Wounds and Injuries
H. Y. Chang, Sneddon, J. B., Alizadeh, A. A., Sood, R., West, R. B., Montgomery, K., Chi, J. - T., van de Rijn, M., Botstein, D., and Brown, P. O.,
“Gene expression signature of fibroblast serum response predicts human cancer progression: similarities between tumors and wounds.”,
PLoS Biol, vol. 2, no. 2, p. E7, 2004.
Tumor Markers, Biological
J. Lapointe, Li, C., Higgins, J. P., van de Rijn, M., Bair, E., Montgomery, K., Ferrari, M., Egevad, L., Rayford, W., Bergerheim, U., Ekman, P., DeMarzo, A. M., Tibshirani, R., Botstein, D., Brown, P. O., Brooks, J. D., and Pollack, J. R.,
“Gene expression profiling identifies clinically relevant subtypes of prostate cancer.”,
Proc Natl Acad Sci U S A, vol. 101, no. 3, pp. 811-6, 2004.
M. van de Rijn, Perou, C. M., Tibshirani, R., Haas, P., Kallioniemi, O., Kononen, J., Torhorst, J., Sauter, G., Zuber, M., Köchli, O. R., Mross, F., Dieterich, H., Seitz, R., Ross, D., Botstein, D., and Brown, P.,
“Expression of cytokeratins 17 and 5 identifies a group of breast carcinomas with poor clinical outcome.”,
Am J Pathol, vol. 161, no. 6, pp. 1991-6, 2002.
Tumor Cells, Cultured
M. E. Schaner, Ross, D. T., Ciaravino, G., Sorlie, T., Troyanskaya, O., Diehn, M., Wang, Y. C., Duran, G. E., Sikic, T. L., Caldeira, S., Skomedal, H., Tu, I. - P., Hernandez-Boussard, T., Johnson, S. W., O'Dwyer, P. J., Fero, M. J., Kristensen, G. B., Borresen-Dale, A. - L., Hastie, T., Tibshirani, R., van de Rijn, M., Teng, N. N., Longacre, T. A., Botstein, D., Brown, P. O., and Sikic, B. I.,
“Gene expression patterns in ovarian carcinomas.”,
Mol Biol Cell, vol. 14, no. 11, pp. 4376-86, 2003.
Treatment Outcome
M. van de Rijn, Perou, C. M., Tibshirani, R., Haas, P., Kallioniemi, O., Kononen, J., Torhorst, J., Sauter, G., Zuber, M., Köchli, O. R., Mross, F., Dieterich, H., Seitz, R., Ross, D., Botstein, D., and Brown, P.,
“Expression of cytokeratins 17 and 5 identifies a group of breast carcinomas with poor clinical outcome.”,
Am J Pathol, vol. 161, no. 6, pp. 1991-6, 2002.
Transcription Factors
T. O. Nielsen, Hsu, F. D., O'Connell, J. X., C Gilks, B., Sorensen, P. H. B., Linn, S., West, R. B., Liu, C. Long, Botstein, D., Brown, P. O., and van de Rijn, M.,
“Tissue microarray validation of epidermal growth factor receptor and SALL2 in synovial sarcoma with comparison to tumors of similar histology.”,
Am J Pathol, vol. 163, no. 4, pp. 1449-56, 2003.
M. E. Schaner, Ross, D. T., Ciaravino, G., Sorlie, T., Troyanskaya, O., Diehn, M., Wang, Y. C., Duran, G. E., Sikic, T. L., Caldeira, S., Skomedal, H., Tu, I. - P., Hernandez-Boussard, T., Johnson, S. W., O'Dwyer, P. J., Fero, M. J., Kristensen, G. B., Borresen-Dale, A. - L., Hastie, T., Tibshirani, R., van de Rijn, M., Teng, N. N., Longacre, T. A., Botstein, D., Brown, P. O., and Sikic, B. I.,
“Gene expression patterns in ovarian carcinomas.”,
Mol Biol Cell, vol. 14, no. 11, pp. 4376-86, 2003.
J. - T. Chi, Chang, H. Y., Haraldsen, G., Jahnsen, F. L., Troyanskaya, O. G., Chang, D. S., Wang, Z., Rockson, S. G., van de Rijn, M., Botstein, D., and Brown, P. O.,
“Endothelial cell diversity revealed by global expression profiling.”,
Proc Natl Acad Sci U S A, vol. 100, no. 19, pp. 10623-8, 2003.
Trans-Activators
M. E. Schaner, Ross, D. T., Ciaravino, G., Sorlie, T., Troyanskaya, O., Diehn, M., Wang, Y. C., Duran, G. E., Sikic, T. L., Caldeira, S., Skomedal, H., Tu, I. - P., Hernandez-Boussard, T., Johnson, S. W., O'Dwyer, P. J., Fero, M. J., Kristensen, G. B., Borresen-Dale, A. - L., Hastie, T., Tibshirani, R., van de Rijn, M., Teng, N. N., Longacre, T. A., Botstein, D., Brown, P. O., and Sikic, B. I.,
“Gene expression patterns in ovarian carcinomas.”,
Mol Biol Cell, vol. 14, no. 11, pp. 4376-86, 2003.
Tissue Fixation
S. C. Linn, West, R. B., Pollack, J. R., Zhu, S., Hernandez-Boussard, T., Nielsen, T. O., Rubin, B. P., Patel, iv, R., Goldblum, J. R., Siegmund, D., Botstein, D., Brown, P. O., C Gilks, B., and van de Rijn, M.,
“Gene expression patterns and gene copy number changes in dermatofibrosarcoma protuberans.”,
Am J Pathol, vol. 163, no. 6, pp. 2383-95, 2003.
Tissue Distribution
R. Shyamsundar, Kim, Y. H., Higgins, J. P., Montgomery, K., Jorden, M., Sethuraman, A., van de Rijn, M., Botstein, D., Brown, P. O., and Pollack, J. R.,
“A DNA microarray survey of gene expression in normal human tissues.”,
Genome Biol, vol. 6, no. 3, p. R22, 2005.
Survival Rate
M. van de Rijn, Perou, C. M., Tibshirani, R., Haas, P., Kallioniemi, O., Kononen, J., Torhorst, J., Sauter, G., Zuber, M., Köchli, O. R., Mross, F., Dieterich, H., Seitz, R., Ross, D., Botstein, D., and Brown, P.,
“Expression of cytokeratins 17 and 5 identifies a group of breast carcinomas with poor clinical outcome.”,
Am J Pathol, vol. 161, no. 6, pp. 1991-6, 2002.
Staining and Labeling
T. O. Nielsen, Hsu, F. D., O'Connell, J. X., C Gilks, B., Sorensen, P. H. B., Linn, S., West, R. B., Liu, C. Long, Botstein, D., Brown, P. O., and van de Rijn, M.,
“Tissue microarray validation of epidermal growth factor receptor and SALL2 in synovial sarcoma with comparison to tumors of similar histology.”,
Am J Pathol, vol. 163, no. 4, pp. 1449-56, 2003.
Soft Tissue Neoplasms
T. O. Nielsen, Hsu, F. D., O'Connell, J. X., C Gilks, B., Sorensen, P. H. B., Linn, S., West, R. B., Liu, C. Long, Botstein, D., Brown, P. O., and van de Rijn, M.,
“Tissue microarray validation of epidermal growth factor receptor and SALL2 in synovial sarcoma with comparison to tumors of similar histology.”,
Am J Pathol, vol. 163, no. 4, pp. 1449-56, 2003.
T. O. Nielsen, West, R. B., Linn, S. C., Alter, O., Knowling, M. A., O'Connell, J. X., Zhu, S., Fero, M., Sherlock, G., Pollack, J. R., Brown, P. O., Botstein, D., and van de Rijn, M.,
“Molecular characterisation of soft tissue tumours: a gene expression study.”,
Lancet, vol. 359, no. 9314, pp. 1301-7, 2002.
Skin Neoplasms
S. C. Linn, West, R. B., Pollack, J. R., Zhu, S., Hernandez-Boussard, T., Nielsen, T. O., Rubin, B. P., Patel, iv, R., Goldblum, J. R., Siegmund, D., Botstein, D., Brown, P. O., C Gilks, B., and van de Rijn, M.,
“Gene expression patterns and gene copy number changes in dermatofibrosarcoma protuberans.”,
Am J Pathol, vol. 163, no. 6, pp. 2383-95, 2003.
Serum Response Element
H. Y. Chang, Sneddon, J. B., Alizadeh, A. A., Sood, R., West, R. B., Montgomery, K., Chi, J. - T., van de Rijn, M., Botstein, D., and Brown, P. O.,
“Gene expression signature of fibroblast serum response predicts human cancer progression: similarities between tumors and wounds.”,
PLoS Biol, vol. 2, no. 2, p. E7, 2004.
Seminal Plasma Proteins
J. Lapointe, Li, C., Higgins, J. P., van de Rijn, M., Bair, E., Montgomery, K., Ferrari, M., Egevad, L., Rayford, W., Bergerheim, U., Ekman, P., DeMarzo, A. M., Tibshirani, R., Botstein, D., Brown, P. O., Brooks, J. D., and Pollack, J. R.,
“Gene expression profiling identifies clinically relevant subtypes of prostate cancer.”,
Proc Natl Acad Sci U S A, vol. 101, no. 3, pp. 811-6, 2004.
Sarcoma, Synovial
T. O. Nielsen, Hsu, F. D., O'Connell, J. X., C Gilks, B., Sorensen, P. H. B., Linn, S., West, R. B., Liu, C. Long, Botstein, D., Brown, P. O., and van de Rijn, M.,
“Tissue microarray validation of epidermal growth factor receptor and SALL2 in synovial sarcoma with comparison to tumors of similar histology.”,
Am J Pathol, vol. 163, no. 4, pp. 1449-56, 2003.
Sarcoma
T. O. Nielsen, West, R. B., Linn, S. C., Alter, O., Knowling, M. A., O'Connell, J. X., Zhu, S., Fero, M., Sherlock, G., Pollack, J. R., Brown, P. O., Botstein, D., and van de Rijn, M.,
“Molecular characterisation of soft tissue tumours: a gene expression study.”,
Lancet, vol. 359, no. 9314, pp. 1301-7, 2002.
RNA, Neoplasm
X. Chen, Cheung, S. Tim, So, S., Fan, S. Tat, Barry, C., Higgins, J., Lai, K. - M., Ji, J., Dudoit, S., Ng, I. O. L., van de Rijn, M., Botstein, D., and Brown, P. O.,
“Gene expression patterns in human liver cancers.”,
Mol Biol Cell, vol. 13, no. 6, pp. 1929-39, 2002.
RNA, Messenger
H. Y. Chang, Chi, J. - T., Dudoit, S., Bondre, C., van de Rijn, M., Botstein, D., and Brown, P. O.,
“Diversity, topographic differentiation, and positional memory in human fibroblasts.”,
Proc Natl Acad Sci U S A, vol. 99, no. 20, pp. 12877-82, 2002.
R. Shyamsundar, Kim, Y. H., Higgins, J. P., Montgomery, K., Jorden, M., Sethuraman, A., van de Rijn, M., Botstein, D., Brown, P. O., and Pollack, J. R.,
“A DNA microarray survey of gene expression in normal human tissues.”,
Genome Biol, vol. 6, no. 3, p. R22, 2005.
Risk Factors
J. Lapointe, Li, C., Higgins, J. P., van de Rijn, M., Bair, E., Montgomery, K., Ferrari, M., Egevad, L., Rayford, W., Bergerheim, U., Ekman, P., DeMarzo, A. M., Tibshirani, R., Botstein, D., Brown, P. O., Brooks, J. D., and Pollack, J. R.,
“Gene expression profiling identifies clinically relevant subtypes of prostate cancer.”,
Proc Natl Acad Sci U S A, vol. 101, no. 3, pp. 811-6, 2004.
Recurrence
J. Lapointe, Li, C., Higgins, J. P., van de Rijn, M., Bair, E., Montgomery, K., Ferrari, M., Egevad, L., Rayford, W., Bergerheim, U., Ekman, P., DeMarzo, A. M., Tibshirani, R., Botstein, D., Brown, P. O., Brooks, J. D., and Pollack, J. R.,
“Gene expression profiling identifies clinically relevant subtypes of prostate cancer.”,
Proc Natl Acad Sci U S A, vol. 101, no. 3, pp. 811-6, 2004.
Receptors, Estrogen
M. E. Schaner, Ross, D. T., Ciaravino, G., Sorlie, T., Troyanskaya, O., Diehn, M., Wang, Y. C., Duran, G. E., Sikic, T. L., Caldeira, S., Skomedal, H., Tu, I. - P., Hernandez-Boussard, T., Johnson, S. W., O'Dwyer, P. J., Fero, M. J., Kristensen, G. B., Borresen-Dale, A. - L., Hastie, T., Tibshirani, R., van de Rijn, M., Teng, N. N., Longacre, T. A., Botstein, D., Brown, P. O., and Sikic, B. I.,
“Gene expression patterns in ovarian carcinomas.”,
Mol Biol Cell, vol. 14, no. 11, pp. 4376-86, 2003.
Receptor, Epidermal Growth Factor
T. O. Nielsen, Hsu, F. D., O'Connell, J. X., C Gilks, B., Sorensen, P. H. B., Linn, S., West, R. B., Liu, C. Long, Botstein, D., Brown, P. O., and van de Rijn, M.,
“Tissue microarray validation of epidermal growth factor receptor and SALL2 in synovial sarcoma with comparison to tumors of similar histology.”,
Am J Pathol, vol. 163, no. 4, pp. 1449-56, 2003.
Prostatic Neoplasms
J. Lapointe, Li, C., Higgins, J. P., van de Rijn, M., Bair, E., Montgomery, K., Ferrari, M., Egevad, L., Rayford, W., Bergerheim, U., Ekman, P., DeMarzo, A. M., Tibshirani, R., Botstein, D., Brown, P. O., Brooks, J. D., and Pollack, J. R.,
“Gene expression profiling identifies clinically relevant subtypes of prostate cancer.”,
Proc Natl Acad Sci U S A, vol. 101, no. 3, pp. 811-6, 2004.
Prognosis
J. Lapointe, Li, C., Higgins, J. P., van de Rijn, M., Bair, E., Montgomery, K., Ferrari, M., Egevad, L., Rayford, W., Bergerheim, U., Ekman, P., DeMarzo, A. M., Tibshirani, R., Botstein, D., Brown, P. O., Brooks, J. D., and Pollack, J. R.,
“Gene expression profiling identifies clinically relevant subtypes of prostate cancer.”,
Proc Natl Acad Sci U S A, vol. 101, no. 3, pp. 811-6, 2004.
M. van de Rijn, Perou, C. M., Tibshirani, R., Haas, P., Kallioniemi, O., Kononen, J., Torhorst, J., Sauter, G., Zuber, M., Köchli, O. R., Mross, F., Dieterich, H., Seitz, R., Ross, D., Botstein, D., and Brown, P.,
“Expression of cytokeratins 17 and 5 identifies a group of breast carcinomas with poor clinical outcome.”,
Am J Pathol, vol. 161, no. 6, pp. 1991-6, 2002.
H. Y. Chang, Sneddon, J. B., Alizadeh, A. A., Sood, R., West, R. B., Montgomery, K., Chi, J. - T., van de Rijn, M., Botstein, D., and Brown, P. O.,
“Gene expression signature of fibroblast serum response predicts human cancer progression: similarities between tumors and wounds.”,
PLoS Biol, vol. 2, no. 2, p. E7, 2004.
Phenotype
H. Y. Chang, Chi, J. - T., Dudoit, S., Bondre, C., van de Rijn, M., Botstein, D., and Brown, P. O.,
“Diversity, topographic differentiation, and positional memory in human fibroblasts.”,
Proc Natl Acad Sci U S A, vol. 99, no. 20, pp. 12877-82, 2002.
Paraffin Embedding
S. C. Linn, West, R. B., Pollack, J. R., Zhu, S., Hernandez-Boussard, T., Nielsen, T. O., Rubin, B. P., Patel, iv, R., Goldblum, J. R., Siegmund, D., Botstein, D., Brown, P. O., C Gilks, B., and van de Rijn, M.,
“Gene expression patterns and gene copy number changes in dermatofibrosarcoma protuberans.”,
Am J Pathol, vol. 163, no. 6, pp. 2383-95, 2003.
Paired Box Transcription Factors
M. E. Schaner, Ross, D. T., Ciaravino, G., Sorlie, T., Troyanskaya, O., Diehn, M., Wang, Y. C., Duran, G. E., Sikic, T. L., Caldeira, S., Skomedal, H., Tu, I. - P., Hernandez-Boussard, T., Johnson, S. W., O'Dwyer, P. J., Fero, M. J., Kristensen, G. B., Borresen-Dale, A. - L., Hastie, T., Tibshirani, R., van de Rijn, M., Teng, N. N., Longacre, T. A., Botstein, D., Brown, P. O., and Sikic, B. I.,
“Gene expression patterns in ovarian carcinomas.”,
Mol Biol Cell, vol. 14, no. 11, pp. 4376-86, 2003.
Ovarian Neoplasms
M. E. Schaner, Ross, D. T., Ciaravino, G., Sorlie, T., Troyanskaya, O., Diehn, M., Wang, Y. C., Duran, G. E., Sikic, T. L., Caldeira, S., Skomedal, H., Tu, I. - P., Hernandez-Boussard, T., Johnson, S. W., O'Dwyer, P. J., Fero, M. J., Kristensen, G. B., Borresen-Dale, A. - L., Hastie, T., Tibshirani, R., van de Rijn, M., Teng, N. N., Longacre, T. A., Botstein, D., Brown, P. O., and Sikic, B. I.,
“Gene expression patterns in ovarian carcinomas.”,
Mol Biol Cell, vol. 14, no. 11, pp. 4376-86, 2003.
Oligonucleotide Array Sequence Analysis
H. Y. Chang, Chi, J. - T., Dudoit, S., Bondre, C., van de Rijn, M., Botstein, D., and Brown, P. O.,
“Diversity, topographic differentiation, and positional memory in human fibroblasts.”,
Proc Natl Acad Sci U S A, vol. 99, no. 20, pp. 12877-82, 2002.
J. Lapointe, Li, C., Higgins, J. P., van de Rijn, M., Bair, E., Montgomery, K., Ferrari, M., Egevad, L., Rayford, W., Bergerheim, U., Ekman, P., DeMarzo, A. M., Tibshirani, R., Botstein, D., Brown, P. O., Brooks, J. D., and Pollack, J. R.,
“Gene expression profiling identifies clinically relevant subtypes of prostate cancer.”,
Proc Natl Acad Sci U S A, vol. 101, no. 3, pp. 811-6, 2004.
M. van de Rijn, Perou, C. M., Tibshirani, R., Haas, P., Kallioniemi, O., Kononen, J., Torhorst, J., Sauter, G., Zuber, M., Köchli, O. R., Mross, F., Dieterich, H., Seitz, R., Ross, D., Botstein, D., and Brown, P.,
“Expression of cytokeratins 17 and 5 identifies a group of breast carcinomas with poor clinical outcome.”,
Am J Pathol, vol. 161, no. 6, pp. 1991-6, 2002.
X. Chen, Cheung, S. Tim, So, S., Fan, S. Tat, Barry, C., Higgins, J., Lai, K. - M., Ji, J., Dudoit, S., Ng, I. O. L., van de Rijn, M., Botstein, D., and Brown, P. O.,
“Gene expression patterns in human liver cancers.”,
Mol Biol Cell, vol. 13, no. 6, pp. 1929-39, 2002.
T. O. Nielsen, Hsu, F. D., O'Connell, J. X., C Gilks, B., Sorensen, P. H. B., Linn, S., West, R. B., Liu, C. Long, Botstein, D., Brown, P. O., and van de Rijn, M.,
“Tissue microarray validation of epidermal growth factor receptor and SALL2 in synovial sarcoma with comparison to tumors of similar histology.”,
Am J Pathol, vol. 163, no. 4, pp. 1449-56, 2003.
J. R. Pollack, van de Rijn, M., and Botstein, D.,
“Challenges in developing a molecular characterization of cancer.”,
Semin Oncol, vol. 29, no. 3, pp. 280-5, 2002.
T. O. Nielsen, West, R. B., Linn, S. C., Alter, O., Knowling, M. A., O'Connell, J. X., Zhu, S., Fero, M., Sherlock, G., Pollack, J. R., Brown, P. O., Botstein, D., and van de Rijn, M.,
“Molecular characterisation of soft tissue tumours: a gene expression study.”,
Lancet, vol. 359, no. 9314, pp. 1301-7, 2002.
M. E. Schaner, Ross, D. T., Ciaravino, G., Sorlie, T., Troyanskaya, O., Diehn, M., Wang, Y. C., Duran, G. E., Sikic, T. L., Caldeira, S., Skomedal, H., Tu, I. - P., Hernandez-Boussard, T., Johnson, S. W., O'Dwyer, P. J., Fero, M. J., Kristensen, G. B., Borresen-Dale, A. - L., Hastie, T., Tibshirani, R., van de Rijn, M., Teng, N. N., Longacre, T. A., Botstein, D., Brown, P. O., and Sikic, B. I.,
“Gene expression patterns in ovarian carcinomas.”,
Mol Biol Cell, vol. 14, no. 11, pp. 4376-86, 2003.
S. C. Linn, West, R. B., Pollack, J. R., Zhu, S., Hernandez-Boussard, T., Nielsen, T. O., Rubin, B. P., Patel, iv, R., Goldblum, J. R., Siegmund, D., Botstein, D., Brown, P. O., C Gilks, B., and van de Rijn, M.,
“Gene expression patterns and gene copy number changes in dermatofibrosarcoma protuberans.”,
Am J Pathol, vol. 163, no. 6, pp. 2383-95, 2003.
R. Shyamsundar, Kim, Y. H., Higgins, J. P., Montgomery, K., Jorden, M., Sethuraman, A., van de Rijn, M., Botstein, D., Brown, P. O., and Pollack, J. R.,
“A DNA microarray survey of gene expression in normal human tissues.”,
Genome Biol, vol. 6, no. 3, p. R22, 2005.
Nucleic Acid Hybridization
S. C. Linn, West, R. B., Pollack, J. R., Zhu, S., Hernandez-Boussard, T., Nielsen, T. O., Rubin, B. P., Patel, iv, R., Goldblum, J. R., Siegmund, D., Botstein, D., Brown, P. O., C Gilks, B., and van de Rijn, M.,
“Gene expression patterns and gene copy number changes in dermatofibrosarcoma protuberans.”,
Am J Pathol, vol. 163, no. 6, pp. 2383-95, 2003.
Nuclear Proteins
M. E. Schaner, Ross, D. T., Ciaravino, G., Sorlie, T., Troyanskaya, O., Diehn, M., Wang, Y. C., Duran, G. E., Sikic, T. L., Caldeira, S., Skomedal, H., Tu, I. - P., Hernandez-Boussard, T., Johnson, S. W., O'Dwyer, P. J., Fero, M. J., Kristensen, G. B., Borresen-Dale, A. - L., Hastie, T., Tibshirani, R., van de Rijn, M., Teng, N. N., Longacre, T. A., Botstein, D., Brown, P. O., and Sikic, B. I.,
“Gene expression patterns in ovarian carcinomas.”,
Mol Biol Cell, vol. 14, no. 11, pp. 4376-86, 2003.
Neoplasms
J. R. Pollack, van de Rijn, M., and Botstein, D.,
“Challenges in developing a molecular characterization of cancer.”,
Semin Oncol, vol. 29, no. 3, pp. 280-5, 2002.
H. Y. Chang, Sneddon, J. B., Alizadeh, A. A., Sood, R., West, R. B., Montgomery, K., Chi, J. - T., van de Rijn, M., Botstein, D., and Brown, P. O.,
“Gene expression signature of fibroblast serum response predicts human cancer progression: similarities between tumors and wounds.”,
PLoS Biol, vol. 2, no. 2, p. E7, 2004.
Neoplasm Staging
M. van de Rijn, Perou, C. M., Tibshirani, R., Haas, P., Kallioniemi, O., Kononen, J., Torhorst, J., Sauter, G., Zuber, M., Köchli, O. R., Mross, F., Dieterich, H., Seitz, R., Ross, D., Botstein, D., and Brown, P.,
“Expression of cytokeratins 17 and 5 identifies a group of breast carcinomas with poor clinical outcome.”,
Am J Pathol, vol. 161, no. 6, pp. 1991-6, 2002.
Neoplasm Proteins
M. E. Schaner, Ross, D. T., Ciaravino, G., Sorlie, T., Troyanskaya, O., Diehn, M., Wang, Y. C., Duran, G. E., Sikic, T. L., Caldeira, S., Skomedal, H., Tu, I. - P., Hernandez-Boussard, T., Johnson, S. W., O'Dwyer, P. J., Fero, M. J., Kristensen, G. B., Borresen-Dale, A. - L., Hastie, T., Tibshirani, R., van de Rijn, M., Teng, N. N., Longacre, T. A., Botstein, D., Brown, P. O., and Sikic, B. I.,
“Gene expression patterns in ovarian carcinomas.”,
Mol Biol Cell, vol. 14, no. 11, pp. 4376-86, 2003.
Neoplasm Invasiveness
H. Y. Chang, Sneddon, J. B., Alizadeh, A. A., Sood, R., West, R. B., Montgomery, K., Chi, J. - T., van de Rijn, M., Botstein, D., and Brown, P. O.,
“Gene expression signature of fibroblast serum response predicts human cancer progression: similarities between tumors and wounds.”,
PLoS Biol, vol. 2, no. 2, p. E7, 2004.
Mucin-1
J. Lapointe, Li, C., Higgins, J. P., van de Rijn, M., Bair, E., Montgomery, K., Ferrari, M., Egevad, L., Rayford, W., Bergerheim, U., Ekman, P., DeMarzo, A. M., Tibshirani, R., Botstein, D., Brown, P. O., Brooks, J. D., and Pollack, J. R.,
“Gene expression profiling identifies clinically relevant subtypes of prostate cancer.”,
Proc Natl Acad Sci U S A, vol. 101, no. 3, pp. 811-6, 2004.
Middle Aged
S. C. Linn, West, R. B., Pollack, J. R., Zhu, S., Hernandez-Boussard, T., Nielsen, T. O., Rubin, B. P., Patel, iv, R., Goldblum, J. R., Siegmund, D., Botstein, D., Brown, P. O., C Gilks, B., and van de Rijn, M.,
“Gene expression patterns and gene copy number changes in dermatofibrosarcoma protuberans.”,
Am J Pathol, vol. 163, no. 6, pp. 2383-95, 2003.
Microscopy, Fluorescence
H. Y. Chang, Chi, J. - T., Dudoit, S., Bondre, C., van de Rijn, M., Botstein, D., and Brown, P. O.,
“Diversity, topographic differentiation, and positional memory in human fibroblasts.”,
Proc Natl Acad Sci U S A, vol. 99, no. 20, pp. 12877-82, 2002.
Membrane Glycoproteins
M. E. Schaner, Ross, D. T., Ciaravino, G., Sorlie, T., Troyanskaya, O., Diehn, M., Wang, Y. C., Duran, G. E., Sikic, T. L., Caldeira, S., Skomedal, H., Tu, I. - P., Hernandez-Boussard, T., Johnson, S. W., O'Dwyer, P. J., Fero, M. J., Kristensen, G. B., Borresen-Dale, A. - L., Hastie, T., Tibshirani, R., van de Rijn, M., Teng, N. N., Longacre, T. A., Botstein, D., Brown, P. O., and Sikic, B. I.,
“Gene expression patterns in ovarian carcinomas.”,
Mol Biol Cell, vol. 14, no. 11, pp. 4376-86, 2003.
Male
J. Lapointe, Li, C., Higgins, J. P., van de Rijn, M., Bair, E., Montgomery, K., Ferrari, M., Egevad, L., Rayford, W., Bergerheim, U., Ekman, P., DeMarzo, A. M., Tibshirani, R., Botstein, D., Brown, P. O., Brooks, J. D., and Pollack, J. R.,
“Gene expression profiling identifies clinically relevant subtypes of prostate cancer.”,
Proc Natl Acad Sci U S A, vol. 101, no. 3, pp. 811-6, 2004.
S. C. Linn, West, R. B., Pollack, J. R., Zhu, S., Hernandez-Boussard, T., Nielsen, T. O., Rubin, B. P., Patel, iv, R., Goldblum, J. R., Siegmund, D., Botstein, D., Brown, P. O., C Gilks, B., and van de Rijn, M.,
“Gene expression patterns and gene copy number changes in dermatofibrosarcoma protuberans.”,
Am J Pathol, vol. 163, no. 6, pp. 2383-95, 2003.
Lymphatic Metastasis
J. Lapointe, Li, C., Higgins, J. P., van de Rijn, M., Bair, E., Montgomery, K., Ferrari, M., Egevad, L., Rayford, W., Bergerheim, U., Ekman, P., DeMarzo, A. M., Tibshirani, R., Botstein, D., Brown, P. O., Brooks, J. D., and Pollack, J. R.,
“Gene expression profiling identifies clinically relevant subtypes of prostate cancer.”,
Proc Natl Acad Sci U S A, vol. 101, no. 3, pp. 811-6, 2004.
Liver Neoplasms
X. Chen, Cheung, S. Tim, So, S., Fan, S. Tat, Barry, C., Higgins, J., Lai, K. - M., Ji, J., Dudoit, S., Ng, I. O. L., van de Rijn, M., Botstein, D., and Brown, P. O.,
“Gene expression patterns in human liver cancers.”,
Mol Biol Cell, vol. 13, no. 6, pp. 1929-39, 2002.
Liver
X. Chen, Cheung, S. Tim, So, S., Fan, S. Tat, Barry, C., Higgins, J., Lai, K. - M., Ji, J., Dudoit, S., Ng, I. O. L., van de Rijn, M., Botstein, D., and Brown, P. O.,
“Gene expression patterns in human liver cancers.”,
Mol Biol Cell, vol. 13, no. 6, pp. 1929-39, 2002.
Lipid Metabolism
H. Y. Chang, Chi, J. - T., Dudoit, S., Bondre, C., van de Rijn, M., Botstein, D., and Brown, P. O.,
“Diversity, topographic differentiation, and positional memory in human fibroblasts.”,
Proc Natl Acad Sci U S A, vol. 99, no. 20, pp. 12877-82, 2002.
Keratins
M. van de Rijn, Perou, C. M., Tibshirani, R., Haas, P., Kallioniemi, O., Kononen, J., Torhorst, J., Sauter, G., Zuber, M., Köchli, O. R., Mross, F., Dieterich, H., Seitz, R., Ross, D., Botstein, D., and Brown, P.,
“Expression of cytokeratins 17 and 5 identifies a group of breast carcinomas with poor clinical outcome.”,
Am J Pathol, vol. 161, no. 6, pp. 1991-6, 2002.
Keratin-5
M. van de Rijn, Perou, C. M., Tibshirani, R., Haas, P., Kallioniemi, O., Kononen, J., Torhorst, J., Sauter, G., Zuber, M., Köchli, O. R., Mross, F., Dieterich, H., Seitz, R., Ross, D., Botstein, D., and Brown, P.,
“Expression of cytokeratins 17 and 5 identifies a group of breast carcinomas with poor clinical outcome.”,
Am J Pathol, vol. 161, no. 6, pp. 1991-6, 2002.
Immunohistochemistry
M. van de Rijn, Perou, C. M., Tibshirani, R., Haas, P., Kallioniemi, O., Kononen, J., Torhorst, J., Sauter, G., Zuber, M., Köchli, O. R., Mross, F., Dieterich, H., Seitz, R., Ross, D., Botstein, D., and Brown, P.,
“Expression of cytokeratins 17 and 5 identifies a group of breast carcinomas with poor clinical outcome.”,
Am J Pathol, vol. 161, no. 6, pp. 1991-6, 2002.
T. O. Nielsen, Hsu, F. D., O'Connell, J. X., C Gilks, B., Sorensen, P. H. B., Linn, S., West, R. B., Liu, C. Long, Botstein, D., Brown, P. O., and van de Rijn, M.,
“Tissue microarray validation of epidermal growth factor receptor and SALL2 in synovial sarcoma with comparison to tumors of similar histology.”,
Am J Pathol, vol. 163, no. 4, pp. 1449-56, 2003.
M. E. Schaner, Ross, D. T., Ciaravino, G., Sorlie, T., Troyanskaya, O., Diehn, M., Wang, Y. C., Duran, G. E., Sikic, T. L., Caldeira, S., Skomedal, H., Tu, I. - P., Hernandez-Boussard, T., Johnson, S. W., O'Dwyer, P. J., Fero, M. J., Kristensen, G. B., Borresen-Dale, A. - L., Hastie, T., Tibshirani, R., van de Rijn, M., Teng, N. N., Longacre, T. A., Botstein, D., Brown, P. O., and Sikic, B. I.,
“Gene expression patterns in ovarian carcinomas.”,
Mol Biol Cell, vol. 14, no. 11, pp. 4376-86, 2003.
S. C. Linn, West, R. B., Pollack, J. R., Zhu, S., Hernandez-Boussard, T., Nielsen, T. O., Rubin, B. P., Patel, iv, R., Goldblum, J. R., Siegmund, D., Botstein, D., Brown, P. O., C Gilks, B., and van de Rijn, M.,
“Gene expression patterns and gene copy number changes in dermatofibrosarcoma protuberans.”,
Am J Pathol, vol. 163, no. 6, pp. 2383-95, 2003.
Humans
H. Y. Chang, Chi, J. - T., Dudoit, S., Bondre, C., van de Rijn, M., Botstein, D., and Brown, P. O.,
“Diversity, topographic differentiation, and positional memory in human fibroblasts.”,
Proc Natl Acad Sci U S A, vol. 99, no. 20, pp. 12877-82, 2002.
J. Lapointe, Li, C., Higgins, J. P., van de Rijn, M., Bair, E., Montgomery, K., Ferrari, M., Egevad, L., Rayford, W., Bergerheim, U., Ekman, P., DeMarzo, A. M., Tibshirani, R., Botstein, D., Brown, P. O., Brooks, J. D., and Pollack, J. R.,
“Gene expression profiling identifies clinically relevant subtypes of prostate cancer.”,
Proc Natl Acad Sci U S A, vol. 101, no. 3, pp. 811-6, 2004.
M. van de Rijn, Perou, C. M., Tibshirani, R., Haas, P., Kallioniemi, O., Kononen, J., Torhorst, J., Sauter, G., Zuber, M., Köchli, O. R., Mross, F., Dieterich, H., Seitz, R., Ross, D., Botstein, D., and Brown, P.,
“Expression of cytokeratins 17 and 5 identifies a group of breast carcinomas with poor clinical outcome.”,
Am J Pathol, vol. 161, no. 6, pp. 1991-6, 2002.
X. Chen, Cheung, S. Tim, So, S., Fan, S. Tat, Barry, C., Higgins, J., Lai, K. - M., Ji, J., Dudoit, S., Ng, I. O. L., van de Rijn, M., Botstein, D., and Brown, P. O.,
“Gene expression patterns in human liver cancers.”,
Mol Biol Cell, vol. 13, no. 6, pp. 1929-39, 2002.
T. O. Nielsen, Hsu, F. D., O'Connell, J. X., C Gilks, B., Sorensen, P. H. B., Linn, S., West, R. B., Liu, C. Long, Botstein, D., Brown, P. O., and van de Rijn, M.,
“Tissue microarray validation of epidermal growth factor receptor and SALL2 in synovial sarcoma with comparison to tumors of similar histology.”,
Am J Pathol, vol. 163, no. 4, pp. 1449-56, 2003.
J. R. Pollack, van de Rijn, M., and Botstein, D.,
“Challenges in developing a molecular characterization of cancer.”,
Semin Oncol, vol. 29, no. 3, pp. 280-5, 2002.
M. E. Schaner, Ross, D. T., Ciaravino, G., Sorlie, T., Troyanskaya, O., Diehn, M., Wang, Y. C., Duran, G. E., Sikic, T. L., Caldeira, S., Skomedal, H., Tu, I. - P., Hernandez-Boussard, T., Johnson, S. W., O'Dwyer, P. J., Fero, M. J., Kristensen, G. B., Borresen-Dale, A. - L., Hastie, T., Tibshirani, R., van de Rijn, M., Teng, N. N., Longacre, T. A., Botstein, D., Brown, P. O., and Sikic, B. I.,
“Gene expression patterns in ovarian carcinomas.”,
Mol Biol Cell, vol. 14, no. 11, pp. 4376-86, 2003.
T. O. Nielsen, West, R. B., Linn, S. C., Alter, O., Knowling, M. A., O'Connell, J. X., Zhu, S., Fero, M., Sherlock, G., Pollack, J. R., Brown, P. O., Botstein, D., and van de Rijn, M.,
“Molecular characterisation of soft tissue tumours: a gene expression study.”,
Lancet, vol. 359, no. 9314, pp. 1301-7, 2002.
S. C. Linn, West, R. B., Pollack, J. R., Zhu, S., Hernandez-Boussard, T., Nielsen, T. O., Rubin, B. P., Patel, iv, R., Goldblum, J. R., Siegmund, D., Botstein, D., Brown, P. O., C Gilks, B., and van de Rijn, M.,
“Gene expression patterns and gene copy number changes in dermatofibrosarcoma protuberans.”,
Am J Pathol, vol. 163, no. 6, pp. 2383-95, 2003.
J. - T. Chi, Chang, H. Y., Haraldsen, G., Jahnsen, F. L., Troyanskaya, O. G., Chang, D. S., Wang, Z., Rockson, S. G., van de Rijn, M., Botstein, D., and Brown, P. O.,
“Endothelial cell diversity revealed by global expression profiling.”,
Proc Natl Acad Sci U S A, vol. 100, no. 19, pp. 10623-8, 2003.
R. Shyamsundar, Kim, Y. H., Higgins, J. P., Montgomery, K., Jorden, M., Sethuraman, A., van de Rijn, M., Botstein, D., Brown, P. O., and Pollack, J. R.,
“A DNA microarray survey of gene expression in normal human tissues.”,
Genome Biol, vol. 6, no. 3, p. R22, 2005.
H. Y. Chang, Sneddon, J. B., Alizadeh, A. A., Sood, R., West, R. B., Montgomery, K., Chi, J. - T., van de Rijn, M., Botstein, D., and Brown, P. O.,
“Gene expression signature of fibroblast serum response predicts human cancer progression: similarities between tumors and wounds.”,
PLoS Biol, vol. 2, no. 2, p. E7, 2004.
Homeodomain Proteins
H. Y. Chang, Chi, J. - T., Dudoit, S., Bondre, C., van de Rijn, M., Botstein, D., and Brown, P. O.,
“Diversity, topographic differentiation, and positional memory in human fibroblasts.”,
Proc Natl Acad Sci U S A, vol. 99, no. 20, pp. 12877-82, 2002.
GPI-Linked Proteins
M. E. Schaner, Ross, D. T., Ciaravino, G., Sorlie, T., Troyanskaya, O., Diehn, M., Wang, Y. C., Duran, G. E., Sikic, T. L., Caldeira, S., Skomedal, H., Tu, I. - P., Hernandez-Boussard, T., Johnson, S. W., O'Dwyer, P. J., Fero, M. J., Kristensen, G. B., Borresen-Dale, A. - L., Hastie, T., Tibshirani, R., van de Rijn, M., Teng, N. N., Longacre, T. A., Botstein, D., Brown, P. O., and Sikic, B. I.,
“Gene expression patterns in ovarian carcinomas.”,
Mol Biol Cell, vol. 14, no. 11, pp. 4376-86, 2003.
Genotype
X. Chen, Cheung, S. Tim, So, S., Fan, S. Tat, Barry, C., Higgins, J., Lai, K. - M., Ji, J., Dudoit, S., Ng, I. O. L., van de Rijn, M., Botstein, D., and Brown, P. O.,
“Gene expression patterns in human liver cancers.”,
Mol Biol Cell, vol. 13, no. 6, pp. 1929-39, 2002.
Genomics
R. Shyamsundar, Kim, Y. H., Higgins, J. P., Montgomery, K., Jorden, M., Sethuraman, A., van de Rijn, M., Botstein, D., Brown, P. O., and Pollack, J. R.,
“A DNA microarray survey of gene expression in normal human tissues.”,
Genome Biol, vol. 6, no. 3, p. R22, 2005.
Genetic Variation
X. Chen, Cheung, S. Tim, So, S., Fan, S. Tat, Barry, C., Higgins, J., Lai, K. - M., Ji, J., Dudoit, S., Ng, I. O. L., van de Rijn, M., Botstein, D., and Brown, P. O.,
“Gene expression patterns in human liver cancers.”,
Mol Biol Cell, vol. 13, no. 6, pp. 1929-39, 2002.
Genes, p53
X. Chen, Cheung, S. Tim, So, S., Fan, S. Tat, Barry, C., Higgins, J., Lai, K. - M., Ji, J., Dudoit, S., Ng, I. O. L., van de Rijn, M., Botstein, D., and Brown, P. O.,
“Gene expression patterns in human liver cancers.”,
Mol Biol Cell, vol. 13, no. 6, pp. 1929-39, 2002.
Gene Expression Regulation, Neoplastic
X. Chen, Cheung, S. Tim, So, S., Fan, S. Tat, Barry, C., Higgins, J., Lai, K. - M., Ji, J., Dudoit, S., Ng, I. O. L., van de Rijn, M., Botstein, D., and Brown, P. O.,
“Gene expression patterns in human liver cancers.”,
Mol Biol Cell, vol. 13, no. 6, pp. 1929-39, 2002.
T. O. Nielsen, West, R. B., Linn, S. C., Alter, O., Knowling, M. A., O'Connell, J. X., Zhu, S., Fero, M., Sherlock, G., Pollack, J. R., Brown, P. O., Botstein, D., and van de Rijn, M.,
“Molecular characterisation of soft tissue tumours: a gene expression study.”,
Lancet, vol. 359, no. 9314, pp. 1301-7, 2002.
H. Y. Chang, Sneddon, J. B., Alizadeh, A. A., Sood, R., West, R. B., Montgomery, K., Chi, J. - T., van de Rijn, M., Botstein, D., and Brown, P. O.,
“Gene expression signature of fibroblast serum response predicts human cancer progression: similarities between tumors and wounds.”,
PLoS Biol, vol. 2, no. 2, p. E7, 2004.
Gene Expression Regulation
J. - T. Chi, Chang, H. Y., Haraldsen, G., Jahnsen, F. L., Troyanskaya, O. G., Chang, D. S., Wang, Z., Rockson, S. G., van de Rijn, M., Botstein, D., and Brown, P. O.,
“Endothelial cell diversity revealed by global expression profiling.”,
Proc Natl Acad Sci U S A, vol. 100, no. 19, pp. 10623-8, 2003.
H. Y. Chang, Sneddon, J. B., Alizadeh, A. A., Sood, R., West, R. B., Montgomery, K., Chi, J. - T., van de Rijn, M., Botstein, D., and Brown, P. O.,
“Gene expression signature of fibroblast serum response predicts human cancer progression: similarities between tumors and wounds.”,
PLoS Biol, vol. 2, no. 2, p. E7, 2004.
Gene Expression Profiling
J. Lapointe, Li, C., Higgins, J. P., van de Rijn, M., Bair, E., Montgomery, K., Ferrari, M., Egevad, L., Rayford, W., Bergerheim, U., Ekman, P., DeMarzo, A. M., Tibshirani, R., Botstein, D., Brown, P. O., Brooks, J. D., and Pollack, J. R.,
“Gene expression profiling identifies clinically relevant subtypes of prostate cancer.”,
Proc Natl Acad Sci U S A, vol. 101, no. 3, pp. 811-6, 2004.
J. R. Pollack, van de Rijn, M., and Botstein, D.,
“Challenges in developing a molecular characterization of cancer.”,
Semin Oncol, vol. 29, no. 3, pp. 280-5, 2002.
T. O. Nielsen, West, R. B., Linn, S. C., Alter, O., Knowling, M. A., O'Connell, J. X., Zhu, S., Fero, M., Sherlock, G., Pollack, J. R., Brown, P. O., Botstein, D., and van de Rijn, M.,
“Molecular characterisation of soft tissue tumours: a gene expression study.”,
Lancet, vol. 359, no. 9314, pp. 1301-7, 2002.
S. C. Linn, West, R. B., Pollack, J. R., Zhu, S., Hernandez-Boussard, T., Nielsen, T. O., Rubin, B. P., Patel, iv, R., Goldblum, J. R., Siegmund, D., Botstein, D., Brown, P. O., C Gilks, B., and van de Rijn, M.,
“Gene expression patterns and gene copy number changes in dermatofibrosarcoma protuberans.”,
Am J Pathol, vol. 163, no. 6, pp. 2383-95, 2003.
J. - T. Chi, Chang, H. Y., Haraldsen, G., Jahnsen, F. L., Troyanskaya, O. G., Chang, D. S., Wang, Z., Rockson, S. G., van de Rijn, M., Botstein, D., and Brown, P. O.,
“Endothelial cell diversity revealed by global expression profiling.”,
Proc Natl Acad Sci U S A, vol. 100, no. 19, pp. 10623-8, 2003.
R. Shyamsundar, Kim, Y. H., Higgins, J. P., Montgomery, K., Jorden, M., Sethuraman, A., van de Rijn, M., Botstein, D., Brown, P. O., and Pollack, J. R.,
“A DNA microarray survey of gene expression in normal human tissues.”,
Genome Biol, vol. 6, no. 3, p. R22, 2005.
Gene Expression
S. C. Linn, West, R. B., Pollack, J. R., Zhu, S., Hernandez-Boussard, T., Nielsen, T. O., Rubin, B. P., Patel, iv, R., Goldblum, J. R., Siegmund, D., Botstein, D., Brown, P. O., C Gilks, B., and van de Rijn, M.,
“Gene expression patterns and gene copy number changes in dermatofibrosarcoma protuberans.”,
Am J Pathol, vol. 163, no. 6, pp. 2383-95, 2003.
Gene Dosage
S. C. Linn, West, R. B., Pollack, J. R., Zhu, S., Hernandez-Boussard, T., Nielsen, T. O., Rubin, B. P., Patel, iv, R., Goldblum, J. R., Siegmund, D., Botstein, D., Brown, P. O., C Gilks, B., and van de Rijn, M.,
“Gene expression patterns and gene copy number changes in dermatofibrosarcoma protuberans.”,
Am J Pathol, vol. 163, no. 6, pp. 2383-95, 2003.
GATA3 Transcription Factor
M. E. Schaner, Ross, D. T., Ciaravino, G., Sorlie, T., Troyanskaya, O., Diehn, M., Wang, Y. C., Duran, G. E., Sikic, T. L., Caldeira, S., Skomedal, H., Tu, I. - P., Hernandez-Boussard, T., Johnson, S. W., O'Dwyer, P. J., Fero, M. J., Kristensen, G. B., Borresen-Dale, A. - L., Hastie, T., Tibshirani, R., van de Rijn, M., Teng, N. N., Longacre, T. A., Botstein, D., Brown, P. O., and Sikic, B. I.,
“Gene expression patterns in ovarian carcinomas.”,
Mol Biol Cell, vol. 14, no. 11, pp. 4376-86, 2003.
Formaldehyde
S. C. Linn, West, R. B., Pollack, J. R., Zhu, S., Hernandez-Boussard, T., Nielsen, T. O., Rubin, B. P., Patel, iv, R., Goldblum, J. R., Siegmund, D., Botstein, D., Brown, P. O., C Gilks, B., and van de Rijn, M.,
“Gene expression patterns and gene copy number changes in dermatofibrosarcoma protuberans.”,
Am J Pathol, vol. 163, no. 6, pp. 2383-95, 2003.
Fixatives
S. C. Linn, West, R. B., Pollack, J. R., Zhu, S., Hernandez-Boussard, T., Nielsen, T. O., Rubin, B. P., Patel, iv, R., Goldblum, J. R., Siegmund, D., Botstein, D., Brown, P. O., C Gilks, B., and van de Rijn, M.,
“Gene expression patterns and gene copy number changes in dermatofibrosarcoma protuberans.”,
Am J Pathol, vol. 163, no. 6, pp. 2383-95, 2003.
Fibroblasts
H. Y. Chang, Chi, J. - T., Dudoit, S., Bondre, C., van de Rijn, M., Botstein, D., and Brown, P. O.,
“Diversity, topographic differentiation, and positional memory in human fibroblasts.”,
Proc Natl Acad Sci U S A, vol. 99, no. 20, pp. 12877-82, 2002.
H. Y. Chang, Sneddon, J. B., Alizadeh, A. A., Sood, R., West, R. B., Montgomery, K., Chi, J. - T., van de Rijn, M., Botstein, D., and Brown, P. O.,
“Gene expression signature of fibroblast serum response predicts human cancer progression: similarities between tumors and wounds.”,
PLoS Biol, vol. 2, no. 2, p. E7, 2004.
Female
M. van de Rijn, Perou, C. M., Tibshirani, R., Haas, P., Kallioniemi, O., Kononen, J., Torhorst, J., Sauter, G., Zuber, M., Köchli, O. R., Mross, F., Dieterich, H., Seitz, R., Ross, D., Botstein, D., and Brown, P.,
“Expression of cytokeratins 17 and 5 identifies a group of breast carcinomas with poor clinical outcome.”,
Am J Pathol, vol. 161, no. 6, pp. 1991-6, 2002.
M. E. Schaner, Ross, D. T., Ciaravino, G., Sorlie, T., Troyanskaya, O., Diehn, M., Wang, Y. C., Duran, G. E., Sikic, T. L., Caldeira, S., Skomedal, H., Tu, I. - P., Hernandez-Boussard, T., Johnson, S. W., O'Dwyer, P. J., Fero, M. J., Kristensen, G. B., Borresen-Dale, A. - L., Hastie, T., Tibshirani, R., van de Rijn, M., Teng, N. N., Longacre, T. A., Botstein, D., Brown, P. O., and Sikic, B. I.,
“Gene expression patterns in ovarian carcinomas.”,
Mol Biol Cell, vol. 14, no. 11, pp. 4376-86, 2003.
S. C. Linn, West, R. B., Pollack, J. R., Zhu, S., Hernandez-Boussard, T., Nielsen, T. O., Rubin, B. P., Patel, iv, R., Goldblum, J. R., Siegmund, D., Botstein, D., Brown, P. O., C Gilks, B., and van de Rijn, M.,
“Gene expression patterns and gene copy number changes in dermatofibrosarcoma protuberans.”,
Am J Pathol, vol. 163, no. 6, pp. 2383-95, 2003.
Ephrin-B1
M. E. Schaner, Ross, D. T., Ciaravino, G., Sorlie, T., Troyanskaya, O., Diehn, M., Wang, Y. C., Duran, G. E., Sikic, T. L., Caldeira, S., Skomedal, H., Tu, I. - P., Hernandez-Boussard, T., Johnson, S. W., O'Dwyer, P. J., Fero, M. J., Kristensen, G. B., Borresen-Dale, A. - L., Hastie, T., Tibshirani, R., van de Rijn, M., Teng, N. N., Longacre, T. A., Botstein, D., Brown, P. O., and Sikic, B. I.,
“Gene expression patterns in ovarian carcinomas.”,
Mol Biol Cell, vol. 14, no. 11, pp. 4376-86, 2003.
Endothelium, Vascular
J. - T. Chi, Chang, H. Y., Haraldsen, G., Jahnsen, F. L., Troyanskaya, O. G., Chang, D. S., Wang, Z., Rockson, S. G., van de Rijn, M., Botstein, D., and Brown, P. O.,
“Endothelial cell diversity revealed by global expression profiling.”,
Proc Natl Acad Sci U S A, vol. 100, no. 19, pp. 10623-8, 2003.
DNA-Binding Proteins
M. E. Schaner, Ross, D. T., Ciaravino, G., Sorlie, T., Troyanskaya, O., Diehn, M., Wang, Y. C., Duran, G. E., Sikic, T. L., Caldeira, S., Skomedal, H., Tu, I. - P., Hernandez-Boussard, T., Johnson, S. W., O'Dwyer, P. J., Fero, M. J., Kristensen, G. B., Borresen-Dale, A. - L., Hastie, T., Tibshirani, R., van de Rijn, M., Teng, N. N., Longacre, T. A., Botstein, D., Brown, P. O., and Sikic, B. I.,
“Gene expression patterns in ovarian carcinomas.”,
Mol Biol Cell, vol. 14, no. 11, pp. 4376-86, 2003.
Disease Progression
H. Y. Chang, Sneddon, J. B., Alizadeh, A. A., Sood, R., West, R. B., Montgomery, K., Chi, J. - T., van de Rijn, M., Botstein, D., and Brown, P. O.,
“Gene expression signature of fibroblast serum response predicts human cancer progression: similarities between tumors and wounds.”,
PLoS Biol, vol. 2, no. 2, p. E7, 2004.
Diagnosis, Differential
T. O. Nielsen, Hsu, F. D., O'Connell, J. X., C Gilks, B., Sorensen, P. H. B., Linn, S., West, R. B., Liu, C. Long, Botstein, D., Brown, P. O., and van de Rijn, M.,
“Tissue microarray validation of epidermal growth factor receptor and SALL2 in synovial sarcoma with comparison to tumors of similar histology.”,
Am J Pathol, vol. 163, no. 4, pp. 1449-56, 2003.
Dermatofibrosarcoma
S. C. Linn, West, R. B., Pollack, J. R., Zhu, S., Hernandez-Boussard, T., Nielsen, T. O., Rubin, B. P., Patel, iv, R., Goldblum, J. R., Siegmund, D., Botstein, D., Brown, P. O., C Gilks, B., and van de Rijn, M.,
“Gene expression patterns and gene copy number changes in dermatofibrosarcoma protuberans.”,
Am J Pathol, vol. 163, no. 6, pp. 2383-95, 2003.
Culture Media, Serum-Free
H. Y. Chang, Chi, J. - T., Dudoit, S., Bondre, C., van de Rijn, M., Botstein, D., and Brown, P. O.,
“Diversity, topographic differentiation, and positional memory in human fibroblasts.”,
Proc Natl Acad Sci U S A, vol. 99, no. 20, pp. 12877-82, 2002.
Cryopreservation
S. C. Linn, West, R. B., Pollack, J. R., Zhu, S., Hernandez-Boussard, T., Nielsen, T. O., Rubin, B. P., Patel, iv, R., Goldblum, J. R., Siegmund, D., Botstein, D., Brown, P. O., C Gilks, B., and van de Rijn, M.,
“Gene expression patterns and gene copy number changes in dermatofibrosarcoma protuberans.”,
Am J Pathol, vol. 163, no. 6, pp. 2383-95, 2003.
Cluster Analysis
T. O. Nielsen, Hsu, F. D., O'Connell, J. X., C Gilks, B., Sorensen, P. H. B., Linn, S., West, R. B., Liu, C. Long, Botstein, D., Brown, P. O., and van de Rijn, M.,
“Tissue microarray validation of epidermal growth factor receptor and SALL2 in synovial sarcoma with comparison to tumors of similar histology.”,
Am J Pathol, vol. 163, no. 4, pp. 1449-56, 2003.
R. Shyamsundar, Kim, Y. H., Higgins, J. P., Montgomery, K., Jorden, M., Sethuraman, A., van de Rijn, M., Botstein, D., Brown, P. O., and Pollack, J. R.,
“A DNA microarray survey of gene expression in normal human tissues.”,
Genome Biol, vol. 6, no. 3, p. R22, 2005.
Cells, Cultured
J. - T. Chi, Chang, H. Y., Haraldsen, G., Jahnsen, F. L., Troyanskaya, O. G., Chang, D. S., Wang, Z., Rockson, S. G., van de Rijn, M., Botstein, D., and Brown, P. O.,
“Endothelial cell diversity revealed by global expression profiling.”,
Proc Natl Acad Sci U S A, vol. 100, no. 19, pp. 10623-8, 2003.
H. Y. Chang, Chi, J. - T., Dudoit, S., Bondre, C., van de Rijn, M., Botstein, D., and Brown, P. O.,
“Diversity, topographic differentiation, and positional memory in human fibroblasts.”,
Proc Natl Acad Sci U S A, vol. 99, no. 20, pp. 12877-82, 2002.
Cell Movement
H. Y. Chang, Chi, J. - T., Dudoit, S., Bondre, C., van de Rijn, M., Botstein, D., and Brown, P. O.,
“Diversity, topographic differentiation, and positional memory in human fibroblasts.”,
Proc Natl Acad Sci U S A, vol. 99, no. 20, pp. 12877-82, 2002.
Cell Division
X. Chen, Cheung, S. Tim, So, S., Fan, S. Tat, Barry, C., Higgins, J., Lai, K. - M., Ji, J., Dudoit, S., Ng, I. O. L., van de Rijn, M., Botstein, D., and Brown, P. O.,
“Gene expression patterns in human liver cancers.”,
Mol Biol Cell, vol. 13, no. 6, pp. 1929-39, 2002.
Cell Differentiation
H. Y. Chang, Chi, J. - T., Dudoit, S., Bondre, C., van de Rijn, M., Botstein, D., and Brown, P. O.,
“Diversity, topographic differentiation, and positional memory in human fibroblasts.”,
Proc Natl Acad Sci U S A, vol. 99, no. 20, pp. 12877-82, 2002.
Cation Transport Proteins
M. E. Schaner, Ross, D. T., Ciaravino, G., Sorlie, T., Troyanskaya, O., Diehn, M., Wang, Y. C., Duran, G. E., Sikic, T. L., Caldeira, S., Skomedal, H., Tu, I. - P., Hernandez-Boussard, T., Johnson, S. W., O'Dwyer, P. J., Fero, M. J., Kristensen, G. B., Borresen-Dale, A. - L., Hastie, T., Tibshirani, R., van de Rijn, M., Teng, N. N., Longacre, T. A., Botstein, D., Brown, P. O., and Sikic, B. I.,
“Gene expression patterns in ovarian carcinomas.”,
Mol Biol Cell, vol. 14, no. 11, pp. 4376-86, 2003.
Case-Control Studies
J. Lapointe, Li, C., Higgins, J. P., van de Rijn, M., Bair, E., Montgomery, K., Ferrari, M., Egevad, L., Rayford, W., Bergerheim, U., Ekman, P., DeMarzo, A. M., Tibshirani, R., Botstein, D., Brown, P. O., Brooks, J. D., and Pollack, J. R.,
“Gene expression profiling identifies clinically relevant subtypes of prostate cancer.”,
Proc Natl Acad Sci U S A, vol. 101, no. 3, pp. 811-6, 2004.
Carcinoma, Papillary
M. E. Schaner, Ross, D. T., Ciaravino, G., Sorlie, T., Troyanskaya, O., Diehn, M., Wang, Y. C., Duran, G. E., Sikic, T. L., Caldeira, S., Skomedal, H., Tu, I. - P., Hernandez-Boussard, T., Johnson, S. W., O'Dwyer, P. J., Fero, M. J., Kristensen, G. B., Borresen-Dale, A. - L., Hastie, T., Tibshirani, R., van de Rijn, M., Teng, N. N., Longacre, T. A., Botstein, D., Brown, P. O., and Sikic, B. I.,
“Gene expression patterns in ovarian carcinomas.”,
Mol Biol Cell, vol. 14, no. 11, pp. 4376-86, 2003.
Carcinoma, Hepatocellular
X. Chen, Cheung, S. Tim, So, S., Fan, S. Tat, Barry, C., Higgins, J., Lai, K. - M., Ji, J., Dudoit, S., Ng, I. O. L., van de Rijn, M., Botstein, D., and Brown, P. O.,
“Gene expression patterns in human liver cancers.”,
Mol Biol Cell, vol. 13, no. 6, pp. 1929-39, 2002.
Breast Neoplasms
M. van de Rijn, Perou, C. M., Tibshirani, R., Haas, P., Kallioniemi, O., Kononen, J., Torhorst, J., Sauter, G., Zuber, M., Köchli, O. R., Mross, F., Dieterich, H., Seitz, R., Ross, D., Botstein, D., and Brown, P.,
“Expression of cytokeratins 17 and 5 identifies a group of breast carcinomas with poor clinical outcome.”,
Am J Pathol, vol. 161, no. 6, pp. 1991-6, 2002.
M. E. Schaner, Ross, D. T., Ciaravino, G., Sorlie, T., Troyanskaya, O., Diehn, M., Wang, Y. C., Duran, G. E., Sikic, T. L., Caldeira, S., Skomedal, H., Tu, I. - P., Hernandez-Boussard, T., Johnson, S. W., O'Dwyer, P. J., Fero, M. J., Kristensen, G. B., Borresen-Dale, A. - L., Hastie, T., Tibshirani, R., van de Rijn, M., Teng, N. N., Longacre, T. A., Botstein, D., Brown, P. O., and Sikic, B. I.,
“Gene expression patterns in ovarian carcinomas.”,
Mol Biol Cell, vol. 14, no. 11, pp. 4376-86, 2003.
Breast
M. van de Rijn, Perou, C. M., Tibshirani, R., Haas, P., Kallioniemi, O., Kononen, J., Torhorst, J., Sauter, G., Zuber, M., Köchli, O. R., Mross, F., Dieterich, H., Seitz, R., Ross, D., Botstein, D., and Brown, P.,
“Expression of cytokeratins 17 and 5 identifies a group of breast carcinomas with poor clinical outcome.”,
Am J Pathol, vol. 161, no. 6, pp. 1991-6, 2002.
Biological Markers
T. O. Nielsen, Hsu, F. D., O'Connell, J. X., C Gilks, B., Sorensen, P. H. B., Linn, S., West, R. B., Liu, C. Long, Botstein, D., Brown, P. O., and van de Rijn, M.,
“Tissue microarray validation of epidermal growth factor receptor and SALL2 in synovial sarcoma with comparison to tumors of similar histology.”,
Am J Pathol, vol. 163, no. 4, pp. 1449-56, 2003.
Animals
M. van de Rijn, Perou, C. M., Tibshirani, R., Haas, P., Kallioniemi, O., Kononen, J., Torhorst, J., Sauter, G., Zuber, M., Köchli, O. R., Mross, F., Dieterich, H., Seitz, R., Ross, D., Botstein, D., and Brown, P.,
“Expression of cytokeratins 17 and 5 identifies a group of breast carcinomas with poor clinical outcome.”,
Am J Pathol, vol. 161, no. 6, pp. 1991-6, 2002.
Aged
S. C. Linn, West, R. B., Pollack, J. R., Zhu, S., Hernandez-Boussard, T., Nielsen, T. O., Rubin, B. P., Patel, iv, R., Goldblum, J. R., Siegmund, D., Botstein, D., Brown, P. O., C Gilks, B., and van de Rijn, M.,
“Gene expression patterns and gene copy number changes in dermatofibrosarcoma protuberans.”,
Am J Pathol, vol. 163, no. 6, pp. 2383-95, 2003.
Adult
S. C. Linn, West, R. B., Pollack, J. R., Zhu, S., Hernandez-Boussard, T., Nielsen, T. O., Rubin, B. P., Patel, iv, R., Goldblum, J. R., Siegmund, D., Botstein, D., Brown, P. O., C Gilks, B., and van de Rijn, M.,
“Gene expression patterns and gene copy number changes in dermatofibrosarcoma protuberans.”,
Am J Pathol, vol. 163, no. 6, pp. 2383-95, 2003.
Adenocarcinoma, Clear Cell
M. E. Schaner, Ross, D. T., Ciaravino, G., Sorlie, T., Troyanskaya, O., Diehn, M., Wang, Y. C., Duran, G. E., Sikic, T. L., Caldeira, S., Skomedal, H., Tu, I. - P., Hernandez-Boussard, T., Johnson, S. W., O'Dwyer, P. J., Fero, M. J., Kristensen, G. B., Borresen-Dale, A. - L., Hastie, T., Tibshirani, R., van de Rijn, M., Teng, N. N., Longacre, T. A., Botstein, D., Brown, P. O., and Sikic, B. I.,
“Gene expression patterns in ovarian carcinomas.”,
Mol Biol Cell, vol. 14, no. 11, pp. 4376-86, 2003.
Adenocarcinoma
M. E. Schaner, Ross, D. T., Ciaravino, G., Sorlie, T., Troyanskaya, O., Diehn, M., Wang, Y. C., Duran, G. E., Sikic, T. L., Caldeira, S., Skomedal, H., Tu, I. - P., Hernandez-Boussard, T., Johnson, S. W., O'Dwyer, P. J., Fero, M. J., Kristensen, G. B., Borresen-Dale, A. - L., Hastie, T., Tibshirani, R., van de Rijn, M., Teng, N. N., Longacre, T. A., Botstein, D., Brown, P. O., and Sikic, B. I.,
“Gene expression patterns in ovarian carcinomas.”,
Mol Biol Cell, vol. 14, no. 11, pp. 4376-86, 2003.