@article{1759,
  keywords = {Humans, Transcription Factors, Computational Biology, Fungal Proteins, DNA-Binding Proteins, Protein Binding, Models, Molecular, Reproducibility of Results, Basic-Leucine Zipper Transcription Factors, Protein Structure, Secondary, Amino Acid Motifs, G-Box Binding Factors, Static Electricity},
  author = {Jessica Fong and Amy Keating and Mona Singh},
  title = {Predicting specificity in bZIP coiled-coil protein interactions.},
  abstract = {<p>We present a method for predicting protein-protein interactions mediated by the coiled-coil motif. When tested on interactions between nearly all human and yeast bZIP proteins, our method identifies 70\% of strong interactions while maintaining that 92\% of predictions are correct. Furthermore, cross-validation testing shows that including the bZIP experimental data significantly improves performance. Our method can be used to predict bZIP interactions in other genomes and is a promising approach for predicting coiled-coil interactions more generally.</p>},
  year = {2004},
  journal = {Genome Biol},
  volume = {5},
  pages = {R11},
  language = {eng},
}