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Longevity

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  • Tepper, Ronald G, Jasmine M Ashraf, Rachel Kaletsky, Gunnar Kleemann, Coleen T Murphy, and Harmen J Bussemaker. (2013) 2013. “PQM-1 Complements DAF-16 As a Key Transcriptional Regulator of DAF-2-Mediated Development and Longevity.”. Cell 154 (3): 676-90.
    Reference Link
  • Shi, Cheng, and Coleen T Murphy. (2014) 2014. “Mating Induces Shrinking and Death in Caenorhabditis Mothers.”. Science 343 (6170): 536-40.
    Reference Link
  • Lee, Seung-Jae, Coleen T Murphy, and Cynthia Kenyon. (2009) 2009. “Glucose Shortens the Life Span of C. Elegans by Downregulating DAF-16 FOXO Activity and Aquaporin Gene Expression.”. Cell Metab 10 (5): 379-91.
    Reference Link
  • Murphy, Coleen T, Steven A McCarroll, Cornelia I Bargmann, Andrew Fraser, Ravi S Kamath, Julie Ahringer, Hao Li, and Cynthia Kenyon. (2003) 2003. “Genes That Act Downstream of DAF-16 to Influence the Lifespan of Caenorhabditis Elegans.”. Nature 424 (6946): 277-83.
    Reference Link
  • Rizki, Gizem, Terri Naoko Iwata, Ji Li, Christian G Riedel, Colette Lafontaine Picard, Max Jan, Coleen T Murphy, and Siu Sylvia Lee. (2011) 2011. “The Evolutionarily Conserved Longevity Determinants HCF-1 and SIR-2.1 SIRT1 Collaborate to Regulate DAF-16 FOXO.”. PLoS Genet 7 (9): e1002235.
    Reference Link
  • Tepper, Ronald G, Coleen T Murphy, and Harmen J Bussemaker. (2014) 2014. “DAF-16 and PQM-1: Partners in Longevity.”. Aging (Albany NY) 6 (1): 5-6.
    Reference Link
  • Oliveira, Riva P, Jess Porter Abate, Kieran Dilks, Jessica Landis, Jasmine M Ashraf, Coleen T Murphy, and Keith Blackwell. (2009) 2009. “Condition-Adapted Stress and Longevity Gene Regulation by Caenorhabditis Elegans SKN-1 Nrf.”. Aging Cell 8 (5): 524-41.
    Reference Link
  • Shaw, Wendy M, Shijing Luo, Jessica Landis, Jasmine M Ashraf, and Coleen T Murphy. (2007) 2007. “The C. Elegans TGF-Beta Dauer Pathway Regulates Longevity via Insulin Signaling.”. Curr Biol 17 (19): 1635-45.
    Reference Link
  • Murphy, Coleen T. (2010) 2010. “Aging: MiRacles of Longevity?”. Curr Biol 20 (24).
    Reference Link
  • Li, Siran, Howard A Stone, and Coleen T Murphy. (2015) 2015. “A Microfluidic Device and Automatic Counting System for the Study of C. Elegans Reproductive Aging.”. Lab Chip 15 (2): 524-31. doi:10.1039/c4lc01028k.
    Reference Link
  • Ewald, Collin Y, Jess N Landis, Jess Porter Abate, Coleen T Murphy, and Keith Blackwell. (2015) 2015. “Dauer-Independent Insulin IGF-1-Signalling Implicates Collagen Remodelling in Longevity.”. Nature 519 (7541): 97-101. doi:10.1038/nature14021.
    Reference Link
  • Murphy, Coleen T, Seung-Jae Lee, and Cynthia Kenyon. (2007) 2007. “Tissue Entrainment by Feedback Regulation of Insulin Gene Expression in the Endoderm of Caenorhabditis Elegans.”. Proc Natl Acad Sci U S A 104 (48): 19046-50.
    Reference Link
  • Hahm, Jeong-Hoon, Sunhee Kim, Race DiLoreto, Cheng Shi, Seung-Jae Lee V, Coleen T Murphy, and Hong Gil Nam. (2015) 2015. “C. Elegans Maximum Velocity Correlates With Healthspan and Is Maintained in Worms With an Insulin Receptor Mutation.”. Nat Commun 6: 8919. doi:10.1038/ncomms9919.
    Reference Link
  • Luo, Shijing, Wendy M Shaw, Jasmine M Ashraf, and Coleen T Murphy. (2009) 2009. “TGF-Beta Sma Mab Signaling Mutations Uncouple Reproductive Aging from Somatic Aging.”. PLoS Genet 5 (12): e1000789.
    Reference Link
  • Kaletsky, Rachel, Vanisha Lakhina, Rachel Arey, April Williams, Jessica Landis, Jasmine M Ashraf, and Coleen T Murphy. (2016) 2016. “The C. Elegans Adult Neuronal IIS FOXO Transcriptome Reveals Adult Phenotype Regulators.”. Nature 529 (7584): 92-6. doi:10.1038/nature16483.
    Reference Link
  • Murphy, Coleen T. (2006) 2006. “The Search for DAF-16 FOXO Transcriptional Targets: Approaches and Discoveries.”. Exp Gerontol 41 (10): 910-21.
    Reference Link
  • DiLoreto, Race, and Coleen T Murphy. (2015) 2015. “The Cell Biology of Aging.”. Mol Biol Cell 26 (25): 4524-31. doi:10.1091/mbc.E14-06-1084.
    Reference Link
  • Kaletsky, Rachel, and Coleen T Murphy. (2010) 2010. “The Role of Insulin IGF-Like Signaling in C. Elegans Longevity and Aging.”. Dis Model Mech 3 (7-8): 415-9.
    Reference Link
  • Hsu, Ao-Lin, Coleen T Murphy, and Cynthia Kenyon. (2003) 2003. “Regulation of Aging and Age-Related Disease by DAF-16 and Heat-Shock Factor.”. Science 300 (5622): 1142-5.
    Reference Link

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