List of Faculty Publications

Below is a list of Faculty publications imported from PubMed or manually added. By default, publications are sorted by year with titles displayed in ascending alphabetical order.
Shortcuts: Wühr, Martin | Wingreen, Ned | Wieschaus, Eric | Troyanskaya, Olga | Tilghman, Shirley | Storey, John | Singh, Mona | Shvartsman, Stanislav | Shaevitz, Joshua | Rabinowitz, Joshua | Murphy, Coleen | Levine, Michael {Levine, Michael S.} | Gregor, Thomas | Botstein, David | Bialek, William | Ayroles, Julien | Andolfatto, Peter | Akey, Joshua

2011
Z. Khan, Amini, S., Bloom, J. S., Ruse, C., Caudy, A. A., Kruglyak, L., Singh, M., Perlman, D. H., and Tavazoie, S., Accurate proteome-wide protein quantification from high-resolution 15N mass spectra., Genome Biol, vol. 12, no. 12, p. R122, 2011.
M. D. Chikina and Troyanskaya, O. G., Accurate quantification of functional analogy among close homologs., PLoS Comput Biol, vol. 7, no. 2, p. e1001074, 2011.
D. Swanson and Wingreen, N. S., Active biopolymers confer fast reorganization kinetics., Phys Rev Lett, vol. 107, no. 21, p. 218103, 2011.
S. - W. Teng, Schaffer, J. N., Tu, K. C., Mehta, P., Lu, W., Ong, N. P., Bassler, B. L., and Wingreen, N. S., Active regulation of receptor ratios controls integration of quorum-sensing signals in Vibrio harveyi., Mol Syst Biol, vol. 7, p. 491, 2011.
S. van Teeffelen, Wang, S., Furchtgott, L., Huang, K. Casey, Wingreen, N. S., Shaevitz, J. W., and Gitai, Z., The bacterial actin MreB rotates, and rotation depends on cell-wall assembly., Proc Natl Acad Sci U S A, vol. 108, no. 38, pp. 15822-7, 2011.
S. Luo and Murphy, C. T., Caenorhabditis elegans reproductive aging: Regulation and underlying mechanisms., Genesis, vol. 49, no. 2, pp. 53-65, 2011.
M. Louis Reaves and Rabinowitz, J. D., Characteristic phenotypes associated with ptsN-null mutants in Escherichia coli K-12 are absent in strains with functional ilvG., J Bacteriol, vol. 193, no. 18, pp. 4576-81, 2011.
D. Papatsenko, Levine, M., and Goltsev, Y., Clusters of temporal discordances reveal distinct embryonic patterning mechanisms in Drosophila and anopheles., PLoS Biol, vol. 9, no. 1, p. e1000584, 2011.
J. S. Kanodia, Kim, Y., Tomer, R., Khan, Z., Chung, K., Storey, J. D., Lu, H., Keller, P. J., and Shvartsman, S. Y., A computational statistics approach for estimating the spatial range of morphogen gradients., Development, vol. 138, no. 22, pp. 4867-74, 2011.
M. J. Hickman, Petti, A. A., Ho-Shing, O., Silverman, S. J., R McIsaac, S., Lee, T. A., and Botstein, D., Coordinated regulation of sulfur and phospholipid metabolism reflects the importance of methylation in the growth of yeast., Mol Biol Cell, vol. 22, no. 21, pp. 4192-204, 2011.
B. Callahan, Neher, R. A., Bachtrog, D., Andolfatto, P., and Shraiman, B. I., Correlated evolution of nearby residues in Drosophilid proteins., PLoS Genet, vol. 7, no. 2, p. e1001315, 2011.
N. Slavov and Botstein, D., Coupling among growth rate response, metabolic cycle, and cell division cycle in yeast., Mol Biol Cell, vol. 22, no. 12, pp. 1997-2009, 2011.
A. Pane, Jiang, P., Zhao, D. Yanling, Singh, M., and Schüpbach, T., The Cutoff protein regulates piRNA cluster expression and piRNA production in the Drosophila germline., EMBO J, vol. 30, no. 22, pp. 4601-15, 2011.
Y. Deng, Sun, M., and Shaevitz, J. W., Direct measurement of cell wall stress stiffening and turgor pressure in live bacterial cells., Phys Rev Lett, vol. 107, no. 15, p. 158101, 2011.
K. H. Desai, Tan, C. Seng, Leek, J. T., Maier, R. V., Tompkins, R. G., and Storey, J. D., Dissecting inflammatory complications in critically injured patients by within-patient gene expression changes: a longitudinal clinical genomics study., PLoS Med, vol. 8, no. 9, p. e1001093, 2011.
L. Vastag, Koyuncu, E., Grady, S. L., Shenk, T. E., and Rabinowitz, J. D., Divergent effects of human cytomegalovirus and herpes simplex virus-1 on cellular metabolism., PLoS Pathog, vol. 7, no. 7, p. e1002124, 2011.
S. R McIsaac, Huang, K. Casey, Sengupta, A., and Wingreen, N. S., Does the potential for chaos constrain the embryonic cell-cycle oscillator?, PLoS Comput Biol, vol. 7, no. 7, p. e1002109, 2011.
M. Skoge, Meir, Y., and Wingreen, N. S., Dynamics of cooperativity in chemical sensing among cell-surface receptors., Phys Rev Lett, vol. 107, no. 17, p. 178101, 2011.
P. Andolfatto, Wong, K. M., and Bachtrog, D., Effective population size and the efficacy of selection on the X chromosomes of two closely related Drosophila species., Genome Biol Evol, vol. 3, pp. 114-28, 2011.
G. Liu, Rogers, J., Murphy, C. T., and Rongo, C., EGF signalling activates the ubiquitin proteasome system to modulate C. elegans lifespan., EMBO J, vol. 30, no. 15, pp. 2990-3003, 2011.
G. J. Stephens, de Mesquita, M. Bueno, Ryu, W. S., and Bialek, W., Emergence of long timescales and stereotyped behaviors in Caenorhabditis elegans., Proc Natl Acad Sci U S A, vol. 108, no. 18, pp. 7286-9, 2011.
G. Rizki, Iwata, T. Naoko, Li, J., Riedel, C. G., Picard, C. Lafontaine, Jan, M., Murphy, C. T., and Lee, S. Sylvia, The evolutionarily conserved longevity determinants HCF-1 and SIR-2.1/SIRT1 collaborate to regulate DAF-16/FOXO., PLoS Genet, vol. 7, no. 9, p. e1002235, 2011.
A. V. Persikov and Singh, M., An expanded binding model for Cys2His2 zinc finger protein-DNA interfaces., Phys Biol, vol. 8, no. 3, p. 035010, 2011.
S. R McIsaac, Silverman, S. J., McClean, M. N., Gibney, P. A., Macinskas, J., Hickman, M. J., Petti, A. A., and Botstein, D., Fast-acting and nearly gratuitous induction of gene expression and protein depletion in Saccharomyces cerevisiae., Mol Biol Cell, vol. 22, no. 22, pp. 4447-59, 2011.
E. J. Banigan, Gelbart, M. A., Gitai, Z., Wingreen, N. S., and Liu, A. J., Filament depolymerization can explain chromosome pulling during bacterial mitosis., PLoS Comput Biol, vol. 7, no. 9, p. e1002145, 2011.
A. M. Berezhkovskii, Sample, C., and Shvartsman, S. Y., Formation of morphogen gradients: local accumulation time., Phys Rev E Stat Nonlin Soft Matter Phys, vol. 83, no. 5 Pt 1, p. 051906, 2011.
S. C. Little, Tkačik, G., Kneeland, T. B., Wieschaus, E. F., and Gregor, T., The formation of the Bicoid morphogen gradient requires protein movement from anteriorly localized mRNA., PLoS Biol, vol. 9, no. 3, p. e1000596, 2011.
J. F. Ayroles, Laflamme, B. A., Stone, E. A., Wolfner, M. F., and Mackay, T. F. C., Functional genome annotation of Drosophila seminal fluid proteins using transcriptional genetic networks., Genet Res (Camb), vol. 93, no. 6, pp. 387-95, 2011.
Y. Kim, Andreu, M. José, Lim, B., Chung, K., Terayama, M., Jiménez, G., Berg, C. A., Lu, H., and Shvartsman, S. Y., Gene regulation by MAPK substrate competition., Dev Cell, vol. 20, no. 6, pp. 880-7, 2011.
G. I. Lang, Botstein, D., and Desai, M. M., Genetic variation and the fate of beneficial mutations in asexual populations., Genetics, vol. 188, no. 3, pp. 647-61, 2011.
D. Botstein, Genome-sequencing anniversary. Fruits of genome sequences for biology., Science, vol. 331, no. 6020, p. 1025, 2011.
J. J. Kamphorst, Fan, J., Lu, W., White, E., and Rabinowitz, J. D., Liquid chromatography-high resolution mass spectrometry analysis of fatty acid metabolism., Anal Chem, vol. 83, no. 23, pp. 9114-22, 2011.
P. V. Gordon, Sample, C., Berezhkovskii, A. M., Muratov, C. B., and Shvartsman, S. Y., Local kinetics of morphogen gradients., Proc Natl Acad Sci U S A, vol. 108, no. 15, pp. 6157-62, 2011.
J. A. Drocco, Grimm, O., Tank, D. W., and Wieschaus, E., Measurement and perturbation of morphogen lifetime: effects on gradient shape., Biophys J, vol. 101, no. 8, pp. 1807-15, 2011.
K. E. Daly, Huang, K. Casey, Wingreen, N. S., and Mukhopadhyay, R., Mechanics of membrane bulging during cell-wall disruption in gram-negative bacteria., Phys Rev E Stat Nonlin Soft Matter Phys, vol. 83, no. 4 Pt 1, p. 041922, 2011.
L. Furchtgott, Wingreen, N. S., and Huang, K. Casey, Mechanisms for maintaining cell shape in rod-shaped Gram-negative bacteria., Mol Microbiol, vol. 81, no. 2, pp. 340-53, 2011.
N. Slavov, Macinskas, J., Caudy, A., and Botstein, D., Metabolic cycling without cell division cycling in respiring yeast., Proc Natl Acad Sci U S A, vol. 108, no. 47, pp. 19090-5, 2011.
D. Amador-Noguez, Brasg, I. A., Feng, X. - J., Roquet, N., and Rabinowitz, J. D., Metabolome remodeling during the acidogenic-solventogenic transition in Clostridium acetobutylicum., Appl Environ Microbiol, vol. 77, no. 22, pp. 7984-97, 2011.
M. Louis Reaves and Rabinowitz, J. D., Metabolomics in systems microbiology., Curr Opin Biotechnol, vol. 22, no. 1, pp. 17-25, 2011.
K. Chung, Kim, Y., Kanodia, J. S., Gong, E., Shvartsman, S. Y., and Lu, H., A microfluidic array for large-scale ordering and orientation of embryos., Nat Methods, vol. 8, no. 2, pp. 171-6, 2011.
M. Sun, Wartel, M., Cascales, E., Shaevitz, J. W., and Mignot, T., Motor-driven intracellular transport powers bacterial gliding motility., Proc Natl Acad Sci U S A, vol. 108, no. 18, pp. 7559-64, 2011.
M. W. Perry, Boettiger, A. N., and Levine, M., Multiple enhancers ensure precision of gap gene-expression patterns in the Drosophila embryo., Proc Natl Acad Sci U S A, vol. 108, no. 33, pp. 13570-5, 2011.
P. Andolfatto, Davison, D., Erezyilmaz, D., Hu, T. T., Mast, J., Sunayama-Morita, T., and Stern, D. L., Multiplexed shotgun genotyping for rapid and efficient genetic mapping., Genome Res, vol. 21, no. 4, pp. 610-7, 2011.
K. C. Rowe, Singhal, S., Macmanes, M. D., Ayroles, J. F., Morelli, T. Lyn, Rubidge, E. M., Bi, K., and Moritz, C. C., Museum genomics: low-cost and high-accuracy genetic data from historical specimens., Mol Ecol Resour, vol. 11, no. 6, pp. 1082-92, 2011.
A. Stolfi, Wagner, E., J Taliaferro, M., Chou, S., and Levine, M., Neural tube patterning by Ephrin, FGF and Notch signaling relays., Development, vol. 138, no. 24, pp. 5429-39, 2011.
V. Hilgers, Perry, M. W., Hendrix, D., Stark, A., Levine, M., and Haley, B., Neural-specific elongation of 3' UTRs during Drosophila development., Proc Natl Acad Sci U S A, vol. 108, no. 38, pp. 15864-9, 2011.
A. Stolfi and Levine, M., Neuronal subtype specification in the spinal cord of a protovertebrate., Development, vol. 138, no. 5, pp. 995-1004, 2011.
T. Mora, Bai, F., Che, Y. - S., Minamino, T., Namba, K., and Wingreen, N. S., Non-genetic individuality in Escherichia coli motor switching., Phys Biol, vol. 8, no. 2, p. 024001, 2011.
Y. Guan, Yao, V., Tsui, K., Gebbia, M., Dunham, M. J., Nislow, C., and Troyanskaya, O. G., Nucleosome-coupled expression differences in closely-related species., BMC Genomics, vol. 12, p. 466, 2011.
J. J. Zartman, Cheung, L. S., Niepielko, M. G., Bonini, C., Haley, B., Yakoby, N., and Shvartsman, S. Y., Pattern formation by a moving morphogen source., Phys Biol, vol. 8, no. 4, p. 045003, 2011.
L. S. Cheung, Schüpbach, T., and Shvartsman, S. Y., Pattern formation by receptor tyrosine kinases: analysis of the Gurken gradient in Drosophila oogenesis., Curr Opin Genet Dev, vol. 21, no. 6, pp. 719-25, 2011.
M. Levine, Paused RNA polymerase II as a developmental checkpoint., Cell, vol. 145, no. 4, pp. 502-11, 2011.
A. M. Berezhkovskii and Shvartsman, S. Y., Physical interpretation of mean local accumulation time of morphogen gradient formation., J Chem Phys, vol. 135, no. 15, p. 154115, 2011.
C. S. Greene and Troyanskaya, O. G., PILGRM: an interactive data-driven discovery platform for expert biologists., Nucleic Acids Res, vol. 39, no. Web Server issue, pp. W368-74, 2011.
V. S. Chopra, Hendrix, D. A., Core, L. J., Tsui, C., Lis, J. T., and Levine, M., The polycomb group mutant esc leads to augmented levels of paused Pol II in the Drosophila embryo., Mol Cell, vol. 42, no. 6, pp. 837-44, 2011.
D. J. Wilson, Hernandez, R. D., Andolfatto, P., and Przeworski, M., A population genetics-phylogenetics approach to inferring natural selection in coding sequences., PLoS Genet, vol. 7, no. 12, p. e1002395, 2011.
Y. Wang, Tu, K. C., Ong, N. P., Bassler, B. L., and Wingreen, N. S., Protein-level fluctuation correlation at the microcolony level and its application to the Vibrio harveyi quorum-sensing circuit., Biophys J, vol. 100, no. 12, pp. 3045-53, 2011.
L. Vastag, Jorgensen, P., Peshkin, L., Wei, R., Rabinowitz, J. D., and Kirschner, M. W., Remodeling of the metabolome during early frog development., PLoS One, vol. 6, no. 2, p. e16881, 2011.
M. F. Clasquin, Melamud, E., Singer, A., Gooding, J. R., Xu, X., Dong, A., Cui, H., Campagna, S. R., Savchenko, A., Yakunin, A. F., Rabinowitz, J. D., and Caudy, A. A., Riboneogenesis in yeast., Cell, vol. 145, no. 6, pp. 969-80, 2011.
G. J. Stephens, Osborne, L. C., and Bialek, W., Searching for simplicity in the analysis of neurons and behavior., Proc Natl Acad Sci U S A, vol. 108 Suppl 3, pp. 15565-71, 2011.
C. B. Muratov, Gordon, P. V., and Shvartsman, S. Y., Self-similar dynamics of morphogen gradients., Phys Rev E Stat Nonlin Soft Matter Phys, vol. 84, no. 4 Pt 1, p. 041916, 2011.
S. C. Little and Wieschaus, E. F., Shifting patterns: merging molecules, morphogens, motility, and methodology., Dev Cell, vol. 21, no. 1, pp. 2-4, 2011.
J. P. Bothma, Magliocco, J., and Levine, M., The snail repressor inhibits release, not elongation, of paused Pol II in the Drosophila embryo., Curr Biol, vol. 21, no. 18, pp. 1571-7, 2011.
J. P. Huelsenbeck, Andolfatto, P., and Huelsenbeck, E. T., Structurama: bayesian inference of population structure., Evol Bioinform Online, vol. 7, pp. 55-9, 2011.
P. Liu, Kevrekidis, I. G., and Shvartsman, S. Y., Substrate-dependent control of ERK phosphorylation can lead to oscillations., Biophys J, vol. 101, no. 11, pp. 2572-81, 2011.
Y. Kim, Paroush, Z. 'ev, Nairz, K., Hafen, E., Jiménez, G., and Shvartsman, S. Y., Substrate-dependent control of MAPK phosphorylation in vivo., Mol Syst Biol, vol. 7, p. 467, 2011.
A. A. Petti, Crutchfield, C. A., Rabinowitz, J. D., and Botstein, D., Survival of starving yeast is correlated with oxidative stress response and nonrespiratory mitochondrial function., Proc Natl Acad Sci U S A, vol. 108, no. 45, pp. E1089-98, 2011.
S. T. H. Liu, Sharon-Friling, R., Ivanova, P., Milne, S. B., Myers, D. S., Rabinowitz, J. D., H Brown, A., and Shenk, T., Synaptic vesicle-like lipidome of human cytomegalovirus virions reveals a role for SNARE machinery in virion egress., Proc Natl Acad Sci U S A, vol. 108, no. 31, pp. 12869-74, 2011.
E. Schneidman, Puchalla, J. L., Segev, R., Harris, R. A., Bialek, W., and Berry, M. J., Synergy from silence in a combinatorial neural code., J Neurosci, vol. 31, no. 44, pp. 15732-41, 2011.
D. Gresham, Boer, V. M., Caudy, A., Ziv, N., Brandt, N. J., Storey, J. D., and Botstein, D., System-level analysis of genes and functions affecting survival during nutrient starvation in Saccharomyces cerevisiae., Genetics, vol. 187, no. 1, pp. 299-317, 2011.
G. I. Lang and Botstein, D., A test of the coordinated expression hypothesis for the origin and maintenance of the GAL cluster in yeast., PLoS One, vol. 6, no. 9, p. e25290, 2011.
O. Oleksiuk, Jakovljevic, V., Vladimirov, N., Carvalho, R., Paster, E., Ryu, W. S., Meir, Y., Wingreen, N. S., Kollmann, M., and Sourjik, V., Thermal robustness of signaling in bacterial chemotaxis., Cell, vol. 145, no. 2, pp. 312-21, 2011.
A. Ochoa, Llinás, M., and Singh, M., Using context to improve protein domain identification., BMC Bioinformatics, vol. 12, p. 90, 2011.
D. Botstein and Fink, G. R., Yeast: an experimental organism for 21st Century biology., Genetics, vol. 189, no. 3, pp. 695-704, 2011.
M. M. Klosinska, Crutchfield, C. A., Bradley, P. H., Rabinowitz, J. D., and Broach, J. R., Yeast cells can access distinct quiescent states., Genes Dev, vol. 25, no. 4, pp. 336-49, 2011.
C. D. Doucette, Schwab, D. J., Wingreen, N. S., and Rabinowitz, J. D., α-Ketoglutarate coordinates carbon and nitrogen utilization via enzyme I inhibition., Nat Chem Biol, vol. 7, no. 12, pp. 894-901, 2011.
2010
S. Goyal, Yuan, J., Chen, T., Rabinowitz, J. D., and Wingreen, N. S., Achieving optimal growth through product feedback inhibition in metabolism., PLoS Comput Biol, vol. 6, no. 6, p. e1000802, 2010.
S. Wang, Arellano-Santoyo, H., Combs, P. A., and Shaevitz, J. W., Actin-like cytoskeleton filaments contribute to cell mechanics in bacteria., Proc Natl Acad Sci U S A, vol. 107, no. 20, pp. 9182-5, 2010.
D. Gresham, Usaite, R., Germann, S. Manuela, Lisby, M., Botstein, D., and Regenberg, B., Adaptation to diverse nitrogen-limited environments by deletion or extrachromosomal element formation of the GAP1 locus., Proc Natl Acad Sci U S A, vol. 107, no. 43, pp. 18551-6, 2010.
C. T. Murphy, Aging: miRacles of longevity?, Curr Biol, vol. 20, no. 24, pp. R1076-8, 2010.
Y. Kyung Kwon, Higgins, M. B., and Rabinowitz, J. D., Antifolate-induced depletion of intracellular glycine and purines inhibits thymineless death in E. coli., ACS Chem Biol, vol. 5, no. 8, pp. 787-95, 2010.
P. Mehta and Gregor, T., Approaching the molecular origins of collective dynamics in oscillating cell populations., Curr Opin Genet Dev, vol. 20, no. 6, pp. 574-80, 2010.
J. D. Rabinowitz and White, E., Autophagy and metabolism., Science, vol. 330, no. 6009, pp. 1344-8, 2010.
O. Grimm and Wieschaus, E., The Bicoid gradient is shaped independently of nuclei., Development, vol. 137, no. 17, pp. 2857-62, 2010.
L. Christiaen, Stolfi, A., and Levine, M., BMP signaling coordinates gene expression and cell migration during precardiac mesoderm development., Dev Biol, vol. 340, no. 2, pp. 179-87, 2010.
K. L. Olszewski, Mather, M. W., Morrisey, J. M., Garcia, B. A., Vaidya, A. B., Rabinowitz, J. D., and Llinás, M., Branched tricarboxylic acid metabolism in Plasmodium falciparum., Nature, vol. 466, no. 7307, pp. 774-8, 2010.
X. Lu, Drocco, J., and Wieschaus, E. F., Cell cycle regulation via inter-nuclear communication during the early embryonic development of Drosophila melanogaster., Cell Cycle, vol. 9, no. 14, pp. 2908-10, 2010.
M. E. Kavousanakis, Kanodia, J. S., Kim, Y., Kevrekidis, I. G., and Shvartsman, S. Y., A compartmental model for the bicoid gradient., Dev Biol, vol. 345, no. 1, pp. 12-7, 2010.
S. Neumann, Hansen, C. H., Wingreen, N. S., and Sourjik, V., Differences in signalling by directly and indirectly binding ligands in bacterial chemotaxis., EMBO J, vol. 29, no. 20, pp. 3484-95, 2010.
C. H. Hansen, Sourjik, V., and Wingreen, N. S., A dynamic-signaling-team model for chemotaxis receptors in Escherichia coli., Proc Natl Acad Sci U S A, vol. 107, no. 40, pp. 17170-5, 2010.
A. Stolfi, T Gainous, B., Young, J. J., Mori, A., Levine, M., and Christiaen, L., Early chordate origins of the vertebrate second heart field., Science, vol. 329, no. 5991, pp. 565-8, 2010.
M. Wyart, Botstein, D., and Wingreen, N. S., Evaluating gene expression dynamics using pairwise RNA FISH data., PLoS Comput Biol, vol. 6, no. 11, p. e1000979, 2010.
G. J. Stephens, Johnson-Kerner, B., Bialek, W., and Ryu, W. S., From modes to movement in the behavior of Caenorhabditis elegans., PLoS One, vol. 5, no. 11, p. e13914, 2010.
Y. Guan, Ackert-Bicknell, C. L., Kell, B., Troyanskaya, O. G., and Hibbs, M. A., Functional genomics complements quantitative genetics in identifying disease-gene associations., PLoS Comput Biol, vol. 6, no. 11, p. e1000991, 2010.
The Gene Ontology in 2010: extensions and refinements., Nucleic Acids Res, vol. 38, no. Database issue, pp. D331-5, 2010.
M. Costanzo, Baryshnikova, A., Bellay, J., Kim, Y., Spear, E. D., Sevier, C. S., Ding, H., L Y Koh, J., Toufighi, K., Mostafavi, S., Prinz, J., St Onge, R. P., VanderSluis, B., Makhnevych, T., Vizeacoumar, F. J., Alizadeh, S., Bahr, S., Brost, R. L., Chen, Y., Cokol, M., Deshpande, R., Li, Z., Lin, Z. - Y., Liang, W., Marback, M., Paw, J., San Luis, B. - J., Shuteriqi, E., Tong, A. Hin Yan, van Dyk, N., Wallace, I. M., Whitney, J. A., Weirauch, M. T., Zhong, G., Zhu, H., Houry, W. A., Brudno, M., Ragibizadeh, S., Papp, B., Pál, C., Roth, F. P., Giaever, G., Nislow, C., Troyanskaya, O. G., Bussey, H., Bader, G. D., Gingras, A. - C., Morris, Q. D., Kim, P. M., Kaiser, C. A., Myers, C. L., Andrews, B. J., and Boone, C., The genetic landscape of a cell., Science, vol. 327, no. 5964, pp. 425-31, 2010.
J. A. Capra, Paeschke, K., Singh, M., and Zakian, V. A., G-quadruplex DNA sequences are evolutionarily conserved and associated with distinct genomic features in Saccharomyces cerevisiae., PLoS Comput Biol, vol. 6, no. 7, p. e1000861, 2010.
V. M. Boer, Crutchfield, C. A., Bradley, P. H., Botstein, D., and Rabinowitz, J. D., Growth-limiting intracellular metabolites in yeast growing under diverse nutrient limitations., Mol Biol Cell, vol. 21, no. 1, pp. 198-211, 2010.
P. L. Nara, Tobin, G. J., A Chaudhuri, R., Trujillo, J. D., Lin, G., Cho, M. W., Levin, S. A., Ndifon, W., and Wingreen, N. S., How can vaccines against influenza and other viral diseases be made more effective?, PLoS Biol, vol. 8, no. 12, p. e1000571, 2010.
A. M. Berezhkovskii, Sample, C., and Shvartsman, S. Y., How long does it take to establish a morphogen gradient?, Biophys J, vol. 99, no. 8, pp. L59-61, 2010.
B. M. Zee, Levin, R. S., Xu, B., LeRoy, G., Wingreen, N. S., and Garcia, B. A., In vivo residue-specific histone methylation dynamics., J Biol Chem, vol. 285, no. 5, pp. 3341-50, 2010.
S. D. Kocher, Ayroles, J. F., Stone, E. A., and Grozinger, C. M., Individual variation in pheromone response correlates with reproductive traits and brain gene expression in worker honey bees., PLoS One, vol. 5, no. 2, p. e9116, 2010.
A. L. Kauffman, Ashraf, J. M., M Corces-Zimmerman, R., Landis, J. N., and Murphy, C. T., Insulin signaling and dietary restriction differentially influence the decline of learning and memory with age., PLoS Biol, vol. 8, no. 5, p. e1000372, 2010.
A. Pop, Huttenhower, C., Iyer-Pascuzzi, A., Benfey, P. N., and Troyanskaya, O. G., Integrated functional networks of process, tissue, and developmental stage specific interactions in Arabidopsis thaliana., BMC Syst Biol, vol. 4, p. 180, 2010.
A. C. Martin, Gelbart, M., Fernandez-Gonzalez, R., Kaschube, M., and Wieschaus, E. F., Integration of contractile forces during tissue invagination., J Cell Biol, vol. 188, no. 5, pp. 735-49, 2010.
J. N. Landis and Murphy, C. T., Integration of diverse inputs in the regulation of Caenorhabditis elegans DAF-16/FOXO., Dev Dyn, vol. 239, no. 5, pp. 1405-12, 2010.
C. S. Greene and Troyanskaya, O. G., Integrative systems biology for data-driven knowledge discovery., Semin Nephrol, vol. 30, no. 5, pp. 443-54, 2010.
S. M. Tilghman, It's all about the talent., Mol Biol Cell, vol. 21, no. 22, p. 3823, 2010.
D. Botstein, It's the data!, Mol Biol Cell, vol. 21, no. 1, pp. 4-6, 2010.
T. Mora and Wingreen, N. S., Limits of sensing temporal concentration changes by single cells., Phys Rev Lett, vol. 104, no. 24, p. 248101, 2010.
Y. Kim, Coppey, M., Grossman, R., Ajuria, L., Jiménez, G., Paroush, Z. 'ev, and Shvartsman, S. Y., MAPK substrate competition integrates patterning signals in the Drosophila embryo., Curr Biol, vol. 20, no. 5, pp. 446-51, 2010.
F. Markowetz, Mulder, K. W., Airoldi, E. M., Lemischka, I. R., and Troyanskaya, O. G., Mapping dynamic histone acetylation patterns to gene expression in nanog-depleted murine embryonic stem cells., PLoS Comput Biol, vol. 6, no. 12, p. e1001034, 2010.
C. A. Crutchfield, Lu, W., Melamud, E., and Rabinowitz, J. D., Mass spectrometry-based metabolomics of yeast., Methods Enzymol, vol. 470, pp. 393-426, 2010.
T. Mora, Walczak, A. M., Bialek, W., and Callan, C. G., Maximum entropy models for antibody diversity., Proc Natl Acad Sci U S A, vol. 107, no. 12, pp. 5405-10, 2010.
S. - W. Teng, Wang, Y., Tu, K. C., Long, T., Mehta, P., Wingreen, N. S., Bassler, B. L., and Ong, N. P., Measurement of the copy number of the master quorum-sensing regulator of a bacterial cell., Biophys J, vol. 98, no. 9, pp. 2024-31, 2010.
S. Wang, Arellano-Santoyo, H., Combs, P. A., and Shaevitz, J. W., Measuring the bending stiffness of bacterial cells using an optical trap., J Vis Exp, no. 38, 2010.
S. J. Silverman, Petti, A. A., Slavov, N., Parsons, L., Briehof, R., Thiberge, S. Y., Zenklusen, D., Gandhi, S. J., Larson, D. R., Singer, R. H., and Botstein, D., Metabolic cycling in single yeast cells from unsynchronized steady-state populations limited on glucose or phosphate., Proc Natl Acad Sci U S A, vol. 107, no. 15, pp. 6946-51, 2010.
E. Melamud, Vastag, L., and Rabinowitz, J. D., Metabolomic analysis and visualization engine for LC-MS data., Anal Chem, vol. 82, no. 23, pp. 9818-26, 2010.
W. Lu, Clasquin, M. F., Melamud, E., Amador-Noguez, D., Caudy, A. A., and Rabinowitz, J. D., Metabolomic analysis via reversed-phase ion-pairing liquid chromatography coupled to a stand alone orbitrap mass spectrometer., Anal Chem, vol. 82, no. 8, pp. 3212-21, 2010.
D. Hendrix, Levine, M., and Shi, W., miRTRAP, a computational method for the systematic identification of miRNAs from high throughput sequencing data., Genome Biol, vol. 11, no. 4, p. R39, 2010.
P. B. Kidd and Wingreen, N. S., Modeling the role of covalent enzyme modification in Escherichia coli nitrogen metabolism., Phys Biol, vol. 7, no. 1, p. 016006, 2010.
O. Grimm, Coppey, M., and Wieschaus, E., Modelling the Bicoid gradient., Development, vol. 137, no. 14, pp. 2253-64, 2010.
J. P. Bothma, Levine, M., and Boettiger, A., Morphogen gradients: limits to signaling or limits to measurement?, Curr Biol, vol. 20, no. 5, pp. R232-4, 2010.
C. Sample and Shvartsman, S. Y., Multiscale modeling of diffusion in the early Drosophila embryo., Proc Natl Acad Sci U S A, vol. 107, no. 22, pp. 10092-6, 2010.
K. C. Tu, Long, T., Svenningsen, S. L., Wingreen, N. S., and Bassler, B. L., Negative feedback loops involving small regulatory RNAs precisely control the Vibrio harveyi quorum-sensing response., Mol Cell, vol. 37, no. 4, pp. 567-79, 2010.
T. Gregor, Fujimoto, K., Masaki, N., and Sawai, S., The onset of collective behavior in social amoebae., Science, vol. 328, no. 5981, pp. 1021-5, 2010.
D. Gresham, Curry, B., Ward, A., D Gordon, B., Brizuela, L., Kruglyak, L., and Botstein, D., Optimized detection of sequence variation in heterozygous genomes using DNA microarrays with isothermal-melting probes., Proc Natl Acad Sci U S A, vol. 107, no. 4, pp. 1482-7, 2010.
A. M. Walczak, Tkačik, G., and Bialek, W., Optimizing information flow in small genetic networks. II. Feed-forward interactions., Phys Rev E Stat Nonlin Soft Matter Phys, vol. 81, no. 4 Pt 1, p. 041905, 2010.
Y. Meir, Jakovljevic, V., Oleksiuk, O., Sourjik, V., and Wingreen, N. S., Precision and kinetics of adaptation in bacterial chemotaxis., Biophys J, vol. 99, no. 9, pp. 2766-74, 2010.
W. - L. Ng, Wei, Y., Perez, L. J., Cong, J., Long, T., Koch, M., Semmelhack, M. F., Wingreen, N. S., and Bassler, B. L., Probing bacterial transmembrane histidine kinase receptor-ligand interactions with natural and synthetic molecules., Proc Natl Acad Sci U S A, vol. 107, no. 12, pp. 5575-80, 2010.
A. Baryshnikova, Costanzo, M., Kim, Y., Ding, H., Koh, J., Toufighi, K., Youn, J. - Y., Ou, J., San Luis, B. - J., Bandyopadhyay, S., Hibbs, M., Hess, D., Gingras, A. - C., Bader, G. D., Troyanskaya, O. G., Brown, G. W., Andrews, B., Boone, C., and Myers, C. L., Quantitative analysis of fitness and genetic interactions in yeast on a genome scale., Nat Methods, vol. 7, no. 12, pp. 1017-24, 2010.
J. M. S. Lemons, Feng, X. - J., Bennett, B. D., Legesse-Miller, A., Johnson, E. L., Raitman, I., Pollina, E. A., Rabitz, H. A., Rabinowitz, J. D., and Coller, H. A., Quiescent fibroblasts exhibit high metabolic activity., PLoS Biol, vol. 8, no. 10, p. e1000514, 2010.
H. Goodarzi, Bennett, B. D., Amini, S., Reaves, M. L., Hottes, A. K., Rabinowitz, J. D., and Tavazoie, S., Regulatory and metabolic rewiring during laboratory evolution of ethanol tolerance in E. coli., Mol Syst Biol, vol. 6, p. 378, 2010.
R. Kaletsky and Murphy, C. T., The role of insulin/IGF-like signaling in C. elegans longevity and aging., Dis Model Mech, vol. 3, no. 7-8, pp. 415-9, 2010.
S. R. Engel, Balakrishnan, R., Binkley, G., Christie, K. R., Costanzo, M. C., Dwight, S. S., Fisk, D. G., Hirschman, J. E., Hitz, B. C., Hong, E. L., Krieger, C. J., Livstone, M. S., Miyasato, S. R., Nash, R., Oughtred, R., Park, J., Skrzypek, M. S., Weng, S., Wong, E. D., Dolinski, K., Botstein, D., and J Cherry, M., Saccharomyces Genome Database provides mutant phenotype data., Nucleic Acids Res, vol. 38, no. Database issue, pp. D433-6, 2010.
M. W. Perry, Boettiger, A. N., Bothma, J. P., and Levine, M., Shadow enhancers foster robustness of Drosophila gastrulation., Curr Biol, vol. 20, no. 17, pp. 1562-7, 2010.
C. Y. Park, Hess, D. C., Huttenhower, C., and Troyanskaya, O. G., Simultaneous genome-wide inference of physical, genetic, regulatory, and functional pathway components., PLoS Comput Biol, vol. 6, no. 11, p. e1001009, 2010.
P. Jiang and Singh, M., SPICi: a fast clustering algorithm for large biological networks., Bioinformatics, vol. 26, no. 8, pp. 1105-11, 2010.
G. J. Stephens and Bialek, W., Statistical mechanics of letters in words., Phys Rev E Stat Nonlin Soft Matter Phys, vol. 81, no. 6 Pt 2, p. 066119, 2010.
J. W. Shaevitz and Gitai, Z., The structure and function of bacterial actin homologs., Cold Spring Harb Perspect Biol, vol. 2, no. 9, p. a000364, 2010.
Y. Guan, Dunham, M., Caudy, A., and Troyanskaya, O., Systematic planning of genome-scale experiments in poorly studied species., PLoS Comput Biol, vol. 6, no. 3, p. e1000698, 2010.
P. Jumbo-Lucioni, Ayroles, J. F., Chambers, M. Moses, Jordan, K. W., Leips, J., Mackay, T. Fc, and De Luca, M., Systems genetics analysis of body weight and energy metabolism traits in Drosophila melanogaster., BMC Genomics, vol. 11, p. 297, 2010.
D. Amador-Noguez, Feng, X. - J., Fan, J., Roquet, N., Rabitz, H., and Rabinowitz, J. D., Systems-level metabolic flux profiling elucidates a complete, bifurcated tricarboxylic acid cycle in Clostridium acetobutylicum., J Bacteriol, vol. 192, no. 17, pp. 4452-61, 2010.
D. Botstein, Technological innovation leads to fundamental understanding in cell biology., Mol Biol Cell, vol. 21, no. 22, pp. 3791-2, 2010.
A. C. Martin and Wieschaus, E. F., Tensions divide., Nat Cell Biol, vol. 12, no. 1, pp. 5-7, 2010.
S. Luo, Kleemann, G. A., Ashraf, J. M., Shaw, W. M., and Murphy, C. T., TGF-β and insulin signaling regulate reproductive aging via oocyte and germline quality maintenance., Cell, vol. 143, no. 2, pp. 299-312, 2010.
J. J. Zartman and Shvartsman, S. Y., Unit operations of tissue development: epithelial folding., Annu Rev Chem Biomol Eng, vol. 1, pp. 231-46, 2010.
J. Parsch, Novozhilov, S., Saminadin-Peter, S. S., Wong, K. M., and Andolfatto, P., On the utility of short intron sequences as a reference for the detection of positive and negative selection in Drosophila., Mol Biol Evol, vol. 27, no. 6, pp. 1226-34, 2010.
B. Haley, Foys, B., and Levine, M., Vectors and parameters that enhance the efficacy of RNAi-mediated gene disruption in transgenic Drosophila., Proc Natl Acad Sci U S A, vol. 107, no. 25, pp. 11435-40, 2010.
M. Tipping, Kim, Y., Kyriakakis, P., Tong, M., Shvartsman, S. Y., and Veraksa, A., β-arrestin Kurtz inhibits MAPK and Toll signalling in Drosophila development., EMBO J, vol. 29, no. 19, pp. 3222-35, 2010.
2009
B. D. Bennett, Kimball, E. H., Gao, M., Osterhout, R., Van Dien, S. J., and Rabinowitz, J. D., Absolute metabolite concentrations and implied enzyme active site occupancy in Escherichia coli., Nat Chem Biol, vol. 5, no. 8, pp. 593-9, 2009.
R. G. Endres and Wingreen, N. S., Accuracy of direct gradient sensing by cell-surface receptors., Prog Biophys Mol Biol, vol. 100, no. 1-3, pp. 33-9, 2009.
T. V. Morozova, Ayroles, J. F., Jordan, K. W., Duncan, L. H., Carbone, M. Anna, Lyman, R. F., Stone, E. A., Govindaraju, D. R., R Ellison, C., Mackay, T. F. C., and Anholt, R. R. H., Alcohol sensitivity in Drosophila: translational potential of systems genetics., Genetics, vol. 183, no. 2, pp. 733-45, 1SI-12SI, 2009.
Z. Barutcuoglu, Airoldi, E. M., Dumeaux, V., Schapire, R. E., and Troyanskaya, O. G., Aneuploidy prediction and tumor classification with heterogeneous hidden conditional random fields., Bioinformatics, vol. 25, no. 10, pp. 1307-13, 2009.
S. - J. Yan, Zartman, J. J., Zhang, M., Scott, A., Shvartsman, S. Y., and Li, W. X., Bistability coordinates activation of the EGFR and DPP pathways in Drosophila vein differentiation., Mol Syst Biol, vol. 5, p. 278, 2009.
C. Huttenhower, Myers, C. L., Hibbs, M. A., and Troyanskaya, O. G., Computational analysis of the yeast proteome: understanding and exploiting functional specificity in genomic data., Methods Mol Biol, vol. 548, pp. 273-93, 2009.
D. C. Hess, Myers, C. L., Huttenhower, C., Hibbs, M. A., Hayes, A. P., Paw, J., Clore, J. J., Mendoza, R. M., San Luis, B., Nislow, C., Giaever, G., Costanzo, M., Troyanskaya, O. G., and Caudy, A. A., Computationally driven, quantitative experiments discover genes required for mitochondrial biogenesis., PLoS Genet, vol. 5, no. 3, p. e1000407, 2009.
R. P. Oliveira, Abate, J. Porter, Dilks, K., Landis, J., Ashraf, J., Murphy, C. T., and T Blackwell, K., Condition-adapted stress and longevity gene regulation by Caenorhabditis elegans SKN-1/Nrf., Aging Cell, vol. 8, no. 5, pp. 524-41, 2009.
J. Cande, Goltsev, Y., and Levine, M. S., Conservation of enhancer location in divergent insects., Proc Natl Acad Sci U S A, vol. 106, no. 34, pp. 14414-9, 2009.
P. H. Bradley, Brauer, M. J., Rabinowitz, J. D., and Troyanskaya, O. G., Coordinated concentration changes of transcripts and metabolites in Saccharomyces cerevisiae., PLoS Comput Biol, vol. 5, no. 1, p. e1000270, 2009.
S. T. Harbison, Carbone, M. Anna, Ayroles, J. F., Stone, E. A., Lyman, R. F., and Mackay, T. F. C., Co-regulated transcriptional networks contribute to natural genetic variation in Drosophila sleep., Nat Genet, vol. 41, no. 3, pp. 371-5, 2009.
G. I. Lang, Murray, A. W., and Botstein, D., The cost of gene expression underlies a fitness trade-off in yeast., Proc Natl Acad Sci U S A, vol. 106, no. 14, pp. 5755-60, 2009.
X. Lu, Li, J. M., Elemento, O., Tavazoie, S., and Wieschaus, E. F., Coupling of zygotic transcription to mitotic control at the Drosophila mid-blastula transition., Development, vol. 136, no. 12, pp. 2101-10, 2009.
R. Mukhopadhyay and Wingreen, N. S., Curvature and shape determination of growing bacteria., Phys Rev E Stat Nonlin Soft Matter Phys, vol. 80, no. 6 Pt 1, p. 062901, 2009.
C. Huttenhower, K Mutungu, T., Indik, N., Yang, W., Schroeder, M., Forman, J. J., Troyanskaya, O. G., and Coller, H. A., Detailing regulatory networks through large scale data integration., Bioinformatics, vol. 25, no. 24, pp. 3267-74, 2009.
Y. Goltsev, Rezende, G. L., Vranizan, K., Lanzaro, G., Valle, D., and Levine, M., Developmental and evolutionary basis for drought tolerance of the Anopheles gambiae embryo., Dev Biol, vol. 330, no. 2, pp. 462-70, 2009.
W. Ndifon, Wingreen, N. S., and Levin, S. A., Differential neutralization efficiency of hemagglutinin epitopes, antibody interference, and the design of influenza vaccines., Proc Natl Acad Sci U S A, vol. 106, no. 21, pp. 8701-6, 2009.
G. Tkačik and Bialek, W., Diffusion, dimensionality, and noise in transcriptional regulation., Phys Rev E Stat Nonlin Soft Matter Phys, vol. 79, no. 5 Pt 1, p. 051901, 2009.
M. A. Hibbs, Myers, C. L., Huttenhower, C., Hess, D. C., Li, K., Caudy, A. A., and Troyanskaya, O. G., Directing experimental biology: a case study in mitochondrial biogenesis., PLoS Comput Biol, vol. 5, no. 3, p. e1000322, 2009.
C. L. Myers, Chiriac, C., and Troyanskaya, O. G., Discovering biological networks from diverse functional genomic data., Methods Mol Biol, vol. 563, pp. 157-75, 2009.
J. S. Kanodia, Rikhy, R., Kim, Y., Lund, V. K., DeLotto, R., Lippincott-Schwartz, J., and Shvartsman, S. Y., Dynamics of the Dorsal morphogen gradient., Proc Natl Acad Sci U S A, vol. 106, no. 51, pp. 21707-12, 2009.
Y. Deng and Shaevitz, J. W., Effect of aberration on height calibration in three-dimensional localization-based microscopy and particle tracking., Appl Opt, vol. 48, no. 10, pp. 1886-90, 2009.
L. Christiaen, Wagner, E., Shi, W., and Levine, M., Electroporation of transgenic DNAs in the sea squirt Ciona., Cold Spring Harb Protoc, vol. 2009, no. 12, p. pdb.prot5345, 2009.
M. Rebeiz, Ramos-Womack, M., Jeong, S., Andolfatto, P., Werner, T., True, J., Stern, D. L., and Carroll, S. B., Evolution of the tan locus contributed to pigment loss in Drosophila santomea: a response to Matute et al., Cell, vol. 139, no. 6, pp. 1189-96, 2009.
J. Doran Cande, Chopra, V. S., and Levine, M., Evolving enhancer-promoter interactions within the tinman complex of the flour beetle, Tribolium castaneum., Development, vol. 136, no. 18, pp. 3153-60, 2009.
C. Huttenhower, Haley, E. M., Hibbs, M. A., Dumeaux, V., Barrett, D. R., Coller, H. A., and Troyanskaya, O. G., Exploring the human genome with functional maps., Genome Res, vol. 19, no. 6, pp. 1093-106, 2009.
J. J. Zartman, Kanodia, J. S., Yakoby, N., Schafer, X., Watson, C., Schlichting, K., Dahmann, C., and Shvartsman, S. Y., Expression patterns of cadherin genes in Drosophila oogenesis., Gene Expr Patterns, vol. 9, no. 1, pp. 31-6, 2009.
J. J. Zartman, Kanodia, J. S., Cheung, L. S., and Shvartsman, S. Y., Feedback control of the EGFR signaling gradient: superposition of domain-splitting events in Drosophila oogenesis., Development, vol. 136, no. 17, pp. 2903-11, 2009.
W. Shi, Peyrot, S. M., Munro, E., and Levine, M., FGF3 in the floor plate directs notochord convergent extension in the Ciona tadpole., Development, vol. 136, no. 1, pp. 23-8, 2009.
T. F. C. Mackay, Stone, E. A., and Ayroles, J. F., The genetics of quantitative traits: challenges and prospects., Nat Rev Genet, vol. 10, no. 8, pp. 565-77, 2009.
J. F. Ayroles, Hughes, K. A., Rowe, K. C., Reedy, M. M., Rodriguez-Zas, S. L., Drnevich, J. M., Cáceres, C. E., and Paige, K. N., A genomewide assessment of inbreeding depression: gene number, function, and mode of action., Conserv Biol, vol. 23, no. 4, pp. 920-30, 2009.
M. D. Chikina, Huttenhower, C., Murphy, C. T., and Troyanskaya, O. G., Global prediction of tissue-specific gene expression and context-dependent gene networks in Caenorhabditis elegans., PLoS Comput Biol, vol. 5, no. 6, p. e1000417, 2009.
S. - J. Lee, Murphy, C. T., and Kenyon, C., Glucose shortens the life span of C. elegans by downregulating DAF-16/FOXO activity and aquaporin gene expression., Cell Metab, vol. 10, no. 5, pp. 379-91, 2009.
C. Huttenhower, Mehmood, S. O., and Troyanskaya, O. G., Graphle: Interactive exploration of large, dense graphs., BMC Bioinformatics, vol. 10, p. 417, 2009.
K. L. Olszewski, Morrisey, J. M., Wilinski, D., Burns, J. M., Vaidya, A. B., Rabinowitz, J. D., and Llinás, M., Host-parasite interactions revealed by Plasmodium falciparum metabolomics., Cell Host Microbe, vol. 5, no. 2, pp. 191-9, 2009.
J. Song and Singh, M., How and when should interactome-derived clusters be used to predict functional modules and protein function?, Bioinformatics, vol. 25, no. 23, pp. 3143-50, 2009.
C. Huttenhower, Hibbs, M. A., Myers, C. L., Caudy, A. A., Hess, D. C., and Troyanskaya, O. G., The impact of incomplete knowledge on evaluation: an experimental benchmark for protein function prediction., Bioinformatics, vol. 25, no. 18, pp. 2404-10, 2009.
P. Mehta, Goyal, S., Long, T., Bassler, B. L., and Wingreen, N. S., Information processing and signal integration in bacterial quorum sensing., Mol Syst Biol, vol. 5, p. 325, 2009.
L. Christiaen, Wagner, E., Shi, W., and Levine, M., Isolation of individual cells and tissues from electroporated sea squirt (Ciona) embryos by fluorescence-activated cell sorting (FACS)., Cold Spring Harb Protoc, vol. 2009, no. 12, p. pdb.prot5349, 2009.
L. Christiaen, Wagner, E., Shi, W., and Levine, M., Isolation of sea squirt (Ciona) gametes, fertilization, dechorionation, and development., Cold Spring Harb Protoc, vol. 2009, no. 12, p. pdb.prot5344, 2009.
S. Y. Shvartsman, Coppey, M., and Berezhkovskii, A. M., MAPK signaling in equations and embryos., Fly (Austin), vol. 3, no. 1, pp. 62-7, 2009.
R. G. Endres and Wingreen, N. S., Maximum likelihood and the single receptor., Phys Rev Lett, vol. 103, no. 15, p. 158101, 2009.
J. S. Bloom, Khan, Z., Kruglyak, L., Singh, M., and Caudy, A. A., Measuring differential gene expression by short read sequencing: quantitative comparison to 2-channel gene expression microarrays., BMC Genomics, vol. 10, p. 221, 2009.
J. Yuan, Doucette, C. D., Fowler, W. U., Feng, X. - J., Piazza, M., Rabitz, H. A., Wingreen, N. S., and Rabinowitz, J. D., Metabolomics-driven quantitative analysis of ammonia assimilation in E. coli., Mol Syst Biol, vol. 5, p. 302, 2009.
L. Christiaen, Wagner, E., Shi, W., and Levine, M., Microinjection of morpholino oligos and RNAs in sea squirt (Ciona) embryos., Cold Spring Harb Protoc, vol. 2009, no. 12, p. pdb.prot5347, 2009.
T. Mora, Yu, H., and Wingreen, N. S., Modeling torque versus speed, shot noise, and rotational diffusion of the bacterial flagellar motor., Phys Rev Lett, vol. 103, no. 24, p. 248102, 2009.
E. A. Stone and Ayroles, J. F., Modulated modularity clustering as an exploratory tool for functional genomic inference., PLoS Genet, vol. 5, no. 5, p. e1000479, 2009.
C. Hei Ho, Magtanong, L., Barker, S. L., Gresham, D., Nishimura, S., Natarajan, P., L Y Koh, J., Porter, J., Gray, C. A., Andersen, R. J., Giaever, G., Nislow, C., Andrews, B., Botstein, D., Graham, T. R., Yoshida, M., and Boone, C., A molecular barcoded yeast ORF library enables mode-of-action analysis of bioactive compounds., Nat Biotechnol, vol. 27, no. 4, pp. 369-77, 2009.
G. Tkačik, Walczak, A. M., and Bialek, W., Optimizing information flow in small genetic networks., Phys Rev E Stat Nonlin Soft Matter Phys, vol. 80, no. 3 Pt 1, p. 031920, 2009.
D. Papatsenko, Goltsev, Y., and Levine, M., Organization of developmental enhancers in the Drosophila embryo., Nucleic Acids Res, vol. 37, no. 17, pp. 5665-77, 2009.

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