List of Faculty Publications

Below is a list of Faculty publications imported from PubMed or manually added. By default, publications are sorted by year with titles displayed in ascending alphabetical order.
Shortcuts: Wühr, Martin | Wingreen, Ned | Wieschaus, Eric | Troyanskaya, Olga | Tilghman, Shirley | Storey, John | Singh, Mona | Shvartsman, Stanislav | Shaevitz, Joshua | Rabinowitz, Joshua | Murphy, Coleen | Levine, Michael {Levine, Michael S.} | Gregor, Thomas | Botstein, David | Bialek, William | Ayroles, Julien | Andolfatto, Peter | Akey, Joshua

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Gene Regulatory Networks
G. Tkačik, Callan, C. G., and Bialek, W., Information flow and optimization in transcriptional regulation., Proc Natl Acad Sci U S A, vol. 105, no. 34, pp. 12265-70, 2008.
A. M. Walczak, Tkačik, G., and Bialek, W., Optimizing information flow in small genetic networks. II. Feed-forward interactions., Phys Rev E Stat Nonlin Soft Matter Phys, vol. 81, no. 4 Pt 1, p. 041905, 2010.
G. Tkačik, Walczak, A. M., and Bialek, W., Optimizing information flow in small genetic networks., Phys Rev E Stat Nonlin Soft Matter Phys, vol. 80, no. 3 Pt 1, p. 031920, 2009.
J. O. Dubuis, Tkačik, G., Wieschaus, E. F., Gregor, T., and Bialek, W., Positional information, in bits., Proc Natl Acad Sci U S A, vol. 110, no. 41, pp. 16301-8, 2013.
D. Krotov, Dubuis, J. O., Gregor, T., and Bialek, W., Morphogenesis at criticality., Proc Natl Acad Sci U S A, vol. 111, no. 10, pp. 3683-8, 2014.
Gene Expression Regulation, Fungal
N. Slonim, Atwal, G. Singh, Tkačik, G., and Bialek, W., Information-based clustering., Proc Natl Acad Sci U S A, vol. 102, no. 51, pp. 18297-302, 2005.
Gene Expression Regulation, Developmental
T. Gregor, Bialek, W., van Steveninck, R. R. de Ruyte, Tank, D. W., and Wieschaus, E. F., Diffusion and scaling during early embryonic pattern formation., Proc Natl Acad Sci U S A, vol. 102, no. 51, pp. 18403-7, 2005.
J. O. Dubuis, Tkačik, G., Wieschaus, E. F., Gregor, T., and Bialek, W., Positional information, in bits., Proc Natl Acad Sci U S A, vol. 110, no. 41, pp. 16301-8, 2013.
D. Krotov, Dubuis, J. O., Gregor, T., and Bialek, W., Morphogenesis at criticality., Proc Natl Acad Sci U S A, vol. 111, no. 10, pp. 3683-8, 2014.
Gene Expression Regulation, Bacterial
W. Bialek and Setayeshgar, S., Physical limits to biochemical signaling., Proc Natl Acad Sci U S A, vol. 102, no. 29, pp. 10040-5, 2005.
Gene Expression Regulation
G. Tkačik, Walczak, A. M., and Bialek, W., Optimizing information flow in small genetic networks. III. A self-interacting gene., Phys Rev E Stat Nonlin Soft Matter Phys, vol. 85, no. 4 Pt 1, p. 041903, 2012.
G. Tkačik, Callan, C. G., and Bialek, W., Information flow and optimization in transcriptional regulation., Proc Natl Acad Sci U S A, vol. 105, no. 34, pp. 12265-70, 2008.
G. Tkačik, Walczak, A. M., and Bialek, W., Optimizing information flow in small genetic networks., Phys Rev E Stat Nonlin Soft Matter Phys, vol. 80, no. 3 Pt 1, p. 031920, 2009.
G. Tkačik, Gregor, T., and Bialek, W., The role of input noise in transcriptional regulation., PLoS One, vol. 3, no. 7, p. e2774, 2008.
G. Tkačik and Bialek, W., Diffusion, dimensionality, and noise in transcriptional regulation., Phys Rev E Stat Nonlin Soft Matter Phys, vol. 79, no. 5 Pt 1, p. 051901, 2009.
Ganglia, Invertebrate
T. L. Adelman, Bialek, W., and Olberg, R. M., The information content of receptive fields., Neuron, vol. 40, no. 4, pp. 823-33, 2003.
Fluorescence Recovery After Photobleaching
T. Gregor, Wieschaus, E. F., McGregor, A. P., Bialek, W., and Tank, D. W., Stability and nuclear dynamics of the bicoid morphogen gradient., Cell, vol. 130, no. 1, pp. 141-52, 2007.
Fixation, Ocular
L. C. Osborne, Lisberger, S. G., and Bialek, W., A sensory source for motor variation., Nature, vol. 437, no. 7057, pp. 412-6, 2005.
Feedback, Physiological
A. M. Walczak, Tkačik, G., and Bialek, W., Optimizing information flow in small genetic networks. II. Feed-forward interactions., Phys Rev E Stat Nonlin Soft Matter Phys, vol. 81, no. 4 Pt 1, p. 041905, 2010.
Evolution, Molecular
T. Mora, Walczak, A. M., Bialek, W., and Callan, C. G., Maximum entropy models for antibody diversity., Proc Natl Acad Sci U S A, vol. 107, no. 12, pp. 5405-10, 2010.
Environment
N. Slonim, Atwal, G. Singh, Tkačik, G., and Bialek, W., Information-based clustering., Proc Natl Acad Sci U S A, vol. 102, no. 51, pp. 18297-302, 2005.
Entropy
G. Tkačik, Marre, O., Amodei, D., Schneidman, E., Bialek, W., and Berry, M. J., Searching for collective behavior in a large network of sensory neurons., PLoS Comput Biol, vol. 10, no. 1, p. e1003408, 2014.
T. Mora, Walczak, A. M., Bialek, W., and Callan, C. G., Maximum entropy models for antibody diversity., Proc Natl Acad Sci U S A, vol. 107, no. 12, pp. 5405-10, 2010.
W. Bialek, Cavagna, A., Giardina, I., Mora, T., Pohl, O., Silvestri, E., Viale, M., and Walczak, A. M., Social interactions dominate speed control in poising natural flocks near criticality., Proc Natl Acad Sci U S A, vol. 111, no. 20, pp. 7212-7, 2014.
G. J. Stephens and Bialek, W., Statistical mechanics of letters in words., Phys Rev E Stat Nonlin Soft Matter Phys, vol. 81, no. 6 Pt 2, p. 066119, 2010.
W. Bialek, Cavagna, A., Giardina, I., Mora, T., Silvestri, E., Viale, M., and Walczak, A. M., Statistical mechanics for natural flocks of birds., Proc Natl Acad Sci U S A, vol. 109, no. 13, pp. 4786-91, 2012.
T. Sharpee and Bialek, W., Neural decision boundaries for maximal information transmission., PLoS One, vol. 2, no. 7, p. e646, 2007.
E. Schneidman, Berry, M. J., Segev, R., and Bialek, W., Weak pairwise correlations imply strongly correlated network states in a neural population., Nature, vol. 440, no. 7087, pp. 1007-12, 2006.
G. J. Stephens, Osborne, L. C., and Bialek, W., Searching for simplicity in the analysis of neurons and behavior., Proc Natl Acad Sci U S A, vol. 108 Suppl 3, pp. 15565-71, 2011.
Embryonic Development
J. O. Dubuis, Tkačik, G., Wieschaus, E. F., Gregor, T., and Bialek, W., Positional information, in bits., Proc Natl Acad Sci U S A, vol. 110, no. 41, pp. 16301-8, 2013.
W. Bialek, QnAs with William Bialek., Proc Natl Acad Sci U S A, vol. 110, no. 41, p. 16288, 2013.
Embryo, Nonmammalian
T. Gregor, Bialek, W., van Steveninck, R. R. de Ruyte, Tank, D. W., and Wieschaus, E. F., Diffusion and scaling during early embryonic pattern formation., Proc Natl Acad Sci U S A, vol. 102, no. 51, pp. 18403-7, 2005.
D. Krotov, Dubuis, J. O., Gregor, T., and Bialek, W., Morphogenesis at criticality., Proc Natl Acad Sci U S A, vol. 111, no. 10, pp. 3683-8, 2014.
Efferent Pathways
T. L. Adelman, Bialek, W., and Olberg, R. M., The information content of receptive fields., Neuron, vol. 40, no. 4, pp. 823-33, 2003.
Drosophila Proteins
T. Gregor, Tank, D. W., Wieschaus, E. F., and Bialek, W., Probing the limits to positional information., Cell, vol. 130, no. 1, pp. 153-64, 2007.
G. Tkačik, Callan, C. G., and Bialek, W., Information flow and optimization in transcriptional regulation., Proc Natl Acad Sci U S A, vol. 105, no. 34, pp. 12265-70, 2008.
D. Krotov, Dubuis, J. O., Gregor, T., and Bialek, W., Morphogenesis at criticality., Proc Natl Acad Sci U S A, vol. 111, no. 10, pp. 3683-8, 2014.
Drosophila
G. Tkačik, Callan, C. G., and Bialek, W., Information flow and optimization in transcriptional regulation., Proc Natl Acad Sci U S A, vol. 105, no. 34, pp. 12265-70, 2008.
G. Tkačik, Gregor, T., and Bialek, W., The role of input noise in transcriptional regulation., PLoS One, vol. 3, no. 7, p. e2774, 2008.
J. O. Dubuis, Tkačik, G., Wieschaus, E. F., Gregor, T., and Bialek, W., Positional information, in bits., Proc Natl Acad Sci U S A, vol. 110, no. 41, pp. 16301-8, 2013.
D. Krotov, Dubuis, J. O., Gregor, T., and Bialek, W., Morphogenesis at criticality., Proc Natl Acad Sci U S A, vol. 111, no. 10, pp. 3683-8, 2014.
DNA-Binding Proteins
D. Krotov, Dubuis, J. O., Gregor, T., and Bialek, W., Morphogenesis at criticality., Proc Natl Acad Sci U S A, vol. 111, no. 10, pp. 3683-8, 2014.
G. Tkačik, Callan, C. G., and Bialek, W., Information flow and optimization in transcriptional regulation., Proc Natl Acad Sci U S A, vol. 105, no. 34, pp. 12265-70, 2008.
T. Gregor, Tank, D. W., Wieschaus, E. F., and Bialek, W., Probing the limits to positional information., Cell, vol. 130, no. 1, pp. 153-64, 2007.
DNA
G. Tkačik and Bialek, W., Diffusion, dimensionality, and noise in transcriptional regulation., Phys Rev E Stat Nonlin Soft Matter Phys, vol. 79, no. 5 Pt 1, p. 051901, 2009.
T. Mora, Walczak, A. M., Bialek, W., and Callan, C. G., Maximum entropy models for antibody diversity., Proc Natl Acad Sci U S A, vol. 107, no. 12, pp. 5405-10, 2010.
Discrimination Learning
L. C. Osborne, Lisberger, S. G., and Bialek, W., A sensory source for motor variation., Nature, vol. 437, no. 7057, pp. 412-6, 2005.
Cluster Analysis
N. Slonim, Atwal, G. Singh, Tkačik, G., and Bialek, W., Information-based clustering., Proc Natl Acad Sci U S A, vol. 102, no. 51, pp. 18297-302, 2005.
Chemotaxis
W. Bialek and Setayeshgar, S., Physical limits to biochemical signaling., Proc Natl Acad Sci U S A, vol. 102, no. 29, pp. 10040-5, 2005.
Cells
G. Tkačik, Walczak, A. M., and Bialek, W., Optimizing information flow in small genetic networks., Phys Rev E Stat Nonlin Soft Matter Phys, vol. 80, no. 3 Pt 1, p. 031920, 2009.
Cell Movement
J. O. Dubuis, Tkačik, G., Wieschaus, E. F., Gregor, T., and Bialek, W., Positional information, in bits., Proc Natl Acad Sci U S A, vol. 110, no. 41, pp. 16301-8, 2013.
Biophysics
W. Bialek, QnAs with William Bialek., Proc Natl Acad Sci U S A, vol. 110, no. 41, p. 16288, 2013.
G. Tkačik, Callan, C. G., and Bialek, W., Information capacity of genetic regulatory elements., Phys Rev E Stat Nonlin Soft Matter Phys, vol. 78, no. 1 Pt 1, p. 011910, 2008.
N. Brenner, Agam, O., Bialek, W., and van Steveninck, Rde Ruyter, Statistical properties of spike trains: universal and stimulus-dependent aspects., Phys Rev E Stat Nonlin Soft Matter Phys, vol. 66, no. 3 Pt 1, p. 031907, 2002.
W. Bialek and Setayeshgar, S., Physical limits to biochemical signaling., Proc Natl Acad Sci U S A, vol. 102, no. 29, pp. 10040-5, 2005.
Biophysical Phenomena
T. Mora, Walczak, A. M., Bialek, W., and Callan, C. G., Maximum entropy models for antibody diversity., Proc Natl Acad Sci U S A, vol. 107, no. 12, pp. 5405-10, 2010.
N. Brenner, Agam, O., Bialek, W., and van Steveninck, Rde Ruyter, Statistical properties of spike trains: universal and stimulus-dependent aspects., Phys Rev E Stat Nonlin Soft Matter Phys, vol. 66, no. 3 Pt 1, p. 031907, 2002.
W. Bialek and Setayeshgar, S., Physical limits to biochemical signaling., Proc Natl Acad Sci U S A, vol. 102, no. 29, pp. 10040-5, 2005.
Biomechanical Phenomena
W. Bialek, Cavagna, A., Giardina, I., Mora, T., Silvestri, E., Viale, M., and Walczak, A. M., Statistical mechanics for natural flocks of birds., Proc Natl Acad Sci U S A, vol. 109, no. 13, pp. 4786-91, 2012.
Biological Science Disciplines
W. Bialek and Botstein, D., Introductory science and mathematics education for 21st-Century biologists., Science, vol. 303, no. 5659, pp. 788-90, 2004.
Biological Evolution
D. Krotov, Dubuis, J. O., Gregor, T., and Bialek, W., Morphogenesis at criticality., Proc Natl Acad Sci U S A, vol. 111, no. 10, pp. 3683-8, 2014.
Binding Sites
W. Bialek and Setayeshgar, S., Cooperativity, sensitivity, and noise in biochemical signaling., Phys Rev Lett, vol. 100, no. 25, p. 258101, 2008.
Behavior
G. J. Stephens, Osborne, L. C., and Bialek, W., Searching for simplicity in the analysis of neurons and behavior., Proc Natl Acad Sci U S A, vol. 108 Suppl 3, pp. 15565-71, 2011.
Base Sequence
T. Mora, Walczak, A. M., Bialek, W., and Callan, C. G., Maximum entropy models for antibody diversity., Proc Natl Acad Sci U S A, vol. 107, no. 12, pp. 5405-10, 2010.
Bacterial Physiological Phenomena
W. Bialek and Setayeshgar, S., Physical limits to biochemical signaling., Proc Natl Acad Sci U S A, vol. 102, no. 29, pp. 10040-5, 2005.
Automatic Data Processing
T. Sharpee and Bialek, W., Neural decision boundaries for maximal information transmission., PLoS One, vol. 2, no. 7, p. e646, 2007.
Antibody Diversity
T. Mora, Walczak, A. M., Bialek, W., and Callan, C. G., Maximum entropy models for antibody diversity., Proc Natl Acad Sci U S A, vol. 107, no. 12, pp. 5405-10, 2010.
Animals
L. C. Osborne, Hohl, S. S., Bialek, W., and Lisberger, S. G., Time course of precision in smooth-pursuit eye movements of monkeys., J Neurosci, vol. 27, no. 11, pp. 2987-98, 2007.
G. Tkačik, Walczak, A. M., and Bialek, W., Optimizing information flow in small genetic networks. III. A self-interacting gene., Phys Rev E Stat Nonlin Soft Matter Phys, vol. 85, no. 4 Pt 1, p. 041903, 2012.
G. Tkačik, Callan, C. G., and Bialek, W., Information flow and optimization in transcriptional regulation., Proc Natl Acad Sci U S A, vol. 105, no. 34, pp. 12265-70, 2008.
T. Gregor, Tank, D. W., Wieschaus, E. F., and Bialek, W., Probing the limits to positional information., Cell, vol. 130, no. 1, pp. 153-64, 2007.
G. Tkačik, Marre, O., Amodei, D., Schneidman, E., Bialek, W., and Berry, M. J., Searching for collective behavior in a large network of sensory neurons., PLoS Comput Biol, vol. 10, no. 1, p. e1003408, 2014.
I. Nemenman, Lewen, G. D., Bialek, W., and van Steveninck, R. R. de Ruyte, Neural coding of natural stimuli: information at sub-millisecond resolution., PLoS Comput Biol, vol. 4, no. 3, p. e1000025, 2008.
G. J. Stephens, Johnson-Kerner, B., Bialek, W., and Ryu, W. S., From modes to movement in the behavior of Caenorhabditis elegans., PLoS One, vol. 5, no. 11, p. e13914, 2010.
T. Gregor, Bialek, W., van Steveninck, R. R. de Ruyte, Tank, D. W., and Wieschaus, E. F., Diffusion and scaling during early embryonic pattern formation., Proc Natl Acad Sci U S A, vol. 102, no. 51, pp. 18403-7, 2005.
T. Mora, Walczak, A. M., Bialek, W., and Callan, C. G., Maximum entropy models for antibody diversity., Proc Natl Acad Sci U S A, vol. 107, no. 12, pp. 5405-10, 2010.
N. Brenner, Agam, O., Bialek, W., and van Steveninck, Rde Ruyter, Statistical properties of spike trains: universal and stimulus-dependent aspects., Phys Rev E Stat Nonlin Soft Matter Phys, vol. 66, no. 3 Pt 1, p. 031907, 2002.
W. Bialek, Cavagna, A., Giardina, I., Mora, T., Pohl, O., Silvestri, E., Viale, M., and Walczak, A. M., Social interactions dominate speed control in poising natural flocks near criticality., Proc Natl Acad Sci U S A, vol. 111, no. 20, pp. 7212-7, 2014.
L. C. Osborne, Bialek, W., and Lisberger, S. G., Time course of information about motion direction in visual area MT of macaque monkeys., J Neurosci, vol. 24, no. 13, pp. 3210-22, 2004.
T. L. Adelman, Bialek, W., and Olberg, R. M., The information content of receptive fields., Neuron, vol. 40, no. 4, pp. 823-33, 2003.
L. C. Osborne, Palmer, S. E., Lisberger, S. G., and Bialek, W., The neural basis for combinatorial coding in a cortical population response., J Neurosci, vol. 28, no. 50, pp. 13522-31, 2008.
G. Tkačik, Walczak, A. M., and Bialek, W., Optimizing information flow in small genetic networks., Phys Rev E Stat Nonlin Soft Matter Phys, vol. 80, no. 3 Pt 1, p. 031920, 2009.
G. J. Stephens, de Mesquita, M. Bueno, Ryu, W. S., and Bialek, W., Emergence of long timescales and stereotyped behaviors in Caenorhabditis elegans., Proc Natl Acad Sci U S A, vol. 108, no. 18, pp. 7286-9, 2011.
G. Tkačik, Gregor, T., and Bialek, W., The role of input noise in transcriptional regulation., PLoS One, vol. 3, no. 7, p. e2774, 2008.
L. C. Osborne, Lisberger, S. G., and Bialek, W., A sensory source for motor variation., Nature, vol. 437, no. 7057, pp. 412-6, 2005.
J. O. Dubuis, Tkačik, G., Wieschaus, E. F., Gregor, T., and Bialek, W., Positional information, in bits., Proc Natl Acad Sci U S A, vol. 110, no. 41, pp. 16301-8, 2013.
E. Schneidman, Bialek, W., and Berry, M. J., Synergy, redundancy, and independence in population codes., J Neurosci, vol. 23, no. 37, pp. 11539-53, 2003.
W. Bialek, Cavagna, A., Giardina, I., Mora, T., Silvestri, E., Viale, M., and Walczak, A. M., Statistical mechanics for natural flocks of birds., Proc Natl Acad Sci U S A, vol. 109, no. 13, pp. 4786-91, 2012.
T. Sharpee and Bialek, W., Neural decision boundaries for maximal information transmission., PLoS One, vol. 2, no. 7, p. e646, 2007.
T. Sharpee, Rust, N. C., and Bialek, W., Analyzing neural responses to natural signals: maximally informative dimensions., Neural Comput, vol. 16, no. 2, pp. 223-50, 2004.
E. Schneidman, Berry, M. J., Segev, R., and Bialek, W., Weak pairwise correlations imply strongly correlated network states in a neural population., Nature, vol. 440, no. 7087, pp. 1007-12, 2006.
G. J. Stephens, Johnson-Kerner, B., Bialek, W., and Ryu, W. S., Dimensionality and dynamics in the behavior of C. elegans., PLoS Comput Biol, vol. 4, no. 4, p. e1000028, 2008.
E. Schneidman, Puchalla, J. L., Segev, R., Harris, R. A., Bialek, W., and Berry, M. J., Synergy from silence in a combinatorial neural code., J Neurosci, vol. 31, no. 44, pp. 15732-41, 2011.
D. Krotov, Dubuis, J. O., Gregor, T., and Bialek, W., Morphogenesis at criticality., Proc Natl Acad Sci U S A, vol. 111, no. 10, pp. 3683-8, 2014.
G. Tkačik, Callan, C. G., and Bialek, W., Information capacity of genetic regulatory elements., Phys Rev E Stat Nonlin Soft Matter Phys, vol. 78, no. 1 Pt 1, p. 011910, 2008.
T. Gregor, Wieschaus, E. F., McGregor, A. P., Bialek, W., and Tank, D. W., Stability and nuclear dynamics of the bicoid morphogen gradient., Cell, vol. 130, no. 1, pp. 141-52, 2007.
G. J. Stephens, Osborne, L. C., and Bialek, W., Searching for simplicity in the analysis of neurons and behavior., Proc Natl Acad Sci U S A, vol. 108 Suppl 3, pp. 15565-71, 2011.
Amino Acid Sequence
T. Mora, Walczak, A. M., Bialek, W., and Callan, C. G., Maximum entropy models for antibody diversity., Proc Natl Acad Sci U S A, vol. 107, no. 12, pp. 5405-10, 2010.
Action Potentials
G. Tkačik, Marre, O., Amodei, D., Schneidman, E., Bialek, W., and Berry, M. J., Searching for collective behavior in a large network of sensory neurons., PLoS Comput Biol, vol. 10, no. 1, p. e1003408, 2014.
I. Nemenman, Lewen, G. D., Bialek, W., and van Steveninck, R. R. de Ruyte, Neural coding of natural stimuli: information at sub-millisecond resolution., PLoS Comput Biol, vol. 4, no. 3, p. e1000025, 2008.
L. C. Osborne, Bialek, W., and Lisberger, S. G., Time course of information about motion direction in visual area MT of macaque monkeys., J Neurosci, vol. 24, no. 13, pp. 3210-22, 2004.
T. L. Adelman, Bialek, W., and Olberg, R. M., The information content of receptive fields., Neuron, vol. 40, no. 4, pp. 823-33, 2003.
B. Agüera y Arcas, Fairhall, A. L., and Bialek, W., Computation in a single neuron: Hodgkin and Huxley revisited., Neural Comput, vol. 15, no. 8, pp. 1715-49, 2003.
E. Schneidman, Bialek, W., and Berry, M. J., Synergy, redundancy, and independence in population codes., J Neurosci, vol. 23, no. 37, pp. 11539-53, 2003.
E. Schneidman, Berry, M. J., Segev, R., and Bialek, W., Weak pairwise correlations imply strongly correlated network states in a neural population., Nature, vol. 440, no. 7087, pp. 1007-12, 2006.
T. Sharpee, Rust, N. C., and Bialek, W., Analyzing neural responses to natural signals: maximally informative dimensions., Neural Comput, vol. 16, no. 2, pp. 223-50, 2004.
E. Schneidman, Puchalla, J. L., Segev, R., Harris, R. A., Bialek, W., and Berry, M. J., Synergy from silence in a combinatorial neural code., J Neurosci, vol. 31, no. 44, pp. 15732-41, 2011.

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