Lu, Wenyun, Bryson D Bennett, and Joshua D Rabinowitz. (2008) 2008. “Analytical Strategies for LC-MS-Based Targeted Metabolomics.”. J Chromatogr B Analyt Technol Biomed Life Sci 871 (2): 236-42. Reference Link
Hui, Sheng, Jonathan M Ghergurovich, Raphael J Morscher, Cholsoon Jang, Xin Teng, Wenyun Lu, Lourdes A Esparza, et al. (2017) 2017. “Glucose Feeds the TCA Cycle via Circulating Lactate.”. Nature 551 (7678): 115-18. doi:10.1038/nature24057. Reference Link
Kelly, Robert C, Megan E Bolitho, Douglas A Higgins, Wenyun Lu, Wai-Leung Ng, Philip D Jeffrey, Joshua D Rabinowitz, Martin F Semmelhack, Frederick M Hughson, and Bonnie L Bassler. (2009) 2009. “The Vibrio Cholerae Quorum-Sensing Autoinducer CAI-1: Analysis of the Biosynthetic Enzyme CqsA.”. Nat Chem Biol 5 (12): 891-5. Reference Link
Hess, David C, Wenyun Lu, Joshua D Rabinowitz, and David Botstein. (2006) 2006. “Ammonium Toxicity and Potassium Limitation in Yeast.”. PLoS Biol 4 (11): e351. Reference Link
Jang, Cholsoon, Sheng Hui, Wenyun Lu, Alexis J Cowan, Raphael J Morscher, Gina Lee, Wei Liu, Gregory J Tesz, Morris J Birnbaum, and Joshua D Rabinowitz. (2018) 2018. “The Small Intestine Converts Dietary Fructose into Glucose and Organic Acids.”. Cell Metab 27 (2): 351-361.e3. doi:10.1016/j.cmet.2017.12.016. Reference Link
Bajad, Sunil U, Wenyun Lu, Elizabeth H Kimball, Jie Yuan, Celeste Peterson, and Joshua D Rabinowitz. (2006) 2006. “Separation and Quantitation of Water Soluble Cellular Metabolites by Hydrophilic Interaction Chromatography-Tandem Mass Spectrometry.”. J Chromatogr A 1125 (1): 76-88. Reference Link
Teng, Shu-Wen, Jessica N Schaffer, Kimberly C Tu, Pankaj Mehta, Wenyun Lu, N P Ong, Bonnie L Bassler, and Ned S Wingreen. (2011) 2011. “Active Regulation of Receptor Ratios Controls Integration of Quorum-Sensing Signals in Vibrio Harveyi.”. Mol Syst Biol 7: 491. Reference Link
Miller, Russell A, Yuji Shi, Wenyun Lu, David A Pirman, Aditi Jatkar, Matthew Blatnik, Hong Wu, et al. (2018) 2018. “Targeting Hepatic Glutaminase Activity to Ameliorate Hyperglycemia.”. Nat Med 24 (4): 518-24. doi:10.1038/nm.4514. Reference Link
Waters, Christopher M, Wenyun Lu, Joshua D Rabinowitz, and Bonnie L Bassler. (2008) 2008. “Quorum Sensing Controls Biofilm Formation in Vibrio Cholerae through Modulation of Cyclic Di-GMP Levels and Repression of VpsT.”. J Bacteriol 190 (7): 2527-36. Reference Link
Titchenell, Paul M, William J Quinn, Mingjian Lu, Qingwei Chu, Wenyun Lu, Changhong Li, Helen Chen, et al. 2016. “Direct Hepatocyte Insulin Signaling Is Required for Lipogenesis But Is Dispensable for the Suppression of Glucose Production.”. Cell Metab. doi:10.1016/j.cmet.2016.04.022. Reference Link
Xu, Yi-Fan, Wenyun Lu, Jonathan C Chen, Sarah A Johnson, Patrick A Gibney, David G Thomas, Greg Brown, et al. (2018) 2018. “Discovery and Functional Characterization of a Yeast Sugar Alcohol Phosphatase.”. ACS Chem Biol 13 (10): 3011-20. doi:10.1021/acschembio.8b00804. Reference Link
Xu, Yi-Fan, Fabien Létisse, Farnaz Absalan, Wenyun Lu, Ekaterina Kuznetsova, Greg Brown, Amy A Caudy, Alexander F Yakunin, James R Broach, and Joshua D Rabinowitz. 2013. “Nucleotide Degradation and Ribose Salvage in Yeast.”. Mol Syst Biol 9: 665. Reference Link
Bott, Alex J, I-Chen Peng, Yongjun Fan, Brandon Faubert, Lu Zhao, Jinyu Li, Sarah Neidler, et al. (2015) 2015. “Oncogenic Myc Induces Expression of Glutamine Synthetase through Promoter Demethylation.”. Cell Metab 22 (6): 1068-77. Reference Link
Poillet-Perez, Laura, Xiaoqi Xie, Le Zhan, Yang Yang, Daniel W Sharp, Zhixian Sherrie Hu, Xiaoyang Su, et al. (2018) 2018. “Autophagy Maintains Tumour Growth through Circulating Arginine.”. Nature 563 (7732): 569-73. doi:10.1038/s41586-018-0697-7. Reference Link
Lu, Wenyun, Michelle F Clasquin, Eugene Melamud, Daniel Amador-Noguez, Amy A Caudy, and Joshua D Rabinowitz. (2010) 2010. “Metabolomic Analysis via Reversed-Phase Ion-Pairing Liquid Chromatography Coupled to a Stand Alone Orbitrap Mass Spectrometer.”. Anal Chem 82 (8): 3212-21. Reference Link
Koivunen, Peppi, Stuart M Fell, Wenyun Lu, Joshua D Rabinowitz, Andrew L Kung, and Susanne Schlisio. 2016. “The 2-Oxoglutarate Analog 3-Oxoglutarate Decreases Normoxic Hypoxia-Inducible Factor-1α in Cancer Cells, Induces Cell Death, and Reduces Tumor Xenograft Growth.”. Hypoxia (Auckl) 4: 15-27. doi:10.2147/HP.S96366. Reference Link
Wang, Lin, Xi Xing, Li Chen, Lifeng Yang, Xiaoyang Su, Herschel Rabitz, Wenyun Lu, and Joshua D Rabinowitz. (2019) 2019. “Peak Annotation and Verification Engine for Untargeted LC-MS Metabolomics.”. Anal Chem 91 (3): 1838-46. doi:10.1021/acs.analchem.8b03132. Reference Link
Crutchfield, Christopher A, Wenyun Lu, Eugene Melamud, and Joshua D Rabinowitz. 2010. “Mass Spectrometry-Based Metabolomics of Yeast.”. Methods Enzymol 470: 393-426. Reference Link
Papazyan, Romeo, Zheng Sun, Yong Hoon Kim, Paul M Titchenell, David A Hill, Wenyun Lu, Manashree Damle, et al. (2016) 2016. “Physiological Suppression of Lipotoxic Liver Damage by Complementary Actions of HDAC3 and SCAP SREBP.”. Cell Metab 24 (6): 863-74. doi:10.1016/j.cmet.2016.10.012. Reference Link
Gokhale, Samantha, Wenyun Lu, Sining Zhu, Yingying Liu, Ronald P Hart, Joshua D Rabinowitz, and Ping Xie. (2020) 2020. “Elevated Choline Kinase α-Mediated Choline Metabolism Supports the Prolonged Survival of TRAF3-Deficient B Lymphocytes.”. J Immunol 204 (2): 459-71. doi:10.4049/jimmunol.1900658. Reference Link
Kamphorst, Jurre J, Jing Fan, Wenyun Lu, Eileen White, and Joshua D Rabinowitz. (2011) 2011. “Liquid Chromatography-High Resolution Mass Spectrometry Analysis of Fatty Acid Metabolism.”. Anal Chem 83 (23): 9114-22. Reference Link
Hong, Sungguan, Wenjun Zhou, Bin Fang, Wenyun Lu, Emanuele Loro, Manashree Damle, Guolian Ding, et al. (2017) 2017. “Dissociation of Muscle Insulin Sensitivity from Exercise Endurance in Mice by HDAC3 Depletion.”. Nat Med 23 (2): 223-34. doi:10.1038/nm.4245. Reference Link
Yang, Lifeng, Tara TeSlaa, Serina Ng, Michel Nofal, Lin Wang, Taijin Lan, Xianfeng Zeng, et al. (2022) 2022. “Ketogenic Diet and Chemotherapy Combine to Disrupt Pancreatic Cancer Metabolism and Growth.”. Med (N Y) 3 (2): 119-36. doi:10.1016/j.medj.2021.12.008. Reference Link
Yuan, Jie, William U Fowler, Elizabeth Kimball, Wenyun Lu, and Joshua D Rabinowitz. (2006) 2006. “Kinetic Flux Profiling of Nitrogen Assimilation in Escherichia Coli.”. Nat Chem Biol 2 (10): 529-30. Reference Link
Su, Xiaoyang, Wenyun Lu, and Joshua D Rabinowitz. (2017) 2017. “Metabolite Spectral Accuracy on Orbitraps.”. Anal Chem 89 (11): 5940-48. doi:10.1021/acs.analchem.7b00396. Reference Link
Lu, Wenyun, Yun Kyung Kwon, and Joshua D Rabinowitz. (2007) 2007. “Isotope Ratio-Based Profiling of Microbial Folates.”. J Am Soc Mass Spectrom 18 (5): 898-909. Reference Link
Lu, Wenyun, Lin Wang, Li Chen, Sheng Hui, and Joshua D Rabinowitz. (2017) 2017. “Extraction and Quantitation of Nicotinamide Adenine Dinucleotide Redox Cofactors.”. Antioxid Redox Signal. doi:10.1089/ars.2017.7014. Reference Link
Kamphorst, Jurre J, Michel Nofal, Cosimo Commisso, Sean R Hackett, Wenyun Lu, Elda Grabocka, Matthew G Vander Heiden, et al. (2015) 2015. “Human Pancreatic Cancer Tumors Are Nutrient Poor and Tumor Cells Actively Scavenge Extracellular Protein.”. Cancer Res 75 (3): 544-53. Reference Link
Gong, Yingyun, Rui Cao, Guolian Ding, Sungguan Hong, Wenjun Zhou, Wenyun Lu, Manashree Damle, et al. (2017) 2017. “Integrated Omics Approaches to Characterize a Nuclear Receptor Corepressor-Associated Histone Deacetylase in Mouse Skeletal Muscle.”. Mol Cell Endocrinol. doi:10.1016/j.mce.2017.05.024. Reference Link
Lu, Wenyun, Elizabeth Kimball, and Joshua D Rabinowitz. (2006) 2006. “A High-Performance Liquid Chromatography-Tandem Mass Spectrometry Method for Quantitation of Nitrogen-Containing Intracellular Metabolites.”. J Am Soc Mass Spectrom 17 (1): 37-50. Reference Link
Lu, Wenyun, Xiaoyang Su, Matthias S Klein, Ian A Lewis, Oliver Fiehn, and Joshua D Rabinowitz. (2017) 2017. “Metabolite Measurement: Pitfalls to Avoid and Practices to Follow.”. Annu Rev Biochem 86: 277-304. doi:10.1146/annurev-biochem-061516-044952. Reference Link
Kwon, Yun Kyung, Wenyun Lu, Eugene Melamud, Nurussaba Khanam, Andrew Bognar, and Joshua D Rabinowitz. (2008) 2008. “A Domino Effect in Antifolate Drug Action in Escherichia Coli.”. Nat Chem Biol 4 (10): 602-8. Reference Link
Chen, Li, Gregory S Ducker, Wenyun Lu, Xin Teng, and Joshua D Rabinowitz. (2017) 2017. “An LC-MS Chemical Derivatization Method for the Measurement of Five Different One-Carbon States of Cellular Tetrahydrofolate.”. Anal Bioanal Chem. doi:10.1007/s00216-017-0514-4. Reference Link
Brauer, Matthew J, Jie Yuan, Bryson D Bennett, Wenyun Lu, Elizabeth Kimball, David Botstein, and Joshua D Rabinowitz. (2006) 2006. “Conservation of the Metabolomic Response to Starvation across Two Divergent Microbes.”. Proc Natl Acad Sci U S A 103 (51): 19302-7. Reference Link
Kim, Hye In, Johannes Raffler, Wenyun Lu, Jung-Jin Lee, Deepti Abbey, Danish Saleheen, Joshua D Rabinowitz, et al. (2017) 2017. “Fine Mapping and Functional Analysis Reveal a Role of SLC22A1 in Acylcarnitine Transport.”. Am J Hum Genet 101 (4): 489-502. doi:10.1016/j.ajhg.2017.08.008. Reference Link
Bao, Qing, Wenyun Lu, Joshua D Rabinowitz, and Yigong Shi. (2007) 2007. “Calcium Blocks Formation of Apoptosome by Preventing Nucleotide Exchange in Apaf-1.”. Mol Cell 25 (2): 181-92. Reference Link
Liu, Laura X, Glenn C Rowe, Steven Yang, Jian Li, Federico Damilano, Mun Chun Chan, Wenyun Lu, et al. (2017) 2017. “PDK4 Inhibits Cardiac Pyruvate Oxidation in Late Pregnancy.”. Circ Res. doi:10.1161/CIRCRESAHA.117.311456. Reference Link
Xu, Yi-Fan, Wenyun Lu, and Joshua D Rabinowitz. (2015) 2015. “Avoiding Misannotation of in-Source Fragmentation Products As Cellular Metabolites in Liquid Chromatography-Mass Spectrometry-Based Metabolomics.”. Anal Chem 87 (4): 2273-81. Reference Link
Wooldridge, Amy L, Robert J Bischof, Hong Liu, Gary K Heinemann, Damien S Hunter, Lynne C Giles, Rebecca A Simmons, et al. (2017) 2017. “Late Gestation Maternal Dietary Methyl Donor and Cofactor Supplementation in Sheep Partially Reverses Protection Against Allergic Sensitization by IUGR.”. Am J Physiol Regul Integr Comp Physiol, ajpregu.00549.2016. doi:10.1152/ajpregu.00549.2016. Reference Link