List of Faculty Publications

Below is a list of Faculty publications imported from PubMed or manually added. By default, publications are sorted by year with titles displayed in ascending alphabetical order.
Shortcuts: Wühr, Martin | Wingreen, Ned | Wieschaus, Eric | Troyanskaya, Olga | Tilghman, Shirley | Storey, John | Singh, Mona | Shvartsman, Stanislav | Shaevitz, Joshua | Rabinowitz, Joshua | Murphy, Coleen | Levine, Michael {Levine, Michael S.} | Gregor, Thomas | Botstein, David | Bialek, William | Ayroles, Julien | Andolfatto, Peter | Akey, Joshua

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R. Dannenfelser, Nome, M., Tahiri, A., Ursini-Siegel, J., Vollan, H. Kristian M., Haakensen, V. D., Helland, Å., Naume, B., Caldas, C., Børresen-Dale, A. - L., Kristensen, V. N., and Troyanskaya, O. G., Data-driven analysis of immune infiltrate in a large cohort of breast cancer and its association with disease progression, ER activity, and genomic complexity., Oncotarget, vol. 8, no. 34, pp. 57121-57133, 2017.
P. F. Przytycki and Singh, M., Differential analysis between somatic mutation and germline variation profiles reveals cancer-related genes., Genome Med, vol. 9, no. 1, p. 79, 2017.
S. M. Davidson, Jonas, O., Keibler, M. A., Hou, H. Wei, Luengo, A., Mayers, J. R., Wyckoff, J., Del Rosario, A. M., Whitman, M., Chin, C. R., Condon, K. J., Lammers, A., Kellersberger, K. A., Stall, B. K., Stephanopoulos, G., Bar-Sagi, D., Han, J., Rabinowitz, J. D., Cima, M. J., Langer, R., and Heiden, M. G. Vander, Direct evidence for cancer-cell-autonomous extracellular protein catabolism in pancreatic tumors., Nat Med, vol. 23, no. 2, pp. 235-241, 2017.
S. Hong, Zhou, W., Fang, B., Lu, W., Loro, E., Damle, M., Ding, G., Jager, J., Zhang, S., Zhang, Y., Feng, D., Chu, Q., Dill, B. D., Molina, H., Khurana, T. S., Rabinowitz, J. D., Lazar, M. A., and Sun, Z., Dissociation of muscle insulin sensitivity from exercise endurance in mice by HDAC3 depletion., Nat Med, vol. 23, no. 2, pp. 223-234, 2017.
A. Ochoa and Singh, M., Domain prediction with probabilistic directional context., Bioinformatics, vol. 33, no. 16, pp. 2471-2478, 2017.
Y. Song, Marmion, R. A., Park, J. O., Biswas, D., Rabinowitz, J. D., and Shvartsman, S. Y., Dynamic Control of dNTP Synthesis in Early Embryos., Dev Cell, vol. 42, no. 3, pp. 301-308.e3, 2017.
N. Slavov and Botstein, D., Decoupling nutrient signaling from growth rate causes aerobic glycolysis and deregulation of cell size and gene expression., Mol Biol Cell, vol. 24, no. 2, pp. 157-68, 2013.
W. Ju, Greene, C. S., Eichinger, F., Nair, V., Hodgin, J. B., Bitzer, M., Lee, Y. -suk, Zhu, Q., Kehata, M., Li, M., Jiang, S., Rastaldi, M. Pia, Cohen, C. D., Troyanskaya, O. G., and Kretzler, M., Defining cell-type specificity at the transcriptional level in human disease., Genome Res, vol. 23, no. 11, pp. 1862-73, 2013.
J. Bothma and Levine, M., Development: lights, camera, action--the Drosophila embryo goes live!, Curr Biol, vol. 23, no. 21, pp. R965-7, 2013.
D. Ghersi and Singh, M., Disentangling function from topology to infer the network properties of disease genes., BMC Syst Biol, vol. 7, p. 5, 2013.
Y. - C. Wang, Khan, Z., and Wieschaus, E. F., Distinct Rap1 activity states control the extent of epithelial invagination via α-catenin., Dev Cell, vol. 25, no. 3, pp. 299-309, 2013.
F. Liu, Morrison, A. H., and Gregor, T., Dynamic interpretation of maternal inputs by the Drosophila segmentation gene network., Proc Natl Acad Sci U S A, vol. 110, no. 17, pp. 6724-9, 2013.
L. S. Cheung, Simakov, D. S. A., Fuchs, A., Pyrowolakis, G., and Shvartsman, S. Y., Dynamic model for the coordination of two enhancers of broad by EGFR signaling., Proc Natl Acad Sci U S A, vol. 110, no. 44, pp. 17939-44, 2013.
C. Huttenhower, K Mutungu, T., Indik, N., Yang, W., Schroeder, M., Forman, J. J., Troyanskaya, O. G., and Coller, H. A., Detailing regulatory networks through large scale data integration., Bioinformatics, vol. 25, no. 24, pp. 3267-74, 2009.
Y. Goltsev, Rezende, G. L., Vranizan, K., Lanzaro, G., Valle, D., and Levine, M., Developmental and evolutionary basis for drought tolerance of the Anopheles gambiae embryo., Dev Biol, vol. 330, no. 2, pp. 462-70, 2009.
W. Ndifon, Wingreen, N. S., and Levin, S. A., Differential neutralization efficiency of hemagglutinin epitopes, antibody interference, and the design of influenza vaccines., Proc Natl Acad Sci U S A, vol. 106, no. 21, pp. 8701-6, 2009.
G. Tkačik and Bialek, W., Diffusion, dimensionality, and noise in transcriptional regulation., Phys Rev E Stat Nonlin Soft Matter Phys, vol. 79, no. 5 Pt 1, p. 051901, 2009.
M. A. Hibbs, Myers, C. L., Huttenhower, C., Hess, D. C., Li, K., Caudy, A. A., and Troyanskaya, O. G., Directing experimental biology: a case study in mitochondrial biogenesis., PLoS Comput Biol, vol. 5, no. 3, p. e1000322, 2009.
C. L. Myers, Chiriac, C., and Troyanskaya, O. G., Discovering biological networks from diverse functional genomic data., Methods Mol Biol, vol. 563, pp. 157-75, 2009.
J. S. Kanodia, Rikhy, R., Kim, Y., Lund, V. K., DeLotto, R., Lippincott-Schwartz, J., and Shvartsman, S. Y., Dynamics of the Dorsal morphogen gradient., Proc Natl Acad Sci U S A, vol. 106, no. 51, pp. 21707-12, 2009.
L. R. Swem, Swem, D. L., Wingreen, N. S., and Bassler, B. L., Deducing receptor signaling parameters from in vivo analysis: LuxN/AI-1 quorum sensing in Vibrio harveyi., Cell, vol. 134, no. 3, pp. 461-73, 2008.
S. R. McAllister, Feng, X. - J., DiMaggio, P. A., Floudas, C. A., Rabinowitz, J. D., and Rabitz, H., Descriptor-free molecular discovery in large libraries by adaptive substituent reordering., Bioorg Med Chem Lett, vol. 18, no. 22, pp. 5967-70, 2008.
G. J. Stephens, Johnson-Kerner, B., Bialek, W., and Ryu, W. S., Dimensionality and dynamics in the behavior of C. elegans., PLoS Comput Biol, vol. 4, no. 4, p. e1000028, 2008.
J. D. Rabinowitz, Hsiao, J. J., Gryncel, K. R., Kantrowitz, E. R., Feng, X. - J., Li, G., and Rabitz, H., Dissecting enzyme regulation by multiple allosteric effectors: nucleotide regulation of aspartate transcarbamoylase., Biochemistry, vol. 47, no. 21, pp. 5881-8, 2008.
M. Piazza, Feng, X. - J., Rabinowitz, J. D., and Rabitz, H., Diverse metabolic model parameters generate similar methionine cycle dynamics., J Theor Biol, vol. 251, no. 4, pp. 628-39, 2008.
Y. Kyung Kwon, Lu, W., Melamud, E., Khanam, N., Bognar, A., and Rabinowitz, J. D., A domino effect in antifolate drug action in Escherichia coli., Nat Chem Biol, vol. 4, no. 10, pp. 602-8, 2008.
N. Yakoby, Lembong, J., Schüpbach, T., and Shvartsman, S. Y., Drosophila eggshell is patterned by sequential action of feedforward and feedback loops., Development, vol. 135, no. 2, pp. 343-51, 2008.
D. Papatsenko and Levine, M. S., Dual regulation by the Hunchback gradient in the Drosophila embryo., Proc Natl Acad Sci U S A, vol. 105, no. 8, pp. 2901-6, 2008.
S. Y. Shvartsman, Coppey, M., and Berezhkovskii, A. M., Dynamics of maternal morphogen gradients in Drosophila., Curr Opin Genet Dev, vol. 18, no. 4, pp. 342-7, 2008.
S. M. Tilghman, DNA methylation: a phoenix rises., Proc Natl Acad Sci U S A, vol. 90, no. 19, pp. 8761-2, 1993.