@article{2543,
  keywords = {Mutation, Gene Expression Regulation, Fungal, Saccharomyces cerevisiae, Culture Media, Genes, Fungal, Genes, Suppressor, Fructosephosphates, Galactosephosphates},
  author = {Patrick Gibney and Ariel Schieler and Jonathan Chen and Jessie Bacha-Hummel and Maxim Botstein and Matthew Volpe and Sanford Silverman and Yifan Xu and Bryson Bennett and Joshua Rabinowitz and David Botstein},
  title = {Common and divergent features of galactose-1-phosphate and fructose-1-phosphate toxicity in yeast.},
  abstract = {<p>Metabolic dysregulation leading to sugar-phosphate accumulation is toxic in organisms ranging from bacteria to humans. By comparing two models of sugar-phosphate toxicity in Saccharomyces cerevisiae, we demonstrate that toxicity occurs, at least in part, through multiple, isomer-specific mechanisms, rather than a single general mechanism.</p>
},
  year = {2018},
  journal = {Mol Biol Cell},
  volume = {29},
  pages = {897-910},
  month = {04/2018},
  issn = {1939-4586},
  doi = {10.1091/mbc.E17-11-0666},
  language = {eng},
}