March 11, 2019

story by Catherine Zandonella, Office of the Dean for Research

Now a team from Princeton, including Andreas Mayer, Ned Wingreen and Yaojun Zhang, has provided insight into this question using mathematical modeling. The team found that the most important factors in how T cells expand were the starting amount of infectious agent and the affinity of the cells for that agent. The research, which could help optimize vaccine strategies, was published last week in the journal Proceedings of the National Academy of Sciences.

Full story here.