LSI Fellows Program

The Lewis-Sigler Institute seeks applicants for its LSI Fellows Program, which provides independent research and teaching opportunities to exceptional individuals who are expecting or have recently obtained a Ph.D.

Princeton Profiles: Coleen Murphy, researcher and role model

Professor Coleen Murphy has been profiled in a new video available in the Princeton Profiles archive. Click here to watch her interview.

 

In Professor Coleen Murphy's lab, about 20 projects are under way. The professor of molecular biology and the Lewis-Sigler Institute for Integrative Genomics says that juggling multiple projects may be a challenge, but it keeps things exciting.

Shirley Tilghman appointed to The Commission on the Future of Undergraduate Education

Shirley M. Tilghman, president of Princeton University, emeritus, and professor of molecular biology and public affairs, has been named to a national commission under the American Academy of Arts and Sciences entitled The Commission on the Future of Undergraduate Education that will examine how to better the delivery of higher education in the future. Full story.  

John Storey receives the 2015 COPSS Presidents' Award

John Storey, Princeton University's William R. Harman '63 and Mary-Love Harman Professor in Genomics and professor in the Lewis-Sigler Institute for Integrative Genomics, has received the 2015 COPSS Presidents' Award, which recognizes outstanding contributions to statistics by a researcher aged 40 or younger. Presented by the Committee of Presidents of Statistical Societies (COPSS), the award is one of the most prestigious in the field.

David Botstein and Shirley Tilghman named honorees of the Scientific American Worldview 100

Scientific American Worldview names the top 100 contributors of the biotechnology industry, including David Botstein, Anthony B. Evnin ’62 Professor of Genomics, Emeritus, and Shirley Tilghman, President of the University, Emeritus, and Professor of Molecular Biology, the Lewis-Sigler Institute, and Public Affairs.  The list includes researchers, business experts, and administrators who “continue to reshape biotechnology – and the world.”

Full Story.

David Botstein: 2015 Double Helix Medal Honoree

David Botstein, the Anthony B. Evnin '62 Professor of Genomics, Emeritus, will be the recipient of the Cold Spring Harbor Laboratory's Double Helix Medal in November 2015.  The medal "recognizes exceptional individuals who have dedicated their lives to raising awareness of the importance of genetics research for improving the health of people everywhere." 

FACULTY AWARD: Storey receives Mortimer Spiegelman Award for health statisticians under 40

John Storey, the William R. Harman '63 and Mary-Love Harman Professor in Genomics and professor of Molecular Biology and the Lewis-Sigler Institute for Integrative Genomics, has been awarded the 2015 Mortimer Spiegelman Award by the American Public Health Association (APHA). The award was created in 1970 to honor a statistician 40 years or younger who has made outstanding contributions to health statistics, especially public health statistics. The award's intent is to encourage talented young statisticians to become involved in public health. Storey, who also is director of Princeton's Center for Statistics and Machine Learning, will receive the award at the 2015 APHA annual meeting in November.

Ariana Strandburg-Peshkin awarded Procter Fellowship

Ariana Strandburg-Peshkin, QCB graduate student, has been awarded a Charlotte Elizabeth Procter Fellowship for the 2015-16 academic year. Established in 1912 in memory of Charlotte Elizabeth Procter by her son, this fellowship acknowledges her distinguished work in the Department of Quantitative and Computational Biology.

Digging for Meaning in the Big Data of Human Biology

A multi-year effort by researchers from Princeton and other universities and medical schools has taken a big step toward extracting knowledge from these big data collections and opening the door to new understanding of human illnesses. Led by Olga Troyanskaya in the Lewis-Sigler Institute of Integrative Genomics, the team used integrative computational analysis to identify how genetic circuits function and change in different tissues relevant to disease. Published in Nature Genetics.

New approach for performing Genome-wide association studies

A  study published in Nature Genetics by Minsun Song, Wei Hao and John Storey reports a powerful new approach for performing Genome-wide association studies (GWAS) while automatically accounting for hidden population structure.

Benjamin Machta, a Lewis-Sigler Theory Fellow, proposes theoretical model

Mechanics Matter: The action potential is associated with action waves. Benjamin Machta a Theory Fellow from the Lewis-Sigler Institute and Ahmed El Hady from the Princeton Neuroscience Institute have proposed a theoretical model to understand the physical origins of mechanical displacements associated with action potential propagation.

Michael Levine named next Director of the Lewis-Sigler Institute for Integrative Genomics

Michael Levine will become the next Director of the Lewis-Sigler Institute for Integrative Genomics in July, 2015.  Levine, who will also have an appointment in the Molecular Biology Department, will join Princeton from the University of California at Berkeley, where he has been a professor since 1996.  The Levine Lab studies the mechanisms of gene expression during embryonic development.  Levine has made seminal contributions toward the understanding of gene expression and gene regulatory networks in the fruit fly Drosophila melanogaster and the sea s

Shirley Tilghman named Science Careers’ Person of the Year

Science Careers has named Shirley Tilghman, President Emerita and Professor of Molecular Biology and Public Affairs, as their Person of the Year. This annual award is to “honor an individual who has made an especially significant and sustained contribution to the welfare of early-career scientists.”

Caught in the act: Video system for mapping behaviors (Royal Society: Interface)

A new computer-based technology for recording and evaluating animal movements could help researchers conduct studies of the genes and neural circuits that drive behaviors. (Research from Joshua Shaevitz and colleagues in the Lewis-Sigler Institute for Integrative Genomics.)

Studies of animal behavior have come a long way from the days when scientists followed their subjects around with pen and notepad. But although cameras have replaced clipboards, evaluating the resulting videos is still a cumbersome process.

William Bialek Awarded Early Concept Grant For Brain Research

Princeton faculty members William Bialek and Mala Murthy have been awarded Early Concept Grants for Exploratory Research (EAGER) by the National Science Foundation (NSF) to enable new technologies to better understand how complex behaviors emerge from the activity of brain circuits.

Institute of Electrical and Electronics Engineers (IEEE) to award honorary membership to Dr. Shirley Tilghman

Shirley M. Tilghman, president emerita of Princeton University and a professor of genomics and molecular biology, has been elected an honorary member of IEEE for her "leadership in bridging quantitative biology and engineering and for advancing higher education." Tilghman will be recognized at the 2014 IEEE Honors Ceremony in Amsterdam on Aug. 23.

Dr. Tilghman's leadership led to the founding of the Lewis-Sigler Institute for Integrative Genomics.

Joshua Rabinowitz receives Agilent Thought Leader Award

Joshua Rabinowitz, M.D, Ph.D., professor at Princeton University's Department of Chemistry and the Lewis-Sigler Institute for Integrative Genomics, has received an Agilent Thought Leader Award from Agilent Technologies Inc. to support his work on quantitative analysis of cellular metabolism.

Institute of Electrical and Electronics Engineers (IEEE) to award honorary membership to Dr. Shirley Tilghman

Shirley M. Tilghman, president emerita of Princeton University and a professor of genomics and molecular biology, has been elected an honorary member of IEEE for her "leadership in bridging quantitative biology and engineering and for advancing higher education." Tilghman will be recognized at the 2014 IEEE Honors Ceremony in Amsterdam on Aug. 23.

Dr. Tilghman's leadership led to the founding of the Lewis-Sigler Institute for Integrative Genomics.

Krysta Dummit and Daniel Mossing named Goldwater Scholars

Two Integrated Science Princeton students have been awarded Goldwater Scholarships, the premier award for outstanding undergraduates interested in careers in mathematics, the natural sciences and engineering. The 2013-14 winners are juniors Krysta Dummit, a chemistry major,

Shaevitz and Leifer awarded Innovation Fund from Dean for Research

Joshua Shaevitz  and Andrew Leifer  have been awarded an Innovation Fund for New Ideas in the Natural Sciences from the Dean for Research. They will develop an optical system that will be able to simultaneously manipulate and monitor the activity of all neurons in the brain of a freely moving nematode worm with cellular resolution.

Mating is the kiss of death for female worms

Princeton University researchers, led by Coleen Murphy, Associate Professor of Molecular Biology and the Lewis-Sigler Institute for Integrative Genomics, found that male sperm and seminal fluid trigger pathways that cause females to dehydrate, prematurely age, and die.

The presence of male sperm and seminal fluid causes female worms to shrivel and die after giving birth, Princeton University researchers reported in the journal Science. The demise of the female appears to benefit the male worm by removing her from the mating pool for other males.

Princeton Graduate Students Create New Facebook App

The What Would I Say? app was created by Princeton graduate students Harvey Cheng (EE), Ugne Klibaite (QCB), Alex Furge (ORFE), Daniel Jiang (ORFE), Pawel Przytycki (COS), Vicky Yao COS) and Edward Young (PHY) during this year’s HackPrinceton event. The app takes a users’ old Facebook status updates and produces new phrases out of them.

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