, M. J., Broach, J. R., Botstein, D., and Troyanskaya, O. G.,
“Predicting cellular growth from gene expression signatures.”,
PLoS Comput Biol, vol. 5, no. 1, p. e1000257, 2009.
Computational Biology
C. Huttenhower, Hibbs, M. A., Myers, C. L., Caudy, A. A., Hess, D. C., and Troyanskaya, O. G.,
“The impact of incomplete knowledge on evaluation: an experimental benchmark for protein function prediction.”,
Bioinformatics, vol. 25, no. 18, pp. 2404-10, 2009.
Chromatography, Reverse-Phase
W. Lu, Clasquin, M. F., Melamud, E., Amador-Noguez, D., Caudy, A. A., and Rabinowitz, J. D.,
“Metabolomic analysis via reversed-phase ion-pairing liquid chromatography coupled to a stand alone orbitrap mass spectrometer.”,
Anal Chem, vol. 82, no. 8, pp. 3212-21, 2010.
Chromatography, Liquid
Z. Khan, Bloom, J. S., Amini, S., Singh, M., Perlman, D. H., Caudy, A. A., and Kruglyak, L.,
“Quantitative measurement of allele-specific protein expression in a diploid yeast hybrid by LC-MS.”,
Mol Syst Biol, vol. 8, p. 602, 2012.
Chromatography, High Pressure Liquid
W. Lu, Clasquin, M. F., Melamud, E., Amador-Noguez, D., Caudy, A. A., and Rabinowitz, J. D.,
“Metabolomic analysis via reversed-phase ion-pairing liquid chromatography coupled to a stand alone orbitrap mass spectrometer.”,
Anal Chem, vol. 82, no. 8, pp. 3212-21, 2010.
Cell Respiration
D. C. Hess, Myers, C. L., Huttenhower, C., Hibbs, M. A., Hayes, A. P., Paw, J., Clore, J. J., Mendoza, R. M., San Luis, B., Nislow, C., Giaever, G., Costanzo, M., Troyanskaya, O. G., and Caudy, A. A.,
“Computationally driven, quantitative experiments discover genes required for mitochondrial biogenesis.”,
PLoS Genet, vol. 5, no. 3, p. e1000407, 2009.
Cell Proliferation
E. M. Airoldi, Huttenhower, C., Gresham, D., Lu, C., Caudy, A. A., Dunham, M. J., Broach, J. R., Botstein, D., and Troyanskaya, O. G.,
“Predicting cellular growth from gene expression signatures.”,
PLoS Comput Biol, vol. 5, no. 1, p. e1000257, 2009.
Biosynthetic Pathways
M. F. Clasquin, Melamud, E., Singer, A., Gooding, J. R., Xu, X., Dong, A., Cui, H., Campagna, S. R., Savchenko, A., Yakunin, A. F., Rabinowitz, J. D., and Caudy, A. A.,
“Riboneogenesis in yeast.”,
Cell, vol. 145, no. 6, pp. 969-80, 2011.
Biology
M. A. Hibbs, Myers, C. L., Huttenhower, C., Hess, D. C., Li, K., Caudy, A. A., and Troyanskaya, O. G.,
“Directing experimental biology: a case study in mitochondrial biogenesis.”,
PLoS Comput Biol, vol. 5, no. 3, p. e1000322, 2009.
Bayes Theorem
Y. Guan, Myers, C. L., Hess, D. C., Barutcuoglu, Z., Caudy, A. A., and Troyanskaya, O. G.,
“Predicting gene function in a hierarchical context with an ensemble of classifiers.”,
Genome Biol, vol. 9 Suppl 1, p. S3, 2008.
Bacterial Proteins
Z. Khan, Amini, S., Bloom, J. S., Ruse, C., Caudy, A. A., Kruglyak, L., Singh, M., Perlman, D. H., and Tavazoie, S.,
“Accurate proteome-wide protein quantification from high-resolution 15N mass spectra.”,
Genome Biol, vol. 12, no. 12, p. R122, 2011.
Animals
Y. Guan, Myers, C. L., Hess, D. C., Barutcuoglu, Z., Caudy, A. A., and Troyanskaya, O. G.,
“Predicting gene function in a hierarchical context with an ensemble of classifiers.”,
Genome Biol, vol. 9 Suppl 1, p. S3, 2008.
AMP-Activated Protein Kinases
Y. - F. Xu, Létisse, F., Absalan, F., Lu, W., Kuznetsova, E., Brown, G., Caudy, A. A., Yakunin, A. F., Broach, J. R., and Rabinowitz, J. D.,
“Nucleotide degradation and ribose salvage in yeast.”,
Mol Syst Biol, vol. 9, p. 665, 2013.
Amino Acid Sequence
Z. Khan, Amini, S., Bloom, J. S., Ruse, C., Caudy, A. A., Kruglyak, L., Singh, M., Perlman, D. H., and Tavazoie, S.,
“Accurate proteome-wide protein quantification from high-resolution 15N mass spectra.”,
Genome Biol, vol. 12, no. 12, p. R122, 2011.
Alleles
Z. Khan, Bloom, J. S., Amini, S., Singh, M., Perlman, D. H., Caudy, A. A., and Kruglyak, L.,
“Quantitative measurement of allele-specific protein expression in a diploid yeast hybrid by LC-MS.”,
Mol Syst Biol, vol. 8, p. 602, 2012.
Algorithms
C. Huttenhower, Hibbs, M. A., Myers, C. L., Caudy, A. A., Hess, D. C., and Troyanskaya, O. G.,
“The impact of incomplete knowledge on evaluation: an experimental benchmark for protein function prediction.”,
Bioinformatics, vol. 25, no. 18, pp. 2404-10, 2009.
Y. Guan, Myers, C. L., Hess, D. C., Barutcuoglu, Z., Caudy, A. A., and Troyanskaya, O. G.,
“Predicting gene function in a hierarchical context with an ensemble of classifiers.”,
Genome Biol, vol. 9 Suppl 1, p. S3, 2008.
E. M. Airoldi, Huttenhower, C., Gresham, D., Lu, C., Caudy, A. A., Dunham, M. J., Broach, J. R., Botstein, D., and Troyanskaya, O. G.,
“Predicting cellular growth from gene expression signatures.”,
PLoS Comput Biol, vol. 5, no. 1, p. e1000257, 2009.
J. S. Bloom, Khan, Z., Kruglyak, L., Singh, M., and Caudy, A. A.,
“Measuring differential gene expression by short read sequencing: quantitative comparison to 2-channel gene expression microarrays.”,
BMC Genomics, vol. 10, p. 221, 2009.
Z. Khan, Amini, S., Bloom, J. S., Ruse, C., Caudy, A. A., Kruglyak, L., Singh, M., Perlman, D. H., and Tavazoie, S.,
“Accurate proteome-wide protein quantification from high-resolution 15N mass spectra.”,
Genome Biol, vol. 12, no. 12, p. R122, 2011.