@article{1578, author = {Qian Zhu and Aaron Wong and Arjun Krishnan and Miriam Aure and Alicja Tadych and Ran Zhang and David Corney and Casey Greene and Lars Bongo and Vessela Kristensen and Moses Charikar and Kai Li and Olga Troyanskaya}, title = {Targeted exploration and analysis of large cross-platform human transcriptomic compendia.}, abstract = {

We present SEEK (search-based exploration of expression compendia; http://seek.princeton.edu/), a query-based search engine for very large transcriptomic data collections, including thousands of human data sets from many different microarray and high-throughput sequencing platforms. SEEK uses a query-level cross-validation-based algorithm to automatically prioritize data sets relevant to the query and a robust search approach to identify genes, pathways and processes co-regulated with the query. SEEK provides multigene query searching with iterative metadata-based search refinement and extensive visualization-based analysis options.

}, year = {2015}, journal = {Nat Methods}, volume = {12}, pages = {211-4, 3 p following 214}, month = {03/2015}, language = {eng}, }