TitleChallenges in developing a molecular characterization of cancer.
Publication TypeJournal Article
Year of Publication2002
AuthorsPollack, JR, van de Rijn, M, Botstein, D
JournalSemin Oncol
Date Published2002 Jun
KeywordsGene Expression Profiling, Humans, Neoplasms, Oligonucleotide Array Sequence Analysis

DNA microarrays are widely used to measure gene expression across thousands of genes in parallel. Recently, considerable efforts have been made to utilize this technology to improve our understanding of cancer and to identify novel diagnostic markers and therapeutic targets. Here, we detail some of the challenges in developing a molecular characterization of cancer and in translating these new discoveries towards clinical utility.

Alternate JournalSemin. Oncol.