|Title||Challenges in developing a molecular characterization of cancer.|
|Publication Type||Journal Article|
|Year of Publication||2002|
|Authors||Pollack, JR, van de Rijn, M, Botstein, D|
|Date Published||2002 Jun|
|Keywords||Gene Expression Profiling, Humans, Neoplasms, Oligonucleotide Array Sequence Analysis|
DNA microarrays are widely used to measure gene expression across thousands of genes in parallel. Recently, considerable efforts have been made to utilize this technology to improve our understanding of cancer and to identify novel diagnostic markers and therapeutic targets. Here, we detail some of the challenges in developing a molecular characterization of cancer and in translating these new discoveries towards clinical utility.
|Alternate Journal||Semin. Oncol.|