TitleNetGrep: fast network schema searches in interactomes.
Publication TypeJournal Article
Year of Publication2008
AuthorsBanks, E, Nabieva, E, Peterson, R, Singh, M
JournalGenome Biol
Date Published2008
KeywordsAlgorithms, Animals, Humans, Protein Interaction Mapping

NetGrep (http://genomics.princeton.edu/singhlab/netgrep/) is a system for searching protein interaction networks for matches to user-supplied 'network schemas'. Each schema consists of descriptions of proteins (for example, their molecular functions or putative domains) along with the desired topology and types of interactions among them. Schemas can thus describe domain-domain interactions, signaling and regulatory pathways, or more complex network patterns. NetGrep provides an advanced graphical interface for specifying schemas and fast algorithms for extracting their matches.

Alternate JournalGenome Biol.