NetGrep: fast network schema searches in interactomes.

Publication Year
2008

Type

Journal Article
Abstract

NetGrep (http://genomics.princeton.edu/singhlab/netgrep/) is a system for searching protein interaction networks for matches to user-supplied 'network schemas'. Each schema consists of descriptions of proteins (for example, their molecular functions or putative domains) along with the desired topology and types of interactions among them. Schemas can thus describe domain-domain interactions, signaling and regulatory pathways, or more complex network patterns. NetGrep provides an advanced graphical interface for specifying schemas and fast algorithms for extracting their matches.

Journal
Genome Biol
Volume
9
Issue
9
Pages
R138
Alternate Journal
Genome Biol.