Dynamics of maternal morphogen gradients in Drosophila.

Publication Year
2008

Type

Journal Article
Abstract

The first direct studies of morphogen gradients were done in the end of 1980s, in the early Drosophila embryo, which is patterned under the action of four maternally determined morphogens. Since the early studies of maternal morphogens were done with fixed embryos, they were viewed as relatively static signals. Several recent studies analyze dynamics of the anterior, dorsoventral, and terminal patterning signals. The results of these quantitative studies provide critical tests of classical models and reveal new modes of morphogen regulation and readout in one of the most extensively studied patterning systems.

Journal
Curr Opin Genet Dev
Volume
18
Issue
4
Pages
342-7
Date Published
08/2008
Alternate Journal
Curr. Opin. Genet. Dev.