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Insulin

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  • Leighton, P A, J R Saam, R S Ingram, C L Stewart, and S M Tilghman. (1995) 1995. “An Enhancer Deletion Affects Both H19 and Igf2 Expression.”. Genes Dev 9 (17): 2079-89.
    Reference Link
  • Leighton, P A, R S Ingram, J Eggenschwiler, A Efstratiadis, and S M Tilghman. (1995) 1995. “Disruption of Imprinting Caused by Deletion of the H19 Gene Region in Mice.”. Nature 375 (6526): 34-9.
    Reference Link
  • Shaw, Wendy M, Shijing Luo, Jessica Landis, Jasmine M Ashraf, and Coleen T Murphy. (2007) 2007. “The C. Elegans TGF-Beta Dauer Pathway Regulates Longevity via Insulin Signaling.”. Curr Biol 17 (19): 1635-45.
    Reference Link
  • Ewald, Collin Y, Jess N Landis, Jess Porter Abate, Coleen T Murphy, and Keith Blackwell. (2015) 2015. “Dauer-Independent Insulin IGF-1-Signalling Implicates Collagen Remodelling in Longevity.”. Nature 519 (7541): 97-101. doi:10.1038/nature14021.
    Reference Link
  • Hahm, Jeong-Hoon, Sunhee Kim, Race DiLoreto, Cheng Shi, Seung-Jae Lee V, Coleen T Murphy, and Hong Gil Nam. (2015) 2015. “C. Elegans Maximum Velocity Correlates With Healthspan and Is Maintained in Worms With an Insulin Receptor Mutation.”. Nat Commun 6: 8919. doi:10.1038/ncomms9919.
    Reference Link
  • Kaletsky, Rachel, Vanisha Lakhina, Rachel Arey, April Williams, Jessica Landis, Jasmine M Ashraf, and Coleen T Murphy. (2016) 2016. “The C. Elegans Adult Neuronal IIS FOXO Transcriptome Reveals Adult Phenotype Regulators.”. Nature 529 (7584): 92-6. doi:10.1038/nature16483.
    Reference Link
  • DiLoreto, Race, and Coleen T Murphy. (2015) 2015. “The Cell Biology of Aging.”. Mol Biol Cell 26 (25): 4524-31. doi:10.1091/mbc.E14-06-1084.
    Reference Link
  • Li, Ling-Bo, Haoyun Lei, Rachel Arey, Pengpeng Li, Jianfeng Liu, Coleen T Murphy, X Z Shawn Xu, and Kang Shen. (2016) 2016. “The Neuronal Kinesin UNC-104 KIF1A Is a Key Regulator of Synaptic Aging and Insulin Signaling-Regulated Memory.”. Curr Biol 26 (5): 605-15. doi:10.1016/j.cub.2015.12.068.
    Reference Link
  • Murphy, Coleen T, Seung-Jae Lee, and Cynthia Kenyon. (2007) 2007. “Tissue Entrainment by Feedback Regulation of Insulin Gene Expression in the Endoderm of Caenorhabditis Elegans.”. Proc Natl Acad Sci U S A 104 (48): 19046-50.
    Reference Link
  • Luo, Shijing, Gunnar A Kleemann, Jasmine M Ashraf, Wendy M Shaw, and Coleen T Murphy. (2010) 2010. “TGF-β and Insulin Signaling Regulate Reproductive Aging via Oocyte and Germline Quality Maintenance.”. Cell 143 (2): 299-312.
    Reference Link
  • Murphy, Coleen T. (2006) 2006. “The Search for DAF-16 FOXO Transcriptional Targets: Approaches and Discoveries.”. Exp Gerontol 41 (10): 910-21.
    Reference Link
  • Kaletsky, Rachel, and Coleen T Murphy. (2010) 2010. “The Role of Insulin IGF-Like Signaling in C. Elegans Longevity and Aging.”. Dis Model Mech 3 (7-8): 415-9.
    Reference Link
  • Hsu, Ao-Lin, Coleen T Murphy, and Cynthia Kenyon. (2003) 2003. “Regulation of Aging and Age-Related Disease by DAF-16 and Heat-Shock Factor.”. Science 300 (5622): 1142-5.
    Reference Link
  • Kauffman, Amanda L, Jasmine M Ashraf, Ryan Corces-Zimmerman, Jessica N Landis, and Coleen T Murphy. (2010) 2010. “Insulin Signaling and Dietary Restriction Differentially Influence the Decline of Learning and Memory With Age.”. PLoS Biol 8 (5): e1000372.
    Reference Link
  • Lee, Seung-Jae, Coleen T Murphy, and Cynthia Kenyon. (2009) 2009. “Glucose Shortens the Life Span of C. Elegans by Downregulating DAF-16 FOXO Activity and Aquaporin Gene Expression.”. Cell Metab 10 (5): 379-91.
    Reference Link
  • Murphy, Coleen T, Steven A McCarroll, Cornelia I Bargmann, Andrew Fraser, Ravi S Kamath, Julie Ahringer, Hao Li, and Cynthia Kenyon. (2003) 2003. “Genes That Act Downstream of DAF-16 to Influence the Lifespan of Caenorhabditis Elegans.”. Nature 424 (6946): 277-83.
    Reference Link

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