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Gene Expression Profiling

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  • Guan, Yuanfang, Maitreya Dunham, Amy A Caudy, and Olga Troyanskaya. (2010) 2010. “Systematic Planning of Genome-Scale Experiments in Poorly Studied Species.”. PLoS Comput Biol 6 (3): e1000698.
    Reference Link
  • Greene, Casey S, and Olga G Troyanskaya. (2011) 2011. “PILGRM: An Interactive Data-Driven Discovery Platform for Expert Biologists.”. Nucleic Acids Res 39 (Web Server issue).
    Reference Link
  • Kristensen, Vessela N, Charles J Vaske, Josie Ursini-Siegel, Peter Van Loo, Silje H Nordgard, Ravi Sachidanandam, Therese Sørlie, et al. (2012) 2012. “Integrated Molecular Profiles of Invasive Breast Tumors and Ductal Carcinoma in Situ (DCIS) Reveal Differential Vascular and Interleukin Signaling.”. Proc Natl Acad Sci U S A 109 (8): 2802-7.
    Reference Link
  • Sørlie, Therese, Charles M Perou, Cheng Fan, Stephanie Geisler, Turid Aas, Andrew Nobel, Gun Anker, et al. (2006) 2006. “Gene Expression Profiles Do Not Consistently Predict the Clinical Treatment Response in Locally Advanced Breast Cancer.”. Mol Cancer Ther 5 (11): 2914-8.
    Reference Link
  • Goltsev, Yury, Gustavo L Rezende, Karen Vranizan, Greg Lanzaro, Denise Valle, and Michael Levine. (2009) 2009. “Developmental and Evolutionary Basis for Drought Tolerance of the Anopheles Gambiae Embryo.”. Dev Biol 330 (2): 462-70.
    Reference Link
  • Rangan, Aaditya, V, Caroline C McGrouther, John Kelsoe, Nicholas Schork, Eli Stahl, Qian Zhu, Arjun Krishnan, et al. (2018) 2018. “A Loop-Counting Method for Covariate-Corrected Low-Rank Biclustering of Gene-Expression and Genome-Wide Association Study Data.”. PLoS Comput Biol 14 (5): e1006105. doi:10.1371/journal.pcbi.1006105.
    Reference Link
  • Wang, Wei, Michael Cherry, David Botstein, and Hao Li. (2002) 2002. “A Systematic Approach to Reconstructing Transcription Networks in Saccharomycescerevisiae.”. Proc Natl Acad Sci U S A 99 (26): 16893-8.
    Reference Link
  • Leung, Suet Y, Xin Chen, Kent M Chu, Siu T Yuen, Jonathan Mathy, Jiafu Ji, Annie S Y Chan, et al. (2002) 2002. “Phospholipase A2 Group IIA Expression in Gastric Adenocarcinoma Is Associated With Prolonged Survival and Less Frequent Metastasis.”. Proc Natl Acad Sci U S A 99 (25): 16203-8.
    Reference Link
  • Troyanskaya, Olga G. 2007. “Integrated Analysis of Microarray Results.”. Methods Mol Biol 382: 429-37.
    Reference Link
  • Linn, Sabine C, Rob B West, Jonathan R Pollack, Shirley Zhu, Tina Hernandez-Boussard, Torsten O Nielsen, Brian P Rubin, et al. (2003) 2003. “Gene Expression Patterns and Gene Copy Number Changes in Dermatofibrosarcoma Protuberans.”. Am J Pathol 163 (6): 2383-95.
    Reference Link
  • Huttenhower, Curtis, Tsheko Mutungu, Natasha Indik, Woongcheol Yang, Mark Schroeder, Joshua J Forman, Olga G Troyanskaya, and Hilary A Coller. (2009) 2009. “Detailing Regulatory Networks through Large Scale Data Integration.”. Bioinformatics 25 (24): 3267-74.
    Reference Link
  • Menon, Rajasree, Edgar A Otto, Austin Kokoruda, Jian Zhou, Zidong Zhang, Euisik Yoon, Yu-Chih Chen, et al. (2018) 2018. “Single-Cell Analysis of Progenitor Cell Dynamics and Lineage Specification in the Human Fetal Kidney.”. Development 145 (16). doi:10.1242/dev.164038.
    Reference Link
  • Boldrick, Jennifer C, Ash A Alizadeh, Maximilian Diehn, Sandrine Dudoit, Chih Long Liu, Christopher E Belcher, David Botstein, Louis M Staudt, Patrick O Brown, and David A Relman. (2002) 2002. “Stereotyped and Specific Gene Expression Programs in Human Innate Immune Responses to Bacteria.”. Proc Natl Acad Sci U S A 99 (2): 972-7.
    Reference Link
  • Lee, Young-suk, Arjun Krishnan, Qian Zhu, and Olga G Troyanskaya. (2013) 2013. “Ontology-Aware Classification of Tissue and Cell-Type Signals in Gene Expression Profiles across Platforms and Technologies.”. Bioinformatics 29 (23): 3036-44.
    Reference Link
  • Slonim, Noam, Gurinder Singh Atwal, Gašper Tkačik, and William Bialek. (2005) 2005. “Information-Based Clustering.”. Proc Natl Acad Sci U S A 102 (51): 18297-302.
    Reference Link
  • Ayroles, Julien, Brooke A Laflamme, Eric A Stone, Mariana F Wolfner, and Trudy F C Mackay. (2011) 2011. “Functional Genome Annotation of Drosophila Seminal Fluid Proteins Using Transcriptional Genetic Networks.”. Genet Res (Camb) 93 (6): 387-95.
    Reference Link
  • Ju, Wenjun, Casey S Greene, Felix Eichinger, Viji Nair, Jeffrey B Hodgin, Markus Bitzer, Young-suk Lee, et al. (2013) 2013. “Defining Cell-Type Specificity at the Transcriptional Level in Human Disease.”. Genome Res 23 (11): 1862-73.
    Reference Link
  • Zhou, Jian, Ignacio E Schor, Victoria Yao, Chandra L Theesfeld, Raquel Marco-Ferreres, Alicja Tadych, Eileen E M Furlong, and Olga G Troyanskaya. (2019) 2019. “Accurate Genome-Wide Predictions of Spatio-Temporal Gene Expression During Embryonic Development.”. PLoS Genet 15 (9): e1008382. doi:10.1371/journal.pgen.1008382.
    Reference Link
  • Gibney, Patrick A, Charles Lu, Amy A Caudy, David C Hess, and David Botstein. (2013) 2013. “Yeast Metabolic and Signaling Genes Are Required for Heat-Shock Survival and Have Little Overlap With the Heat-Induced Genes.”. Proc Natl Acad Sci U S A 110 (46).
    Reference Link
  • Gollub, Jeremy, Catherine A Ball, Gail Binkley, Janos Demeter, David B Finkelstein, Joan M Hebert, Tina Hernandez-Boussard, et al. (2003) 2003. “The Stanford Microarray Database: Data Access and Quality Assessment Tools.”. Nucleic Acids Res 31 (1): 94-6.
    Reference Link
  • Saldanha, Alok J, Matthew J Brauer, and David Botstein. (2004) 2004. “Nutritional Homeostasis in Batch and Steady-State Culture of Yeast.”. Mol Biol Cell 15 (9): 4089-104.
    Reference Link
  • Wang, Wei, Michael Cherry, Yigal Nochomovitz, Emmitt Jolly, David Botstein, and Hao Li. (2005) 2005. “Inference of Combinatorial Regulation in Yeast Transcriptional Networks: A Case Study of Sporulation.”. Proc Natl Acad Sci U S A 102 (6): 1998-2003.
    Reference Link
  • McIsaac, Scott, Sanford J Silverman, Megan N McClean, Patrick A Gibney, Joanna Macinskas, Mark J Hickman, Allegra A Petti, and David Botstein. (2011) 2011. “Fast-Acting and Nearly Gratuitous Induction of Gene Expression and Protein Depletion in Saccharomyces Cerevisiae.”. Mol Biol Cell 22 (22): 4447-59.
    Reference Link
  • Hickman, Mark J, Allegra A Petti, Olivia Ho-Shing, Sanford J Silverman, Scott McIsaac, Traci A Lee, and David Botstein. (2011) 2011. “Coordinated Regulation of Sulfur and Phospholipid Metabolism Reflects the Importance of Methylation in the Growth of Yeast.”. Mol Biol Cell 22 (21): 4192-204.
    Reference Link
  • Klosinska, Maja M, Christopher A Crutchfield, Patrick H Bradley, Joshua D Rabinowitz, and James R Broach. (2011) 2011. “Yeast Cells Can Access Distinct Quiescent States.”. Genes Dev 25 (4): 336-49.
    Reference Link
  • Diehn, Maximilian, Gavin Sherlock, Gail Binkley, Heng Jin, John C Matese, Tina Hernandez-Boussard, Christian A Rees, et al. (2003) 2003. “SOURCE: A Unified Genomic Resource of Functional Annotations, Ontologies, and Gene Expression Data.”. Nucleic Acids Res 31 (1): 219-23.
    Reference Link
  • Troyanskaya, Olga G, Mitchell E Garber, Patrick O Brown, David Botstein, and Russ B Altman. (2002) 2002. “Nonparametric Methods for Identifying Differentially Expressed Genes in Microarray Data.”. Bioinformatics 18 (11): 1454-61.
    Reference Link
  • Kocher, Sarah D, Julien Ayroles, Eric A Stone, and Christina M Grozinger. 2010. “Individual Variation in Pheromone Response Correlates With Reproductive Traits and Brain Gene Expression in Worker Honey Bees.”. PLoS One 5 (2): e9116.
    Reference Link
  • Jeffrey, Stefanie S, Michael J Fero, Anne-Lise Børresen-Dale, and David Botstein. (2002) 2002. “Expression Array Technology in the Diagnosis and Treatment of Breast Cancer.”. Mol Interv 2 (2): 101-9.
    Reference Link
  • Bradley, Patrick H, Matthew J Brauer, Joshua D Rabinowitz, and Olga G Troyanskaya. (2009) 2009. “Coordinated Concentration Changes of Transcripts and Metabolites in Saccharomyces Cerevisiae.”. PLoS Comput Biol 5 (1): e1000270.
    Reference Link
  • Stathopoulos, Angelike, and Michael Levine. (2002) 2002. “Whole-Genome Expression Profiles Identify Gene Batteries in Drosophila.”. Dev Cell 3 (4): 464-5.
    Reference Link
  • Huttenhower, Curtis, Matt Hibbs, Chad Myers, and Olga G Troyanskaya. (2006) 2006. “A Scalable Method for Integration and Functional Analysis of Multiple Microarray Datasets.”. Bioinformatics 22 (23): 2890-7.
    Reference Link
  • Caudy, Amy A, Yuanfang Guan, Yue Jia, Christina Hansen, Chris DeSevo, Alicia P Hayes, Joy Agee, et al. (2013) 2013. “A New System for Comparative Functional Genomics of Saccharomyces Yeasts.”. Genetics 195 (1): 275-87.
    Reference Link
  • Marstrand, Troels T, and John D Storey. (2014) 2014. “Identifying and Mapping Cell-Type-Specific Chromatin Programming of Gene Expression.”. Proc Natl Acad Sci U S A 111 (6).
    Reference Link
  • Huttenhower, Curtis, Erin M Haley, Matthew A Hibbs, Vanessa Dumeaux, Daniel R Barrett, Hilary A Coller, and Olga G Troyanskaya. (2009) 2009. “Exploring the Human Genome With Functional Maps.”. Genome Res 19 (6): 1093-106.
    Reference Link
  • Slavov, Nikolai, Edoardo M Airoldi, Alexander van Oudenaarden, and David Botstein. (2012) 2012. “A Conserved Cell Growth Cycle Can Account for the Environmental Stress Responses of Divergent Eukaryotes.”. Mol Biol Cell 23 (10): 1986-97.
    Reference Link
  • Myers, Chad L, Xing Chen, and Olga G Troyanskaya. 2005. “Visualization-Based Discovery and Analysis of Genomic Aberrations in Microarray Data.”. BMC Bioinformatics 6: 146.
    Reference Link
  • Tkačik, Gašper, Thomas Gregor, and William Bialek. 2008. “The Role of Input Noise in Transcriptional Regulation.”. PLoS One 3 (7): e2774.
    Reference Link
  • Markowetz, Florian, Dennis Kostka, Olga G Troyanskaya, and Rainer Spang. (2007) 2007. “Nested Effects Models for High-Dimensional Phenotyping Screens.”. Bioinformatics 23 (13).
    Reference Link
  • Abitua, Philip Barron, Eileen Wagner, Ignacio A Navarrete, and Michael Levine. (2012) 2012. “Identification of a Rudimentary Neural Crest in a Non-Vertebrate Chordate.”. Nature 492 (7427): 104-7.
    Reference Link
  • Hibbs, Matthew A, David C Hess, Chad L Myers, Curtis Huttenhower, Kai Li, and Olga G Troyanskaya. (2007) 2007. “Exploring the Functional Landscape of Gene Expression: Directed Search of Large Microarray Compendia.”. Bioinformatics 23 (20): 2692-9.
    Reference Link
  • McCarroll, Steven A, Coleen T Murphy, Sige Zou, Scott D Pletcher, Chen-Shan Chin, Yuh Nung Jan, Cynthia Kenyon, Cornelia I Bargmann, and Hao Li. (2004) 2004. “Comparing Genomic Expression Patterns across Species Identifies Shared Transcriptional Profile in Aging.”. Nat Genet 36 (2): 197-204.
    Reference Link
  • Hibbs, Matthew A, Nathaniel C Dirksen, Kai Li, and Olga G Troyanskaya. 2005. “Visualization Methods for Statistical Analysis of Microarray Clusters.”. BMC Bioinformatics 6: 115.
    Reference Link
  • Trinklein, Nathan D, John I Murray, Sara J Hartman, David Botstein, and Richard M Myers. (2004) 2004. “The Role of Heat Shock Transcription Factor 1 in the Genome-Wide Regulation of the Mammalian Heat Shock Response.”. Mol Biol Cell 15 (3): 1254-61.
    Reference Link
  • Huttenhower, Curtis, Avi I Flamholz, Jessica N Landis, Sauhard Sahi, Chad L Myers, Kellen L Olszewski, Matthew A Hibbs, Nathan O Siemers, Olga G Troyanskaya, and Hilary A Coller. 2007. “Nearest Neighbor Networks: Clustering Expression Data Based on Gene Neighborhoods.”. BMC Bioinformatics 8: 250.
    Reference Link
  • Brauer, Matthew J, Alok J Saldanha, Kara Dolinski, and David Botstein. (2005) 2005. “Homeostatic Adjustment and Metabolic Remodeling in Glucose-Limited Yeast Cultures.”. Mol Biol Cell 16 (5): 2503-17.
    Reference Link
  • Wyart, Matthieu, David Botstein, and Ned S Wingreen. 2010. “Evaluating Gene Expression Dynamics Using Pairwise RNA FISH Data.”. PLoS Comput Biol 6 (11): e1000979.
    Reference Link
  • Guan, Yuanfang, Maitreya Dunham, Olga G Troyanskaya, and Amy A Caudy. 2013. “Comparative Gene Expression Between Two Yeast Species.”. BMC Genomics 14: 33.
    Reference Link
  • Chen, Xin, Suet Y Leung, Siu T Yuen, Kent-Man Chu, Jiafu Ji, Rui Li, Annie S Y Chan, et al. (2003) 2003. “Variation in Gene Expression Patterns in Human Gastric Cancers.”. Mol Biol Cell 14 (8): 3208-15.
    Reference Link
  • Gresham, David, Michael M Desai, Cheryl M Tucker, Harry T Jenq, Dave A Pai, Alexandra Ward, Christopher G DeSevo, David Botstein, and Maitreya Dunham. (2008) 2008. “The Repertoire and Dynamics of Evolutionary Adaptations to Controlled Nutrient-Limited Environments in Yeast.”. PLoS Genet 4 (12): e1000303.
    Reference Link

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