TitleEigen-R2 for dissecting variation in high-dimensional studies.
Publication TypeJournal Article
Year of Publication2008
AuthorsChen, LS, Storey, JD
JournalBioinformatics
Volume24
Issue19
Pagination2260-2
Date Published2008 Oct 1
KeywordsAlgorithms, Gene Expression Profiling, Genetic Variation, Models, Statistical, Software
Abstract

UNLABELLED: We provide a new statistical algorithm and software package called 'eigen-R(2)' for dissecting the variation of a high-dimensional biological dataset with respect to other measured variables of interest. We apply eigen-R(2) to two real-life examples and compare it with simply averaging R(2) over many features.

AVAILABILITY: An R-package eigenR2 is available at http://www.genomine.org/eigenr2/ and will be made publicly available via Bioconductor.
Alternate JournalBioinformatics