April 1, 2019

Identifying a patient’s viral infection or diagnosing a blood disorder usually requires a lab and skilled technicians. But Princeton researchers including Haw Yang, professor of chemistry,and Kaushik Sengupta, assistant professor of electrical engineering, have developed a new technology that goes a long way toward replacing the lab with a single microchip.

In an important step toward performing medical diagnoses using handheld devices, the researchers have adapted silicon chip technology similar to that found in personal computers and mobile phones to function as a biosensor. The technology uses tiny metal layers embedded in a microchip to eliminate all complex and bulky optical instrumentation employed in the diagnostic labs. As a result, the new system is almost as small as a grain of salt, and far less costly to manufacture than current diagnostic systems.

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Story by Bennett McIntosh for the School of Engineering and Applied Science